Motif ID: Smad4

Z-value: 0.964


Transcription factors associated with Smad4:

Gene SymbolEntrez IDGene Name
Smad4 ENSMUSG00000024515.7 Smad4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smad4mm10_v2_chr18_-_73703739_737038060.047.5e-01Click!


Activity profile for motif Smad4.

activity profile for motif Smad4


Sorted Z-values histogram for motif Smad4

Sorted Z-values for motif Smad4



Network of associatons between targets according to the STRING database.



First level regulatory network of Smad4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_22042949 6.184 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr10_-_127534540 5.509 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr13_-_21832194 4.493 ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr11_-_95514570 3.934 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr19_+_5740885 3.761 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr13_+_23581563 3.490 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chr7_-_70360593 3.203 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr1_-_16770138 2.829 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr13_-_23551648 2.778 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr4_-_148130678 2.776 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr7_+_24862193 2.562 ENSMUST00000052897.4
ENSMUST00000170837.2
Gm9844
Gm9844
predicted pseudogene 9844
predicted pseudogene 9844
chr13_+_23531044 2.507 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr3_-_96220880 2.273 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr3_+_127633134 2.258 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr13_+_21735055 2.152 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr14_-_25903100 2.067 ENSMUST00000052286.8
Plac9a
placenta specific 9a
chr13_+_22043189 2.032 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr12_+_103314944 1.944 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr11_-_89302545 1.892 ENSMUST00000061728.3
Nog
noggin
chr10_+_80150448 1.890 ENSMUST00000153477.1
Midn
midnolin
chr7_-_27181149 1.888 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr6_+_54040078 1.711 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chr19_+_46328179 1.623 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chrX_+_56779437 1.578 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr18_+_57133065 1.575 ENSMUST00000075770.6
Megf10
multiple EGF-like-domains 10
chr7_+_45216671 1.568 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr8_+_54954728 1.509 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr17_+_75178911 1.507 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr17_+_75178797 1.488 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr15_+_39076885 1.484 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr13_-_23934156 1.482 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr2_+_27079371 1.437 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr4_-_95052170 1.371 ENSMUST00000058555.2
Jun
Jun oncogene
chr14_-_104467984 1.367 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr7_+_45215753 1.340 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr14_-_54577578 1.328 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr2_-_173276144 1.269 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr6_+_54039558 1.201 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr1_+_187997835 1.190 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr14_+_57826210 1.158 ENSMUST00000022538.3
Mrp63
mitochondrial ribosomal protein 63
chr17_-_29888570 1.148 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr1_+_187997821 1.122 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr1_-_173367638 1.102 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr10_-_42583628 1.079 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr10_-_92164666 1.075 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr15_+_81936911 1.062 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr2_-_128967725 1.048 ENSMUST00000099385.2
Gm10762
predicted gene 10762
chr8_-_92356103 1.022 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr6_-_138422898 1.005 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr19_-_40271506 0.985 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr6_+_15720654 0.982 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr10_+_75589363 0.982 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr4_-_117178726 0.973 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr14_+_12189943 0.953 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr4_+_97772734 0.942 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr2_+_152736244 0.932 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr4_+_148130883 0.924 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr5_+_7179299 0.911 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr4_+_127172866 0.895 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr17_-_25081138 0.893 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr18_-_35498856 0.845 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr5_+_30913398 0.835 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr1_+_177445660 0.827 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr15_+_81936753 0.824 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chrX_+_99136119 0.811 ENSMUST00000052839.6
Efnb1
ephrin B1
chr11_-_3931789 0.770 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr11_-_3931960 0.762 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr8_-_109251698 0.756 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr17_-_70851710 0.753 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr8_-_34146974 0.744 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr10_+_91082940 0.743 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chr6_-_72958097 0.733 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr5_-_24601961 0.726 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_+_133011506 0.718 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr19_-_23448322 0.699 ENSMUST00000036069.6
Mamdc2
MAM domain containing 2
chr7_+_4690760 0.694 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr11_-_5261558 0.690 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr7_-_30362772 0.686 ENSMUST00000046351.5
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chr4_+_128688726 0.678 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr16_-_55283237 0.673 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr3_-_116968969 0.660 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr10_+_33905015 0.650 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr6_+_54039935 0.636 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr5_-_137741102 0.634 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr3_+_88607742 0.627 ENSMUST00000175903.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr6_-_83775767 0.621 ENSMUST00000014892.6
Tex261
testis expressed gene 261
chr3_+_96221111 0.620 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chr14_-_57826128 0.609 ENSMUST00000022536.2
Ska3
spindle and kinetochore associated complex subunit 3
chr2_+_32628390 0.599 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr12_+_76404168 0.590 ENSMUST00000080449.5
Hspa2
heat shock protein 2
chr17_+_46646225 0.580 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr11_+_60699718 0.580 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr5_+_19907502 0.553 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_106160101 0.540 ENSMUST00000045923.3
Limd2
LIM domain containing 2
chr14_-_54554359 0.539 ENSMUST00000022784.8
Haus4
HAUS augmin-like complex, subunit 4
chr5_+_111417263 0.521 ENSMUST00000094463.4
Mn1
meningioma 1
chr17_+_72918298 0.520 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr4_+_130055010 0.517 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chrX_+_10485121 0.515 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr8_+_45658273 0.515 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr11_+_60699758 0.513 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr3_+_89436699 0.503 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr11_-_106160708 0.482 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr11_-_106159902 0.481 ENSMUST00000064545.4
Limd2
LIM domain containing 2
chrX_+_136270302 0.462 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_+_120431770 0.461 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr4_-_134245579 0.461 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr19_+_4097392 0.456 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr7_+_82867327 0.452 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr18_-_52529847 0.451 ENSMUST00000171470.1
Lox
lysyl oxidase
chr7_+_110221697 0.444 ENSMUST00000033325.7
Swap70
SWA-70 protein
chr9_-_20898592 0.435 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr6_+_108660772 0.425 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr11_-_3504766 0.418 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr1_+_152399824 0.410 ENSMUST00000044311.8
Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr7_-_89517576 0.409 ENSMUST00000041761.5
Prss23
protease, serine, 23
chr11_-_69413675 0.404 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr5_+_92683625 0.387 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr18_-_52529692 0.383 ENSMUST00000025409.7
Lox
lysyl oxidase
chr17_+_34597852 0.364 ENSMUST00000174496.2
ENSMUST00000015596.3
ENSMUST00000173992.1
Ager


advanced glycosylation end product-specific receptor


chrX_-_7898864 0.363 ENSMUST00000154552.1
Pqbp1
polyglutamine binding protein 1
chr3_+_89436736 0.362 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr2_+_119547697 0.360 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chrX_+_136270253 0.344 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr15_-_98728120 0.341 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr4_+_116221633 0.340 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr4_+_126677630 0.339 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chrX_+_136707976 0.336 ENSMUST00000055104.5
Tceal1
transcription elongation factor A (SII)-like 1
chr11_+_69846610 0.331 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr7_+_83755904 0.325 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr5_-_24445166 0.311 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chrX_-_7898950 0.311 ENSMUST00000115655.1
ENSMUST00000156741.1
Pqbp1

polyglutamine binding protein 1

chr4_-_129742275 0.288 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr2_+_155940728 0.285 ENSMUST00000109629.1
Gm15557
predicted gene 15557
chr18_-_84086379 0.262 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr4_+_117835387 0.261 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_-_133801031 0.257 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr3_-_146839365 0.255 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr7_+_141216626 0.249 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chrX_+_101383726 0.246 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr11_-_115419917 0.244 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr5_-_124352233 0.243 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr15_-_103366763 0.236 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr8_+_95825353 0.234 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr3_+_36552600 0.221 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chrX_-_72274747 0.219 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr7_+_101394361 0.217 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr9_-_21852603 0.214 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr11_-_26591729 0.213 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr7_-_45052865 0.211 ENSMUST00000057293.6
Prr12
proline rich 12
chr9_+_21424984 0.207 ENSMUST00000172482.1
ENSMUST00000174050.1
Dnm2

dynamin 2

chr17_-_35162969 0.206 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr8_-_41016749 0.202 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr7_+_127485221 0.198 ENSMUST00000048896.6
Fbrs
fibrosin
chr6_+_147032528 0.192 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chr14_+_50944499 0.192 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr5_+_19907774 0.182 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_31168587 0.181 ENSMUST00000036618.7
Stab1
stabilin 1
chr13_-_115090123 0.170 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr5_-_24445254 0.161 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr2_+_128967383 0.161 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr7_+_101421691 0.160 ENSMUST00000163751.2
ENSMUST00000084894.7
ENSMUST00000166652.1
Pde2a


phosphodiesterase 2A, cGMP-stimulated


chr11_-_102319093 0.154 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf


upstream binding transcription factor, RNA polymerase I


chr15_-_93336800 0.138 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr9_+_57940104 0.132 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr7_-_119895697 0.125 ENSMUST00000059851.6
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr14_+_64950037 0.122 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr10_+_18845071 0.120 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr7_+_101361250 0.115 ENSMUST00000137384.1
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr15_+_102102926 0.114 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr11_+_69846665 0.105 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr9_+_13621646 0.097 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chr19_+_4231899 0.095 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr11_+_4637734 0.095 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr9_-_105521147 0.092 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr11_+_97663366 0.089 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_+_65537267 0.082 ENSMUST00000122141.1
Ube2k
ubiquitin-conjugating enzyme E2K
chr11_+_115420059 0.078 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr12_+_13269111 0.078 ENSMUST00000042953.8
Nbas
neuroblastoma amplified sequence
chr3_-_116968827 0.062 ENSMUST00000119557.1
Palmd
palmdelphin
chr7_+_141949982 0.058 ENSMUST00000105989.2
ENSMUST00000075528.5
ENSMUST00000174499.1
Brsk2


BR serine/threonine kinase 2


chr1_-_45503282 0.044 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr9_+_106429537 0.039 ENSMUST00000059802.6
Rpl29
ribosomal protein L29
chr7_+_119895836 0.037 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr11_+_53433299 0.028 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr5_-_92278155 0.024 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr4_+_118621160 0.008 ENSMUST00000147373.1
Ebna1bp2
EBNA1 binding protein 2
chr11_+_115420138 0.002 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr9_-_57552760 0.001 ENSMUST00000034856.8
Mpi
mannose phosphate isomerase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.8 15.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.6 3.2 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.5 1.5 GO:0015889 cobalamin transport(GO:0015889)
0.5 1.9 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.3 1.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657) cellular response to potassium ion starvation(GO:0051365)
0.3 1.4 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) proprioception(GO:0019230)
0.3 1.9 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 1.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 1.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 0.7 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 1.1 GO:0021764 amygdala development(GO:0021764)
0.2 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 1.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 0.6 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 3.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 2.7 GO:0030903 notochord development(GO:0030903)
0.1 1.0 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 3.0 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.4 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 1.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 1.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.5 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 1.4 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.4 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 8.5 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 1.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 0.6 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.1 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 1.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 1.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 2.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 2.3 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.8 GO:0021766 hippocampus development(GO:0021766)
0.0 0.6 GO:0003341 cilium movement(GO:0003341)
0.0 2.8 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.4 GO:0060074 synapse maturation(GO:0060074)
0.0 0.5 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.3 21.8 GO:0000786 nucleosome(GO:0000786)
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.2 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.1 3.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 6.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0050436 microfibril binding(GO:0050436)
0.4 3.2 GO:0001972 retinoic acid binding(GO:0001972)
0.3 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.2 3.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.0 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 15.4 GO:0042393 histone binding(GO:0042393)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 4.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.2 GO:0019955 cytokine binding(GO:0019955)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 4.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)