Motif ID: Rhox11

Z-value: 0.419


Transcription factors associated with Rhox11:

Gene SymbolEntrez IDGene Name
Rhox11 ENSMUSG00000051038.9 Rhox11



Activity profile for motif Rhox11.

activity profile for motif Rhox11


Sorted Z-values histogram for motif Rhox11

Sorted Z-values for motif Rhox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_17574268 4.073 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 2.631 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_-_139130159 2.328 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr11_+_29373618 2.309 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr5_+_21186267 1.944 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr3_+_156561792 1.730 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr12_+_74288735 1.684 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr3_-_121171678 1.464 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
 Rwdd3




RWD domain containing 3




chr1_-_162866502 1.456 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr15_+_8169067 1.394 ENSMUST00000110617.1
 2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr10_+_58394361 1.261 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chr13_+_49653297 1.260 ENSMUST00000021824.7
 Nol8
nucleolar protein 8
chr5_+_111733924 1.258 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr8_+_104831572 1.214 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chr10_+_58394381 1.160 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr13_-_3611064 1.085 ENSMUST00000096069.3
 BC016423
cDNA sequence BC016423
chr16_+_29579331 1.076 ENSMUST00000160597.1
 Opa1
optic atrophy 1
chr10_-_59951753 0.988 ENSMUST00000020308.3
 Ddit4
DNA-damage-inducible transcript 4
chr2_-_150362708 0.910 ENSMUST00000051153.5
 3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr7_-_28008416 0.879 ENSMUST00000180024.1
 Zfp850
zinc finger protein 850
chr9_-_20521375 0.830 ENSMUST00000068296.7
ENSMUST00000174462.1
 Zfp266

zinc finger protein 266

chr16_+_29579347 0.793 ENSMUST00000038867.6
ENSMUST00000161186.1
 Opa1

optic atrophy 1

chr2_+_178118975 0.778 ENSMUST00000108917.1
 Phactr3
phosphatase and actin regulator 3
chr15_+_36179299 0.774 ENSMUST00000047348.3
 Spag1
sperm associated antigen 1
chr3_+_127791374 0.722 ENSMUST00000171621.1
 Tifa
TRAF-interacting protein with forkhead-associated domain
chr16_+_23107413 0.691 ENSMUST00000023599.6
ENSMUST00000168891.1
 Eif4a2

eukaryotic translation initiation factor 4A2

chr6_-_34977999 0.677 ENSMUST00000044387.7
 2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr7_+_5051515 0.667 ENSMUST00000069324.5
 Zfp580
zinc finger protein 580
chr8_+_3353415 0.593 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chr11_+_98741805 0.574 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr8_+_72492915 0.562 ENSMUST00000181452.1
 Gm17435
predicted gene, 17435
chr16_+_23107754 0.561 ENSMUST00000077605.5
ENSMUST00000115341.3
 Eif4a2

eukaryotic translation initiation factor 4A2

chr1_+_99772765 0.538 ENSMUST00000086738.3
 Cntnap5b
contactin associated protein-like 5B
chr7_-_46795881 0.535 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr5_+_121220191 0.527 ENSMUST00000119892.2
ENSMUST00000042614.6
 Gm15800

predicted gene 15800

chr18_+_6765171 0.489 ENSMUST00000097680.5
 Rab18
RAB18, member RAS oncogene family
chr1_-_175688353 0.487 ENSMUST00000104984.1
 Chml
choroideremia-like
chr3_+_68468162 0.462 ENSMUST00000182532.1
 Schip1
schwannomin interacting protein 1
chr17_+_79614900 0.461 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr18_-_24709348 0.455 ENSMUST00000067987.1
 Gm9955
predicted gene 9955
chr9_-_16378231 0.450 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chrX_-_111536325 0.449 ENSMUST00000156639.1
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr18_+_62977854 0.439 ENSMUST00000150267.1
 Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr5_+_143933059 0.436 ENSMUST00000166847.1
 Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr7_-_46795661 0.421 ENSMUST00000123725.1
 Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr13_+_47043499 0.388 ENSMUST00000037025.8
ENSMUST00000143868.1
 Kdm1b

lysine (K)-specific demethylase 1B

chr14_-_20496780 0.377 ENSMUST00000022353.3
 Mss51
MSS51 mitochondrial translational activator
chr9_-_8134294 0.361 ENSMUST00000037397.6
 AK129341
cDNA sequence AK129341
chr2_-_131352857 0.358 ENSMUST00000059372.4
 Rnf24
ring finger protein 24
chr4_+_126556935 0.357 ENSMUST00000048391.8
 Clspn
claspin
chr15_+_25742314 0.356 ENSMUST00000135981.1
 Myo10
myosin X
chr4_+_126556994 0.355 ENSMUST00000147675.1
 Clspn
claspin
chr14_-_46822232 0.352 ENSMUST00000111817.1
ENSMUST00000079314.5
 Gmfb

glia maturation factor, beta

chr7_+_46796088 0.347 ENSMUST00000006774.4
ENSMUST00000165031.1
 Gtf2h1

general transcription factor II H, polypeptide 1

chr6_-_106800051 0.328 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
 Crbn


cereblon


chr2_-_5862923 0.324 ENSMUST00000071016.2
 Gm13199
predicted gene 13199
chr5_+_93093428 0.290 ENSMUST00000074733.7
 Sept11
septin 11
chr9_-_20644726 0.284 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
 Fbxl12




F-box and leucine-rich repeat protein 12




chr19_-_8818924 0.274 ENSMUST00000153281.1
 Ttc9c
tetratricopeptide repeat domain 9C
chr11_-_30198232 0.264 ENSMUST00000102838.3
 Sptbn1
spectrin beta, non-erythrocytic 1
chr8_+_94386438 0.259 ENSMUST00000161576.1
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_+_54264839 0.258 ENSMUST00000146114.1
 Chn2
chimerin (chimaerin) 2
chr8_-_105827190 0.241 ENSMUST00000041400.5
 Ranbp10
RAN binding protein 10
chr15_+_41789495 0.204 ENSMUST00000090095.5
ENSMUST00000022918.7
 Oxr1

oxidation resistance 1

chr11_-_5381734 0.198 ENSMUST00000172492.1
 Znrf3
zinc and ring finger 3
chr6_+_128662379 0.196 ENSMUST00000032518.4
 Clec2h
C-type lectin domain family 2, member h
chr9_-_60838200 0.168 ENSMUST00000063858.7
 Gm9869
predicted gene 9869
chr13_+_95325195 0.119 ENSMUST00000045909.7
 Zbed3
zinc finger, BED domain containing 3
chr1_+_87853264 0.100 ENSMUST00000027517.7
 Dgkd
diacylglycerol kinase, delta
chr15_+_7129557 0.093 ENSMUST00000067190.5
ENSMUST00000164529.1
 Lifr

leukemia inhibitory factor receptor

chr11_-_97700327 0.066 ENSMUST00000018681.7
 Pcgf2
polycomb group ring finger 2
chr5_-_114858682 0.058 ENSMUST00000066959.4
 Gm9936
predicted gene 9936
chr9_+_50768228 0.046 ENSMUST00000042391.6
 Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr2_-_57113053 0.040 ENSMUST00000112627.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr9_-_44713196 0.030 ENSMUST00000144251.1
ENSMUST00000156918.1
 Phldb1

pleckstrin homology-like domain, family B, member 1

chr4_-_108848619 0.015 ENSMUST00000164855.1
 A730015C16Rik
RIKEN cDNA A730015C16 gene
chr8_+_94386486 0.015 ENSMUST00000034220.7
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.6 1.9 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.6 2.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 1.5 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2 1.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 2.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.6 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 1.5 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.9 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.9 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 1.0 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.7 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 1.7 GO:0007631 feeding behavior(GO:0007631)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 1.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.7 GO:0038191 neuropilin binding(GO:0038191)
0.3 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.6 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 2.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.2 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 1.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)