Motif ID: Scrt2

Z-value: 1.400


Transcription factors associated with Scrt2:

Gene SymbolEntrez IDGene Name
Scrt2 ENSMUSG00000060257.2 Scrt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt2mm10_v2_chr2_+_152081529_152081624-0.761.8e-12Click!


Activity profile for motif Scrt2.

activity profile for motif Scrt2


Sorted Z-values histogram for motif Scrt2

Sorted Z-values for motif Scrt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt2

PNG image of the network

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Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_56377300 18.011 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr16_+_16213318 13.716 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr3_+_34649987 11.653 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr7_-_30973399 11.292 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr7_-_30973367 10.831 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr10_+_26229707 10.792 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr7_-_30973464 10.704 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr6_-_53820764 10.592 ENSMUST00000127748.2
 Tril
TLR4 interactor with leucine-rich repeats
chr9_+_91368811 10.300 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368970 9.887 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr2_-_164443177 9.596 ENSMUST00000017153.3
 Sdc4
syndecan 4
chr3_+_130180882 9.568 ENSMUST00000106353.1
ENSMUST00000080335.4
 Col25a1

collagen, type XXV, alpha 1

chr11_-_55419898 8.508 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr7_-_25250720 8.495 ENSMUST00000116343.2
ENSMUST00000045847.8
 Erf

Ets2 repressor factor

chr11_-_100355383 8.456 ENSMUST00000146878.2
 Hap1
huntingtin-associated protein 1
chr12_-_40037387 8.041 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr8_+_31187317 8.022 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
 Fut10



fucosyltransferase 10



chr6_-_135168162 7.690 ENSMUST00000045855.7
 Hebp1
heme binding protein 1
chr9_-_27155418 7.651 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr15_-_98004634 7.597 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
10.9 32.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
6.0 18.0 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.5 14.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
4.6 13.7 GO:0086069 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) bundle of His cell to Purkinje myocyte communication(GO:0086069)
1.7 11.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 11.5 GO:0042168 heme metabolic process(GO:0042168)
0.5 10.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.5 10.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.9 9.6 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.6 9.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 9.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
1.3 9.1 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
2.1 8.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.7 8.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 8.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.5 8.0 GO:0036065 fucosylation(GO:0036065)
0.2 8.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.9 7.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.7 7.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 7.1 GO:0008105 asymmetric protein localization(GO:0008105)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.5 32.8 GO:0061689 tricellular tight junction(GO:0061689)
1.8 21.4 GO:0030057 desmosome(GO:0030057)
1.8 18.0 GO:0005916 fascia adherens(GO:0005916)
0.0 15.3 GO:0098793 presynapse(GO:0098793)
0.1 15.0 GO:0031012 extracellular matrix(GO:0031012)
0.3 12.1 GO:0043034 costamere(GO:0043034)
0.2 11.9 GO:0030667 secretory granule membrane(GO:0030667)
0.2 11.6 GO:0005581 collagen trimer(GO:0005581)
1.8 10.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 9.4 GO:0005604 basement membrane(GO:0005604)
2.3 9.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 9.0 GO:0005925 focal adhesion(GO:0005925)
0.0 8.8 GO:0005667 transcription factor complex(GO:0005667)
2.1 8.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 8.5 GO:0005776 autophagosome(GO:0005776)
0.6 7.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 7.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 6.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 6.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 5.7 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 32.8 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 22.6 GO:0030276 clathrin binding(GO:0030276)
0.3 20.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 20.5 GO:0005518 collagen binding(GO:0005518)
0.0 19.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
1.0 18.4 GO:0035198 miRNA binding(GO:0035198)
3.6 18.0 GO:0071253 connexin binding(GO:0071253)
0.1 15.8 GO:0003924 GTPase activity(GO:0003924)
1.1 13.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 11.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.8 10.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.7 10.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.9 9.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 9.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 9.6 GO:0051015 actin filament binding(GO:0051015)
1.8 9.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.1 8.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 8.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 7.8 GO:0005516 calmodulin binding(GO:0005516)
0.1 7.7 GO:0020037 heme binding(GO:0020037)