Motif ID: Sox15

Z-value: 0.727


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 111 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_53596936 7.694 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr11_-_106715251 6.236 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr8_-_11312731 6.207 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr14_-_48662740 5.791 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr6_-_23248264 5.788 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr19_+_55741810 5.596 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr18_+_82554463 5.541 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr7_-_49636847 5.392 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_-_119238794 5.079 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr17_-_70851189 4.892 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr2_-_170406501 4.622 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr2_-_84425258 4.512 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr11_+_88068242 4.423 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr12_+_24708984 4.298 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr3_+_37639985 3.781 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chr18_+_11633276 3.725 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr10_-_37138863 3.456 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr3_-_8964037 3.303 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr15_+_25622525 3.292 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr2_+_32535315 3.244 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 7.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724)
1.6 6.2 GO:0050904 diapedesis(GO:0050904)
0.9 6.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
1.4 5.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.0 5.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 5.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 5.5 GO:0042552 myelination(GO:0042552)
0.3 5.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 5.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.3 4.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.1 4.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
1.1 4.3 GO:1904192 prostate gland stromal morphogenesis(GO:0060741) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.4 4.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 4.2 GO:0001885 endothelial cell development(GO:0001885)
0.8 3.8 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.7 3.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 3.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.6 3.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.8 3.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.8 8.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 8.1 GO:0000790 nuclear chromatin(GO:0000790)
1.2 6.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.2 6.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.7 5.5 GO:0033269 internode region of axon(GO:0033269)
0.2 5.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.4 4.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 4.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.1 4.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.9 4.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 3.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.6 GO:0030426 growth cone(GO:0030426)
1.2 3.5 GO:0042585 germinal vesicle(GO:0042585)
0.1 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 3.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 2.8 GO:0043034 costamere(GO:0043034)
0.5 2.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.4 GO:0097386 glial cell projection(GO:0097386)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.4 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.7 8.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 6.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 6.1 GO:0042393 histone binding(GO:0042393)
0.3 5.6 GO:0045295 gamma-catenin binding(GO:0045295)
1.4 5.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 4.9 GO:0008432 JUN kinase binding(GO:0008432)
1.1 4.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.9 4.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 4.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 3.8 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.4 3.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 3.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.3 GO:0030507 spectrin binding(GO:0030507)
0.2 3.2 GO:0035198 miRNA binding(GO:0035198)
0.0 2.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.5 2.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 2.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.8 2.4 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)