Motif ID: Sox11

Z-value: 0.302


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.462.9e-04Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_84064772 1.709 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr9_-_16378231 1.436 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr2_-_79456750 1.302 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr9_+_89909775 1.115 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr5_+_14514918 1.049 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chrX_+_85574018 0.957 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr5_-_131616599 0.949 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr13_-_41487306 0.942 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chrX_+_166344692 0.894 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr13_-_99516537 0.823 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr1_+_82233112 0.823 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr11_+_24080664 0.813 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr6_-_60829826 0.760 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr4_+_21848039 0.703 ENSMUST00000098238.2
ENSMUST00000108229.1
 Sfrs18

serine/arginine-rich splicing factor 18

chr16_-_50330987 0.676 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr8_-_34965631 0.595 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr5_+_89027959 0.587 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr7_-_73541738 0.536 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr4_-_97584612 0.513 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 0.468 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.4 GO:0010842 retina layer formation(GO:0010842)
0.3 1.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.3 0.9 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.6 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.3 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)