Motif ID: Rxrb

Z-value: 0.786


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34031787_34031821-0.621.4e-07Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Showing 1 to 20 of 129 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_136143497 6.727 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr5_-_116422858 6.169 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr6_-_23248264 5.501 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr4_-_117178726 4.686 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr18_+_57142782 4.219 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr10_+_93641041 3.998 ENSMUST00000020204.4
 Ntn4
netrin 4
chr10_-_88146867 3.845 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein



chr14_-_118052235 3.725 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr4_+_44300876 3.650 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr5_+_110839973 3.602 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr1_+_146420434 3.518 ENSMUST00000163646.1
 Gm5263
predicted gene 5263
chr18_-_80713062 3.416 ENSMUST00000170905.1
ENSMUST00000078049.4
 Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr1_+_84839833 3.308 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr11_+_40733936 3.262 ENSMUST00000127382.1
 Nudcd2
NudC domain containing 2
chr11_-_40733373 3.141 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr15_-_78529617 3.019 ENSMUST00000023075.8
 C1qtnf6
C1q and tumor necrosis factor related protein 6
chr6_+_113531675 3.015 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr12_+_119945957 2.989 ENSMUST00000058644.8
 Tmem196
transmembrane protein 196
chr11_+_40733639 2.875 ENSMUST00000020578.4
 Nudcd2
NudC domain containing 2
chr8_+_72135247 2.864 ENSMUST00000003575.9
 Tpm4
tropomyosin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.7 GO:0071398 cellular response to fatty acid(GO:0071398)
0.9 5.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 4.9 GO:0010388 cullin deneddylation(GO:0010388)
0.9 4.7 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 4.2 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.8 4.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 3.9 GO:0051028 mRNA transport(GO:0051028)
0.5 3.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.9 3.7 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 3.7 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.9 3.6 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
1.1 3.4 GO:0060854 patterning of lymph vessels(GO:0060854)
0.6 3.4 GO:1903753 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) hard palate development(GO:0060022) negative regulation of p38MAPK cascade(GO:1903753)
0.1 3.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.4 3.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 3.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 3.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.3 2.5 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.3 2.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.8 2.4 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.1 GO:0000776 kinetochore(GO:0000776)
0.0 5.6 GO:0000785 chromatin(GO:0000785)
0.1 5.1 GO:0005581 collagen trimer(GO:0005581)
0.2 4.4 GO:0035371 microtubule plus-end(GO:0035371)
0.2 4.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 4.0 GO:0005938 cell cortex(GO:0005938)
0.4 3.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 3.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 3.5 GO:0005604 basement membrane(GO:0005604)
0.7 3.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 3.1 GO:0031011 Ino80 complex(GO:0031011)
0.0 3.0 GO:0000793 condensed chromosome(GO:0000793)
0.2 2.9 GO:0002102 podosome(GO:0002102)
0.0 2.6 GO:0043235 receptor complex(GO:0043235)
0.8 2.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 2.5 GO:0016234 inclusion body(GO:0016234)
0.1 2.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 6.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.8 5.9 GO:0043237 laminin-1 binding(GO:0043237)
0.0 4.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.5 4.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.3 4.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 3.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 3.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 3.4 GO:0097016 L27 domain binding(GO:0097016)
0.4 3.4 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.2 3.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.0 2.6 GO:0051087 chaperone binding(GO:0051087)
0.1 2.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 2.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.5 2.0 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.0 GO:0043014 alpha-tubulin binding(GO:0043014)