Z-value: 3.069
Transcription factors associated with Sox2:
Activity-expression correlation:
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Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 405 entries
Log-likelihood per target Total log-likelihood Term Description
4.6
104.7
GO:0021819 layer formation in cerebral cortex(GO:0021819)
3.3
52.4
GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
3.7
40.8
GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.3
39.2
GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.5
36.9
GO:0000045 autophagosome assembly(GO:0000045)
2.3
36.7
GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2
32.6
GO:0007018 microtubule-based movement(GO:0007018)
0.9
31.9
GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
9.8
29.4
GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.7
28.1
GO:0006376 mRNA splice site selection(GO:0006376)
1.4
26.5
GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
5.2
25.9
GO:0031022 nuclear migration along microfilament(GO:0031022)
0.4
24.0
GO:0021954 central nervous system neuron development(GO:0021954)
4.6
23.2
GO:0046684 response to pyrethroid(GO:0046684)
1.1
21.5
GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3
20.9
GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
2.3
20.7
GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.4
20.3
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.4
19.6
GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2
19.3
GO:0010506 regulation of autophagy(GO:0010506)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 168 entries
Log-likelihood per target Total log-likelihood Term Description
0.3
89.8
GO:0005874 microtubule(GO:0005874)
2.5
61.5
GO:0071565 nBAF complex(GO:0071565)
4.9
48.9
GO:0045298 tubulin complex(GO:0045298)
0.5
41.1
GO:0043198 dendritic shaft(GO:0043198)
2.0
40.8
GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6
37.9
GO:0034704 calcium channel complex(GO:0034704)
1.6
36.6
GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
3.7
33.6
GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
2.9
32.4
GO:0031258 lamellipodium membrane(GO:0031258)
3.1
30.6
GO:0044327 dendritic spine head(GO:0044327)
0.6
27.0
GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4
26.0
GO:0005871 kinesin complex(GO:0005871)
0.2
24.6
GO:0005923 bicellular tight junction(GO:0005923)
0.5
23.6
GO:0031941 filamentous actin(GO:0031941)
1.4
23.2
GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.9
22.9
GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5
22.5
GO:0044295 axonal growth cone(GO:0044295)
0.4
22.3
GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4
22.2
GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5
21.0
GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 265 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
81.2
GO:0008270 zinc ion binding(GO:0008270)
0.2
74.0
GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
2.7
65.2
GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1
63.9
GO:0044822 poly(A) RNA binding(GO:0044822)
0.4
62.1
GO:0008017 microtubule binding(GO:0008017)
2.5
54.1
GO:0034185 apolipoprotein binding(GO:0034185)
1.1
53.0
GO:0045499 chemorepellent activity(GO:0045499)
1.8
52.8
GO:0008093 cytoskeletal adaptor activity(GO:0008093)
5.2
41.5
GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.0
33.9
GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5
32.5
GO:0003777 microtubule motor activity(GO:0003777)
0.6
28.8
GO:0070888 E-box binding(GO:0070888)
1.3
28.2
GO:0001784 phosphotyrosine binding(GO:0001784)
0.5
27.6
GO:0048365 Rac GTPase binding(GO:0048365)
0.8
27.1
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2
25.7
GO:0017124 SH3 domain binding(GO:0017124)
0.7
25.5
GO:0004364 glutathione transferase activity(GO:0004364)
0.4
24.6
GO:0005200 structural constituent of cytoskeleton(GO:0005200)
3.4
23.8
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.1
23.2
GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
