Motif ID: Sox13

Z-value: 0.311


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_133424404-0.462.2e-04Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 5.540 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_+_96210107 2.459 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr18_+_69593361 1.804 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr7_-_121035096 1.549 ENSMUST00000065740.2
 Gm9905
predicted gene 9905
chr1_+_17145357 1.018 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr18_+_64887690 0.993 ENSMUST00000163516.1
 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr1_+_19103022 0.984 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr9_-_75597643 0.956 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr5_-_8367982 0.872 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
 Adam22






a disintegrin and metallopeptidase domain 22






chr19_-_19001099 0.764 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr1_-_93101825 0.638 ENSMUST00000112958.2
 Kif1a
kinesin family member 1A
chr13_-_66851513 0.561 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr18_+_37355271 0.561 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr8_-_11008458 0.552 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr15_-_50890396 0.347 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr3_+_60501252 0.343 ENSMUST00000099087.2
 Mbnl1
muscleblind-like 1 (Drosophila)
chr13_-_66852017 0.329 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr1_+_135729147 0.312 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr7_+_24271568 0.257 ENSMUST00000032696.6
 Zfp93
zinc finger protein 93
chr10_-_116473418 0.250 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr14_-_47568427 0.205 ENSMUST00000042988.6
 Atg14
autophagy related 14
chr1_+_39900883 0.168 ENSMUST00000163854.2
ENSMUST00000168431.1
 Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr4_+_103143052 0.136 ENSMUST00000106855.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr15_-_91049823 0.114 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
 Kif21a




kinesin family member 21A




chr3_-_96058446 0.114 ENSMUST00000015891.5
 Vps45
vacuolar protein sorting 45 (yeast)
chr6_-_56362356 0.113 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
 Pde1c



phosphodiesterase 1C



chr3_-_141982224 0.110 ENSMUST00000029948.8
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr11_-_77489666 0.094 ENSMUST00000037593.7
ENSMUST00000092892.3
 Ankrd13b

ankyrin repeat domain 13b

chr2_-_36104060 0.081 ENSMUST00000112961.3
ENSMUST00000112966.3
 Lhx6

LIM homeobox protein 6

chr7_-_105787567 0.069 ENSMUST00000144189.1
 Dchs1
dachsous 1 (Drosophila)
chr7_-_132813095 0.064 ENSMUST00000106165.1
 Fam53b
family with sequence similarity 53, member B
chr14_-_121698417 0.048 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr1_+_160906372 0.029 ENSMUST00000161609.1
 Rc3h1
RING CCCH (C3H) domains 1
chr16_-_28929658 0.022 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 5.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.0 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.2 1.8 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.6 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.9 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.0 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 1.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.0 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 5.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)