Motif ID: Snai1_Zeb1_Snai2
Z-value: 2.449



Transcription factors associated with Snai1_Zeb1_Snai2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Snai1 | ENSMUSG00000042821.7 | Snai1 |
Snai2 | ENSMUSG00000022676.6 | Snai2 |
Zeb1 | ENSMUSG00000024238.7 | Zeb1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zeb1 | mm10_v2_chr18_+_5591860_5591902 | -0.81 | 8.7e-15 | Click! |
Snai2 | mm10_v2_chr16_+_14705832_14705858 | -0.23 | 7.3e-02 | Click! |
Snai1 | mm10_v2_chr2_+_167538192_167538210 | 0.03 | 8.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 870 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 49.1 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
5.4 | 38.1 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
1.5 | 33.5 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
0.4 | 28.6 | GO:0030032 | lamellipodium assembly(GO:0030032) |
7.8 | 23.3 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
1.0 | 20.5 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
1.8 | 20.1 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.7 | 20.1 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
4.3 | 17.0 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
1.9 | 17.0 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
3.3 | 16.5 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
0.6 | 15.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
1.0 | 15.4 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
2.5 | 15.2 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
0.8 | 15.2 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
0.6 | 15.1 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
0.4 | 14.5 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
1.5 | 13.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
2.3 | 13.6 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
1.0 | 13.6 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 314 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 82.2 | GO:0043195 | terminal bouton(GO:0043195) |
0.4 | 79.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
1.7 | 52.3 | GO:0033268 | node of Ranvier(GO:0033268) |
1.0 | 48.5 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
1.5 | 38.1 | GO:0001891 | phagocytic cup(GO:0001891) |
1.4 | 27.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.3 | 27.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.2 | 26.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.3 | 26.7 | GO:0030427 | site of polarized growth(GO:0030427) |
0.4 | 25.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.4 | 21.2 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
0.5 | 19.8 | GO:0044295 | axonal growth cone(GO:0044295) |
0.6 | 19.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.2 | 19.5 | GO:0070382 | exocytic vesicle(GO:0070382) |
1.1 | 18.9 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
1.8 | 18.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.8 | 15.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
2.6 | 15.7 | GO:0061689 | tricellular tight junction(GO:0061689) |
1.2 | 15.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.2 | 14.3 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 518 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 35.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
1.0 | 35.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 32.1 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
1.1 | 30.7 | GO:0004027 | alcohol sulfotransferase activity(GO:0004027) |
3.0 | 30.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.9 | 28.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
1.1 | 27.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 25.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
1.0 | 24.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.3 | 22.1 | GO:0005518 | collagen binding(GO:0005518) |
3.1 | 21.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.5 | 21.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
1.2 | 21.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
1.1 | 20.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
1.3 | 19.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.2 | 19.0 | GO:0030165 | PDZ domain binding(GO:0030165) |
1.3 | 18.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
1.4 | 17.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
1.6 | 17.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.3 | 17.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |