Motif ID: Runx3

Z-value: 0.605


Transcription factors associated with Runx3:

Gene SymbolEntrez IDGene Name
Runx3 ENSMUSG00000070691.4 Runx3



Activity profile for motif Runx3.

activity profile for motif Runx3


Sorted Z-values histogram for motif Runx3

Sorted Z-values for motif Runx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Runx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 78 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_20181773 5.239 ENSMUST00000024011.8
 Kcnk5
potassium channel, subfamily K, member 5
chr3_-_154330543 3.209 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr13_-_22041352 3.121 ENSMUST00000102977.2
 Hist1h4i
histone cluster 1, H4i
chr13_-_23551648 2.149 ENSMUST00000102971.1
 Hist1h4f
histone cluster 1, H4f
chr7_+_141216626 1.895 ENSMUST00000141804.1
ENSMUST00000148975.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr13_-_23698454 1.730 ENSMUST00000102967.1
 Hist1h4c
histone cluster 1, H4c
chr17_+_27556668 1.709 ENSMUST00000117254.1
ENSMUST00000118570.1
 Hmga1

high mobility group AT-hook 1

chr17_+_27556641 1.697 ENSMUST00000119486.1
ENSMUST00000118599.1
 Hmga1

high mobility group AT-hook 1

chr17_+_27556613 1.697 ENSMUST00000117600.1
ENSMUST00000114888.3
 Hmga1

high mobility group AT-hook 1

chr15_+_40655020 1.660 ENSMUST00000053467.4
 Zfpm2
zinc finger protein, multitype 2
chr11_-_89302545 1.602 ENSMUST00000061728.3
 Nog
noggin
chr13_-_21832194 1.600 ENSMUST00000102979.1
 Hist1h4n
histone cluster 1, H4n
chrX_+_99136119 1.548 ENSMUST00000052839.6
 Efnb1
ephrin B1
chr18_-_47368446 1.521 ENSMUST00000076043.6
ENSMUST00000135790.1
 Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr7_-_78783026 1.467 ENSMUST00000032841.5
 Mrpl46
mitochondrial ribosomal protein L46
chr18_-_77713978 1.402 ENSMUST00000074653.4
 8030462N17Rik
RIKEN cDNA 8030462N17 gene
chr13_+_21735055 1.340 ENSMUST00000087714.4
 Hist1h4j
histone cluster 1, H4j
chr13_+_51645232 1.250 ENSMUST00000075853.5
 Cks2
CDC28 protein kinase regulatory subunit 2
chr11_-_5878207 1.211 ENSMUST00000102922.3
 Pold2
polymerase (DNA directed), delta 2, regulatory subunit
chr6_-_100671126 1.180 ENSMUST00000089245.6
ENSMUST00000113312.2
ENSMUST00000170667.1
 Shq1


SHQ1 homolog (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 9.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 5.1 GO:0006284 base-excision repair(GO:0006284)
0.5 4.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 3.2 GO:0021884 forebrain neuron development(GO:0021884)
0.1 2.0 GO:0060009 Sertoli cell development(GO:0060009)
0.6 1.7 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.4 1.6 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.3 GO:0007127 meiosis I(GO:0007127)
0.4 1.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.2 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.4 1.1 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.2 0.9 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.9 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.9 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.9 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 0.8 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.2 GO:0000786 nucleosome(GO:0000786)
0.7 5.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.5 3.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 2.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 1.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.2 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.9 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.9 GO:0045120 pronucleus(GO:0045120)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.8 GO:0042393 histone binding(GO:0042393)
0.6 5.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 4.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0019955 cytokine binding(GO:0019955)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.9 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.8 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)