Motif ID: Scrt1

Z-value: 1.997


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.834.4e-16Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144939823 25.741 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr10_+_56377300 20.823 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr7_-_30973367 20.725 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr16_+_16213318 18.390 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr13_+_99100698 16.968 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr7_-_30973399 15.742 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr4_-_134012381 15.396 ENSMUST00000176113.1
 Lin28a
lin-28 homolog A (C. elegans)
chr7_-_30973464 14.611 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr15_-_101054399 13.738 ENSMUST00000178140.1
 Fignl2
fidgetin-like 2
chr2_+_131234043 13.111 ENSMUST00000041362.5
ENSMUST00000110199.2
 Mavs

mitochondrial antiviral signaling protein

chr7_+_110221697 12.854 ENSMUST00000033325.7
 Swap70
SWA-70 protein
chr11_-_55419898 12.736 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr18_+_56432116 12.520 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr15_-_98004634 12.440 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr3_+_34649987 12.415 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr8_+_31187317 12.181 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
 Fut10



fucosyltransferase 10



chr9_-_27155418 11.882 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr12_-_40038025 11.765 ENSMUST00000101472.3
 Arl4a
ADP-ribosylation factor-like 4A
chr9_+_91368811 11.730 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr6_+_128375456 11.668 ENSMUST00000100926.2
 4933413G19Rik
RIKEN cDNA 4933413G19 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
17.0 51.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.9 31.0 GO:0030953 astral microtubule organization(GO:0030953)
3.7 25.7 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.6 22.4 GO:0050873 brown fat cell differentiation(GO:0050873)
3.2 22.2 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.1 21.6 GO:0008380 RNA splicing(GO:0008380)
6.9 20.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
1.5 19.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
6.1 18.4 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
3.1 18.4 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
1.9 15.4 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.6 13.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
4.4 13.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.5 13.0 GO:0018345 protein palmitoylation(GO:0018345)
0.3 12.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
1.0 12.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.8 12.2 GO:0036065 fucosylation(GO:0036065)
1.5 11.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.0 11.6 GO:0044458 motile cilium assembly(GO:0044458)
0.2 11.4 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.5 51.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 34.6 GO:0005794 Golgi apparatus(GO:0005794)
2.5 30.3 GO:0030057 desmosome(GO:0030057)
0.1 29.6 GO:0005813 centrosome(GO:0005813)
0.6 25.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 24.3 GO:0031012 extracellular matrix(GO:0031012)
0.2 24.0 GO:0031514 motile cilium(GO:0031514)
0.3 22.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
2.1 20.8 GO:0005916 fascia adherens(GO:0005916)
1.3 19.3 GO:0042555 MCM complex(GO:0042555)
0.1 19.3 GO:0005681 spliceosomal complex(GO:0005681)
0.2 18.6 GO:0005604 basement membrane(GO:0005604)
0.1 17.3 GO:0005884 actin filament(GO:0005884)
0.2 16.4 GO:0005814 centriole(GO:0005814)
0.3 15.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 15.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
3.2 12.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.0 12.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 11.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 11.4 GO:0005635 nuclear envelope(GO:0005635)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 56.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 38.5 GO:0003924 GTPase activity(GO:0003924)
0.4 28.5 GO:0005518 collagen binding(GO:0005518)
1.5 27.8 GO:0035198 miRNA binding(GO:0035198)
0.3 26.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
1.1 25.7 GO:0070064 proline-rich region binding(GO:0070064)
4.2 20.8 GO:0071253 connexin binding(GO:0071253)
4.0 19.8 GO:0032027 myosin light chain binding(GO:0032027)
1.5 18.4 GO:0045294 alpha-catenin binding(GO:0045294)
1.1 15.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 14.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 13.7 GO:0005178 integrin binding(GO:0005178)
3.3 13.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 12.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.8 12.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 12.2 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.3 12.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
3.8 11.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.4 11.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
2.1 10.6 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)