Motif ID: Rfx5

Z-value: 0.761


Transcription factors associated with Rfx5:

Gene SymbolEntrez IDGene Name
Rfx5 ENSMUSG00000005774.6 Rfx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx5mm10_v2_chr3_+_94954075_94954226-0.357.1e-03Click!


Activity profile for motif Rfx5.

activity profile for motif Rfx5


Sorted Z-values histogram for motif Rfx5

Sorted Z-values for motif Rfx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_34263209 6.218 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr7_+_46841475 5.292 ENSMUST00000147535.1
Ldha
lactate dehydrogenase A
chr7_-_30664986 5.158 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr17_+_35861318 4.419 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr17_+_35861343 4.058 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr1_-_183147461 3.946 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr2_+_122147680 3.893 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr17_+_37270214 3.866 ENSMUST00000038580.6
H2-M3
histocompatibility 2, M region locus 3
chr17_+_35439155 3.761 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr7_-_105752193 3.697 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr8_+_94214567 3.304 ENSMUST00000079961.6
Nup93
nucleoporin 93
chr11_+_61505138 2.578 ENSMUST00000102657.3
B9d1
B9 protein domain 1
chr17_+_35379608 2.552 ENSMUST00000081435.4
H2-Q4
histocompatibility 2, Q region locus 4
chr7_+_100537192 2.452 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr4_-_35845204 2.365 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr11_+_98682554 2.269 ENSMUST00000017365.8
Psmd3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr7_+_100537052 2.238 ENSMUST00000054310.3
Coa4
cytochrome c oxidase assembly factor 4
chr12_+_108334341 2.072 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr4_-_116627921 2.063 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr17_-_34187219 2.045 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr11_-_3539228 2.040 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
Smtn



smoothelin



chr7_-_45092130 1.993 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr17_-_24886304 1.988 ENSMUST00000044252.5
Nubp2
nucleotide binding protein 2
chr2_-_152398046 1.952 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr17_+_34305883 1.878 ENSMUST00000074557.8
H2-Eb1
histocompatibility 2, class II antigen E beta
chr5_+_139150211 1.827 ENSMUST00000026975.6
Heatr2
HEAT repeat containing 2
chr19_+_37376359 1.674 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr13_+_24831661 1.654 ENSMUST00000038039.2
Tdp2
tyrosyl-DNA phosphodiesterase 2
chr8_-_69996326 1.571 ENSMUST00000177851.1
ENSMUST00000065169.4
Gatad2a

GATA zinc finger domain containing 2A

chr5_-_36830647 1.534 ENSMUST00000031002.3
Man2b2
mannosidase 2, alpha B2
chr7_-_45091713 1.499 ENSMUST00000141576.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr10_-_19011948 1.465 ENSMUST00000105527.1
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr11_+_72441341 1.461 ENSMUST00000045633.5
Mybbp1a
MYB binding protein (P160) 1a
chr18_-_51865881 1.352 ENSMUST00000091905.2
Gm4950
predicted pseudogene 4950
chr3_-_95882031 1.304 ENSMUST00000161994.1
Gm129
predicted gene 129
chr17_+_34398802 1.274 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
BC051142



cDNA sequence BC051142



chr2_-_128687354 1.248 ENSMUST00000110332.1
ENSMUST00000110333.1
ENSMUST00000014499.3
Anapc1


anaphase promoting complex subunit 1


chr10_-_7663245 1.240 ENSMUST00000163085.1
ENSMUST00000159917.1
Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr8_+_84969587 1.196 ENSMUST00000109734.1
ENSMUST00000005292.8
Prdx2

peroxiredoxin 2

chr5_-_125294107 1.112 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr3_-_95882193 1.086 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chrX_-_160138375 0.987 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr6_-_29165003 0.938 ENSMUST00000007993.9
Rbm28
RNA binding motif protein 28
chr1_+_134405984 0.891 ENSMUST00000173908.1
Cyb5r1
cytochrome b5 reductase 1
chr9_+_44773191 0.788 ENSMUST00000147559.1
Ift46
intraflagellar transport 46
chr17_+_34187789 0.753 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr18_+_60803838 0.683 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
Cd74


CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)


chr17_+_34187545 0.647 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_-_7663569 0.636 ENSMUST00000162606.1
Pcmt1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr10_-_123196916 0.613 ENSMUST00000020334.7
Usp15
ubiquitin specific peptidase 15
chr7_-_101921186 0.577 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
Lrrc51


leucine rich repeat containing 51


chr11_+_117523526 0.575 ENSMUST00000132261.1
Gm11734
predicted gene 11734
chr7_-_101921175 0.555 ENSMUST00000098236.2
Lrrc51
leucine rich repeat containing 51
chr19_-_10482874 0.545 ENSMUST00000038842.3
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr19_-_4615647 0.536 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_136676413 0.524 ENSMUST00000181491.1
Gm19705
predicted gene, 19705
chr14_+_111675113 0.311 ENSMUST00000042767.7
Slitrk5
SLIT and NTRK-like family, member 5
chr8_+_27042555 0.249 ENSMUST00000033875.8
ENSMUST00000098851.4
Prosc

proline synthetase co-transcribed

chr8_-_89187560 0.240 ENSMUST00000093326.2
Gm5356
predicted pseudogene 5356
chr3_-_95882232 0.205 ENSMUST00000161866.1
Gm129
predicted gene 129
chr19_+_32757497 0.202 ENSMUST00000013807.7
Pten
phosphatase and tensin homolog
chr17_+_24886643 0.158 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr6_-_8259098 0.125 ENSMUST00000012627.4
Rpa3
replication protein A3
chr19_-_8819314 0.057 ENSMUST00000096751.4
Ttc9c
tetratricopeptide repeat domain 9C
chr9_-_51102062 0.043 ENSMUST00000170947.1
4833427G06Rik
RIKEN cDNA 4833427G06 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0002339 B cell selection(GO:0002339)
1.3 3.9 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
1.1 5.3 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.8 3.9 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.5 1.5 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.4 4.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.4 1.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.4 1.1 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.4 3.9 GO:0060539 diaphragm development(GO:0060539)
0.3 1.4 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 1.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 2.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 3.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 0.2 GO:1901630 negative regulation of presynaptic membrane organization(GO:1901630)
0.2 1.5 GO:0006013 mannose metabolic process(GO:0006013)
0.2 0.7 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.2 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.2 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 1.0 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 3.7 GO:0043171 peptide catabolic process(GO:0043171)
0.1 3.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 2.1 GO:0043486 histone exchange(GO:0043486)
0.1 2.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.9 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.1 5.2 GO:0051225 spindle assembly(GO:0051225)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 2.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.9 GO:0034341 response to interferon-gamma(GO:0034341)
0.0 2.0 GO:0021510 spinal cord development(GO:0021510)
0.0 0.9 GO:0016126 sterol biosynthetic process(GO:0016126)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.8 11.4 GO:0042611 MHC protein complex(GO:0042611)
0.6 5.2 GO:0070652 HAUS complex(GO:0070652)
0.5 8.5 GO:0005652 nuclear lamina(GO:0005652)
0.5 1.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.4 5.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 1.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 2.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 1.4 GO:0042825 TAP complex(GO:0042825)
0.2 2.6 GO:0036038 MKS complex(GO:0036038)
0.1 1.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 2.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 4.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.3 GO:0005643 nuclear pore(GO:0005643)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 6.7 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.1 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.9 3.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.9 2.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.7 6.2 GO:0015643 toxic substance binding(GO:0015643)
0.5 7.7 GO:0046977 TAP binding(GO:0046977)
0.4 3.9 GO:0015197 peptide transporter activity(GO:0015197)
0.4 1.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 1.0 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 3.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.0 GO:0070628 proteasome binding(GO:0070628)
0.1 1.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.5 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 2.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 3.9 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.6 GO:0030674 protein binding, bridging(GO:0030674)