Motif ID: Sox11

Z-value: 0.302


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.462.9e-04Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_84064772 1.709 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr9_-_16378231 1.436 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr2_-_79456750 1.302 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr9_+_89909775 1.115 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr5_+_14514918 1.049 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chrX_+_85574018 0.957 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr5_-_131616599 0.949 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr13_-_41487306 0.942 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chrX_+_166344692 0.894 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr13_-_99516537 0.823 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr1_+_82233112 0.823 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr11_+_24080664 0.813 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr6_-_60829826 0.760 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr4_+_21848039 0.703 ENSMUST00000098238.2
ENSMUST00000108229.1
 Sfrs18

serine/arginine-rich splicing factor 18

chr16_-_50330987 0.676 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr8_-_34965631 0.595 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr5_+_89027959 0.587 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr7_-_73541738 0.536 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr4_-_97584612 0.513 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 0.468 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_-_123141067 0.442 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr6_-_136173492 0.414 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chrX_-_37104523 0.412 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr17_-_29007925 0.405 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr9_+_107888129 0.380 ENSMUST00000035202.2
 Mon1a
MON1 homolog A (yeast)
chr11_-_69369377 0.360 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr5_+_64812336 0.357 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr16_-_38341812 0.331 ENSMUST00000114740.2
ENSMUST00000023501.8
 Maats1

MYCBP-associated, testis expressed 1

chr4_+_59003121 0.330 ENSMUST00000095070.3
ENSMUST00000174664.1
 Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr11_+_69364010 0.326 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chr2_-_36136773 0.324 ENSMUST00000028251.3
 Rbm18
RNA binding motif protein 18
chr8_-_83442648 0.322 ENSMUST00000167525.1
 Scoc
short coiled-coil protein
chr9_+_101074727 0.296 ENSMUST00000085177.3
 Msl2
male-specific lethal 2 homolog (Drosophila)
chr10_-_76110956 0.279 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr12_+_8921598 0.272 ENSMUST00000020909.3
 Laptm4a
lysosomal-associated protein transmembrane 4A
chr14_-_52213379 0.265 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr16_+_8830093 0.260 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr1_-_175491130 0.248 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7
chr9_+_32116040 0.247 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr10_+_119992916 0.238 ENSMUST00000105261.2
 Grip1
glutamate receptor interacting protein 1
chr5_-_148552783 0.203 ENSMUST00000079324.7
ENSMUST00000164904.1
 Ubl3

ubiquitin-like 3

chr10_-_14718191 0.193 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr17_+_43016536 0.191 ENSMUST00000024708.4
 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr5_+_89028035 0.191 ENSMUST00000113216.2
ENSMUST00000134303.1
 Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr4_-_44072578 0.185 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr2_-_127792467 0.184 ENSMUST00000135091.1
 1500011K16Rik
RIKEN cDNA 1500011K16 gene
chr12_-_54862783 0.169 ENSMUST00000078124.7
 Cfl2
cofilin 2, muscle
chr10_+_24869982 0.164 ENSMUST00000092646.6
 Med23
mediator complex subunit 23
chr16_+_65520503 0.138 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
 Pou1f1


POU domain, class 1, transcription factor 1


chr2_+_15055274 0.134 ENSMUST00000069870.3
 Arl5b
ADP-ribosylation factor-like 5B
chr6_-_42693087 0.131 ENSMUST00000121083.1
 Fam115a
family with sequence similarity 115, member A
chr17_+_35517100 0.127 ENSMUST00000164242.2
ENSMUST00000045956.7
 Cchcr1

coiled-coil alpha-helical rod protein 1

chr5_+_144100387 0.123 ENSMUST00000041804.7
 Lmtk2
lemur tyrosine kinase 2
chr13_+_40859768 0.115 ENSMUST00000110191.2
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr7_-_55962466 0.107 ENSMUST00000032635.7
ENSMUST00000152649.1
 Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr2_-_36136602 0.105 ENSMUST00000122456.1
 Rbm18
RNA binding motif protein 18
chr6_-_42693030 0.096 ENSMUST00000045140.4
 Fam115a
family with sequence similarity 115, member A
chr8_+_85432686 0.082 ENSMUST00000180883.1
 1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr10_+_90576252 0.079 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
 Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr1_+_44119952 0.073 ENSMUST00000114709.2
 Bivm
basic, immunoglobulin-like variable motif containing
chr15_-_81104999 0.069 ENSMUST00000109579.2
 Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr15_+_76797628 0.066 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr1_-_162866502 0.061 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr2_-_86347764 0.060 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr9_-_51102062 0.058 ENSMUST00000170947.1
 4833427G06Rik
RIKEN cDNA 4833427G06 gene
chr5_+_15516489 0.057 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr11_+_4873951 0.054 ENSMUST00000038570.2
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr5_+_121795034 0.050 ENSMUST00000162327.1
 Atxn2
ataxin 2
chr16_-_17911303 0.044 ENSMUST00000003621.8
 Dgcr14
DiGeorge syndrome critical region gene 14
chr9_+_52047150 0.041 ENSMUST00000163153.1
 Rdx
radixin
chr13_+_24327415 0.030 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr2_-_156111954 0.029 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
 Cpne1

Rbm12



copine I

RNA binding motif protein 12




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.3 0.9 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.6 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.2 1.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 1.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)