Motif ID: Rfx3_Rfx1_Rfx4
Z-value: 2.240



Transcription factors associated with Rfx3_Rfx1_Rfx4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Rfx1 | ENSMUSG00000031706.6 | Rfx1 |
Rfx3 | ENSMUSG00000040929.10 | Rfx3 |
Rfx4 | ENSMUSG00000020037.9 | Rfx4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Rfx4 | mm10_v2_chr10_+_84838143_84838153 | -0.40 | 1.8e-03 | Click! |
Rfx1 | mm10_v2_chr8_+_84066824_84066882 | 0.37 | 4.2e-03 | Click! |
Rfx3 | mm10_v2_chr19_-_28011138_28011181 | -0.06 | 6.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 223 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 37.6 | GO:0016486 | response to dietary excess(GO:0002021) peptide hormone processing(GO:0016486) |
1.0 | 21.9 | GO:0048268 | clathrin coat assembly(GO:0048268) |
1.0 | 19.3 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
4.6 | 18.5 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.7 | 18.4 | GO:0060074 | synapse maturation(GO:0060074) |
0.2 | 17.1 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.5 | 16.0 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
3.2 | 15.8 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
1.1 | 14.7 | GO:0097688 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
0.5 | 13.6 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.6 | 12.9 | GO:0071625 | vocalization behavior(GO:0071625) |
0.3 | 11.9 | GO:0032418 | lysosome localization(GO:0032418) |
1.6 | 11.5 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
2.0 | 9.8 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
2.9 | 8.8 | GO:0010751 | regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) |
0.2 | 8.8 | GO:0045687 | positive regulation of glial cell differentiation(GO:0045687) |
1.4 | 8.5 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
1.9 | 7.7 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
1.3 | 7.5 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
0.7 | 7.5 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 107 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 87.8 | GO:0016021 | integral component of membrane(GO:0016021) |
0.2 | 46.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 26.2 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.7 | 22.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
1.8 | 19.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 19.0 | GO:0005769 | early endosome(GO:0005769) |
0.2 | 16.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.8 | 15.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.1 | 13.7 | GO:0016607 | nuclear speck(GO:0016607) |
0.5 | 13.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 12.6 | GO:0005794 | Golgi apparatus(GO:0005794) |
0.8 | 11.3 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 9.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.3 | 9.2 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.4 | 7.7 | GO:0097228 | sperm principal piece(GO:0097228) |
0.8 | 7.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.5 | 6.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.3 | 6.8 | GO:0031430 | M band(GO:0031430) |
0.0 | 6.1 | GO:0097060 | synaptic membrane(GO:0097060) |
0.1 | 5.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 153 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 38.7 | GO:0008270 | zinc ion binding(GO:0008270) |
0.8 | 38.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 33.3 | GO:0008017 | microtubule binding(GO:0008017) |
3.7 | 22.1 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.8 | 19.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.2 | 15.6 | GO:0030276 | clathrin binding(GO:0030276) |
0.4 | 13.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
1.9 | 11.5 | GO:0015265 | urea channel activity(GO:0015265) |
0.7 | 11.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.7 | 10.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
1.3 | 10.6 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.7 | 10.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.4 | 9.8 | GO:0032183 | SUMO binding(GO:0032183) |
0.1 | 9.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
1.0 | 8.1 | GO:0001618 | virus receptor activity(GO:0001618) |
0.3 | 8.0 | GO:0045296 | cadherin binding(GO:0045296) |
0.9 | 7.6 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.4 | 7.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.1 | 7.0 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
0.2 | 6.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |