Motif ID: Smarcc1_Fosl1

Z-value: 0.754

Transcription factors associated with Smarcc1_Fosl1:

Gene SymbolEntrez IDGene Name
Fosl1 ENSMUSG00000024912.5 Fosl1
Smarcc1 ENSMUSG00000032481.10 Smarcc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smarcc1mm10_v2_chr9_+_110132015_110132102-0.373.5e-03Click!
Fosl1mm10_v2_chr19_+_5447692_54477110.373.6e-03Click!


Activity profile for motif Smarcc1_Fosl1.

activity profile for motif Smarcc1_Fosl1


Sorted Z-values histogram for motif Smarcc1_Fosl1

Sorted Z-values for motif Smarcc1_Fosl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Smarcc1_Fosl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_33907721 3.338 ENSMUST00000115161.1
ENSMUST00000062289.8
 Bend6

BEN domain containing 6

chr6_+_17463927 2.540 ENSMUST00000115442.1
 Met
met proto-oncogene
chr7_-_103827922 2.394 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr5_+_117841839 2.380 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr2_+_156475844 2.283 ENSMUST00000103135.1
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr9_-_20728219 2.278 ENSMUST00000034692.7
 Olfm2
olfactomedin 2
chr2_+_156475803 2.248 ENSMUST00000029155.8
 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr15_-_66812593 2.161 ENSMUST00000100572.3
 Sla
src-like adaptor
chr10_+_97565436 1.892 ENSMUST00000038160.4
 Lum
lumican
chr1_+_58210397 1.885 ENSMUST00000040442.5
 Aox4
aldehyde oxidase 4
chr17_+_55952623 1.864 ENSMUST00000003274.6
 Ebi3
Epstein-Barr virus induced gene 3
chr3_-_88503187 1.855 ENSMUST00000120377.1
 Lmna
lamin A
chr10_-_76725978 1.748 ENSMUST00000001147.4
 Col6a1
collagen, type VI, alpha 1
chr17_-_24644933 1.746 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr15_-_33687840 1.628 ENSMUST00000042021.3
 Tspyl5
testis-specific protein, Y-encoded-like 5
chr10_-_117282262 1.573 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr3_+_101377074 1.553 ENSMUST00000043983.5
 Igsf3
immunoglobulin superfamily, member 3
chr1_-_134235420 1.546 ENSMUST00000038191.6
ENSMUST00000086465.4
 Adora1

adenosine A1 receptor

chr7_+_30413744 1.542 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr3_-_88503331 1.509 ENSMUST00000029699.6
 Lmna
lamin A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 453 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.8 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 3.7 GO:0034605 cellular response to heat(GO:0034605)
0.8 3.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 3.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.7 3.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.7 2.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 2.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 2.6 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.4 2.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 2.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 2.5 GO:0035456 response to interferon-beta(GO:0035456)
0.1 2.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.4 2.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.2 2.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 2.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.5 2.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 1.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 1.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 192 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 5.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 4.9 GO:0005581 collagen trimer(GO:0005581)
0.0 4.0 GO:0005768 endosome(GO:0005768)
0.1 3.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 3.6 GO:0005604 basement membrane(GO:0005604)
0.5 3.4 GO:0005638 lamin filament(GO:0005638)
0.1 3.0 GO:0031430 M band(GO:0031430)
0.1 3.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 2.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 2.9 GO:0097060 synaptic membrane(GO:0097060)
0.2 2.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 2.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.6 2.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.5 2.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 1.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 1.9 GO:0032279 asymmetric synapse(GO:0032279)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 295 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
1.0 3.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 3.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 2.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 2.7 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 2.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.5 GO:0051787 misfolded protein binding(GO:0051787)
0.8 2.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 2.4 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.4 GO:0005516 calmodulin binding(GO:0005516)
0.7 2.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.3 2.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.1 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)