Motif ID: Sox17

Z-value: 0.712


Transcription factors associated with Sox17:

Gene SymbolEntrez IDGene Name
Sox17 ENSMUSG00000025902.7 Sox17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496363_4496389-0.264.6e-02Click!


Activity profile for motif Sox17.

activity profile for motif Sox17


Sorted Z-values histogram for motif Sox17

Sorted Z-values for motif Sox17



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox17

PNG image of the network

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Top targets:


Showing 1 to 20 of 78 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 17.174 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_+_52008210 8.556 ENSMUST00000027277.5
 Stat4
signal transducer and activator of transcription 4
chr2_-_180889660 7.639 ENSMUST00000137629.1
 Gm14342
predicted gene 14342
chr14_+_50944499 6.341 ENSMUST00000178092.1
 Pnp
purine-nucleoside phosphorylase
chr8_-_105471481 6.228 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr11_-_11970540 5.753 ENSMUST00000109653.1
 Grb10
growth factor receptor bound protein 10
chr10_-_128176568 4.850 ENSMUST00000092033.2
 Rbms2
RNA binding motif, single stranded interacting protein 2
chr19_+_55741810 4.620 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr6_-_148944750 4.293 ENSMUST00000111562.1
ENSMUST00000081956.5
 Fam60a

family with sequence similarity 60, member A

chr12_+_24708241 3.957 ENSMUST00000020980.5
 Rrm2
ribonucleotide reductase M2
chr4_+_41903610 3.663 ENSMUST00000098128.3
 Gm21541
predicted gene, 21541
chr10_+_11609256 3.429 ENSMUST00000052902.7
 Gm9797
predicted pseudogene 9797
chr15_+_85205949 3.017 ENSMUST00000057410.7
ENSMUST00000109432.3
 Fbln1

fibulin 1

chr1_+_135729147 2.760 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr2_-_127133909 2.627 ENSMUST00000110387.3
 Ncaph
non-SMC condensin I complex, subunit H
chr13_+_54071815 2.592 ENSMUST00000021930.8
 Sfxn1
sideroflexin 1
chr4_-_42773993 2.532 ENSMUST00000095114.4
 Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr14_+_31134853 2.440 ENSMUST00000090212.4
 Nt5dc2
5'-nucleotidase domain containing 2
chr7_-_100656953 2.435 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
 Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr8_+_69822429 2.420 ENSMUST00000164890.1
ENSMUST00000034325.4
 Lpar2

lysophosphatidic acid receptor 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 17.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 8.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
2.1 6.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 6.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.6 5.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.6 4.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 4.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.4 4.0 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
1.0 3.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 2.8 GO:0070527 platelet aggregation(GO:0070527)
0.2 2.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 2.6 GO:0006826 iron ion transport(GO:0006826)
0.2 2.5 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.2 2.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.8 2.4 GO:0006553 lysine metabolic process(GO:0006553)
0.1 2.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 2.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.2 GO:0050957 equilibrioception(GO:0050957)
0.0 2.2 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 1.9 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 4.3 GO:0016580 Sin3 complex(GO:0016580)
0.8 4.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 4.0 GO:0001669 acrosomal vesicle(GO:0001669)
1.0 3.0 GO:0071953 fibrinogen complex(GO:0005577) elastic fiber(GO:0071953)
0.4 2.6 GO:0000796 condensin complex(GO:0000796)
0.0 2.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.1 1.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.3 GO:0034464 BBSome(GO:0034464)
0.1 1.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.4 1.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 1.1 GO:1990462 omegasome(GO:1990462)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 17.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 8.5 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
2.1 6.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 5.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 4.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 4.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 3.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 2.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.5 GO:0015485 cholesterol binding(GO:0015485)
0.8 2.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.6 2.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 2.4 GO:0008494 translation activator activity(GO:0008494)
0.2 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.8 2.3 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.4 1.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.4 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.5 1.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)