Motif ID: Sox14

Z-value: 1.011


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_998761930.211.2e-01Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_14523178 12.907 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr11_+_67586520 9.019 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr17_-_79355082 8.112 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr11_+_24076529 7.940 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr11_+_67586675 7.684 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr7_-_19166119 7.235 ENSMUST00000094790.3
 Gipr
gastric inhibitory polypeptide receptor
chr7_+_96210107 6.542 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr18_-_43393346 6.225 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr4_+_13751297 6.013 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_43059418 5.786 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr8_-_84773381 5.614 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr9_+_58554799 5.458 ENSMUST00000098676.2
 Gm10657
predicted gene 10657
chr8_-_105289465 5.275 ENSMUST00000171788.1
ENSMUST00000014981.6
 4931428F04Rik

RIKEN cDNA 4931428F04 gene

chr5_-_38159457 5.022 ENSMUST00000031009.4
 Nsg1
neuron specific gene family member 1
chr1_-_12991109 4.978 ENSMUST00000115403.2
ENSMUST00000115402.1
 Slco5a1

solute carrier organic anion transporter family, member 5A1

chr3_+_101377074 4.935 ENSMUST00000043983.5
 Igsf3
immunoglobulin superfamily, member 3
chr13_-_34130345 4.699 ENSMUST00000075774.3
 Tubb2b
tubulin, beta 2B class IIB
chr2_-_85196697 4.660 ENSMUST00000099930.2
ENSMUST00000111601.1
 Lrrc55

leucine rich repeat containing 55

chr3_+_55461758 4.646 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr14_+_64589802 4.500 ENSMUST00000180610.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.0 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 12.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.4 9.4 GO:0008340 determination of adult lifespan(GO:0008340)
2.8 8.3 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.7 8.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
2.0 8.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 7.2 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
1.6 6.5 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 6.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 6.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 6.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 5.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.8 5.8 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.4 5.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 5.2 GO:0030509 BMP signaling pathway(GO:0030509)
0.5 5.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.4 5.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 5.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 4.9 GO:0032808 lacrimal gland development(GO:0032808)
0.2 4.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 18.4 GO:0005884 actin filament(GO:0005884)
0.0 14.5 GO:0015629 actin cytoskeleton(GO:0015629)
2.0 8.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 7.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 6.8 GO:0001726 ruffle(GO:0001726)
0.1 5.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 5.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 5.2 GO:0016607 nuclear speck(GO:0016607)
0.8 5.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 5.1 GO:0030027 lamellipodium(GO:0030027)
0.1 5.1 GO:0042641 actomyosin(GO:0042641)
0.1 5.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 4.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 4.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 4.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.4 4.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 4.0 GO:0070938 contractile ring(GO:0070938)
0.8 3.9 GO:0030314 junctional membrane complex(GO:0030314)
0.1 3.6 GO:0043034 costamere(GO:0043034)
0.3 3.4 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.6 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.1 16.0 GO:0051015 actin filament binding(GO:0051015)
2.8 8.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.4 8.1 GO:0017049 GTP-Rho binding(GO:0017049)
1.0 8.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 7.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 7.2 GO:0017046 peptide hormone binding(GO:0017046)
0.2 6.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
1.3 6.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.6 6.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 5.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.3 5.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 5.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.8 5.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 5.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.4 4.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 4.4 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.2 4.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 4.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 4.3 GO:0004364 glutathione transferase activity(GO:0004364)