Motif ID: Sin3a

Z-value: 1.350


Transcription factors associated with Sin3a:

Gene SymbolEntrez IDGene Name
Sin3a ENSMUSG00000042557.8 Sin3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sin3amm10_v2_chr9_+_57072024_570720480.364.9e-03Click!


Activity profile for motif Sin3a.

activity profile for motif Sin3a


Sorted Z-values histogram for motif Sin3a

Sorted Z-values for motif Sin3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Sin3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_69360294 10.848 ENSMUST00000033532.6
Aff2
AF4/FMR2 family, member 2
chr10_-_120476469 10.647 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2

high mobility group AT-hook 2

chr3_-_66981279 8.326 ENSMUST00000162098.2
Shox2
short stature homeobox 2
chr5_-_106458440 6.266 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr18_-_72351009 5.420 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr6_-_39206782 5.406 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr18_-_72351029 5.254 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chr15_-_78120011 4.989 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr5_+_117413977 4.866 ENSMUST00000180430.1
Ksr2
kinase suppressor of ras 2
chrX_-_104201126 4.698 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chrX_-_104201099 4.604 ENSMUST00000087879.4
C77370
expressed sequence C77370
chr2_-_36105271 4.507 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr7_+_36698002 4.410 ENSMUST00000021641.6
Tshz3
teashirt zinc finger family member 3
chr18_+_64340225 4.368 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr1_+_167001457 4.163 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr1_-_56971762 3.908 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr9_+_3532295 3.884 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr4_+_54947976 3.791 ENSMUST00000098070.3
Zfp462
zinc finger protein 462
chr13_-_99516537 3.789 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr13_-_107890059 3.603 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 539 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.6 GO:0006397 mRNA processing(GO:0006397)
2.1 10.6 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
1.1 10.0 GO:0060613 fat pad development(GO:0060613)
0.9 9.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 8.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.5 8.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.8 8.3 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.5 8.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 7.5 GO:2001222 regulation of neuron migration(GO:2001222)
2.0 6.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.7 5.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 5.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
1.8 5.3 GO:0050975 sensory perception of touch(GO:0050975)
0.6 5.3 GO:0061038 uterus morphogenesis(GO:0061038)
1.0 5.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.2 4.9 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 4.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.4 4.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 4.7 GO:0086011 membrane repolarization during action potential(GO:0086011)
1.5 4.6 GO:0097402 neuroblast migration(GO:0097402)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 219 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.3 GO:0016607 nuclear speck(GO:0016607)
1.1 11.6 GO:0032584 growth cone membrane(GO:0032584)
0.3 9.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.9 9.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 9.0 GO:0005814 centriole(GO:0005814)
0.3 8.4 GO:0043194 axon initial segment(GO:0043194)
0.0 7.4 GO:0005694 chromosome(GO:0005694)
0.0 6.6 GO:0030426 growth cone(GO:0030426)
0.1 6.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 6.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.3 6.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 5.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
1.1 5.7 GO:0030314 junctional membrane complex(GO:0030314)
0.0 5.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 5.4 GO:0016605 PML body(GO:0016605)
0.0 5.3 GO:0005681 spliceosomal complex(GO:0005681)
0.1 5.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 5.0 GO:0030014 CCR4-NOT complex(GO:0030014)
1.6 4.9 GO:0042642 actomyosin, myosin complex part(GO:0042642)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 310 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.1 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
1.9 11.5 GO:0005042 netrin receptor activity(GO:0005042)
1.4 11.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
1.0 10.9 GO:0003680 AT DNA binding(GO:0003680)
0.5 10.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 9.3 GO:0003682 chromatin binding(GO:0003682)
0.3 8.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.2 8.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 8.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 7.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 7.5 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 7.2 GO:0045182 translation regulator activity(GO:0045182)
0.1 6.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.3 6.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 6.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 6.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.7 6.0 GO:0046790 virion binding(GO:0046790)
0.4 5.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 5.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.6 5.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)