Motif ID: Sox2

Z-value: 3.069


Transcription factors associated with Sox2:

Gene SymbolEntrez IDGene Name
Sox2 ENSMUSG00000074637.4 Sox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox2mm10_v2_chr3_+_34649987_34650005-0.522.1e-05Click!


Activity profile for motif Sox2.

activity profile for motif Sox2


Sorted Z-values histogram for motif Sox2

Sorted Z-values for motif Sox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_143933089 33.209 ENSMUST00000087313.3
Dcx
doublecortin
chrX_-_143933204 31.980 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr17_-_79355082 30.888 ENSMUST00000068958.7
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr11_-_98329641 27.779 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr10_+_80300997 27.256 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr10_+_29143996 26.294 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr10_-_29144194 24.003 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr1_+_136131382 23.583 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr10_-_84440591 18.319 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr8_-_33747724 17.555 ENSMUST00000179364.1
Smim18
small integral membrane protein 18
chr7_+_99466004 17.397 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr5_-_22344690 17.381 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr1_+_34579693 17.005 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chr4_-_129121889 16.516 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr4_+_43406435 16.361 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr12_-_31713873 15.761 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr11_+_58948890 15.693 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr4_-_20778527 15.624 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr7_-_74013676 15.258 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_-_69184177 15.203 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr18_+_37484955 15.178 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr5_+_111417263 14.930 ENSMUST00000094463.4
Mn1
meningioma 1
chr7_-_25005895 14.857 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr1_-_12991109 14.326 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr8_+_45507768 14.282 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr4_-_148130678 14.190 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr10_-_122047293 14.134 ENSMUST00000020322.5
ENSMUST00000081688.6
Srgap1

SLIT-ROBO Rho GTPase activating protein 1

chr7_+_29303938 13.911 ENSMUST00000108231.1
Dpf1
D4, zinc and double PHD fingers family 1
chr7_+_29303958 13.569 ENSMUST00000049977.6
Dpf1
D4, zinc and double PHD fingers family 1
chr11_+_24076529 13.465 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr18_-_43059418 13.319 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr2_+_155381808 13.128 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr8_+_34807287 13.027 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr2_-_160367057 13.021 ENSMUST00000099126.3
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr5_+_37245792 12.952 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1
chr8_+_123411424 12.849 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr2_+_55437100 12.714 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr19_+_44992127 12.693 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr15_-_75905349 12.646 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr10_+_127165118 12.589 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr4_+_48585276 12.502 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_104231390 12.432 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr5_-_114091358 12.419 ENSMUST00000150106.1
Svop
SV2 related protein
chr9_+_108826320 12.394 ENSMUST00000024238.5
Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr4_+_48585193 12.231 ENSMUST00000107703.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_-_84773381 12.214 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr1_+_66322102 12.190 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr2_-_156312470 12.166 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr8_-_109251698 12.119 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr11_+_104231573 12.036 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chrX_+_48519245 12.027 ENSMUST00000033430.2
Rab33a
RAB33A, member of RAS oncogene family
chr2_+_37516618 11.997 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr5_+_88583527 11.989 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr10_+_69706326 11.862 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr5_-_131538687 11.837 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr4_+_48585135 11.753 ENSMUST00000030032.6
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_13839916 11.725 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr2_-_65567505 11.685 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr9_+_102718424 11.582 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr2_-_65567465 11.501 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_-_81025406 11.469 ENSMUST00000055125.4
Diras1
DIRAS family, GTP-binding RAS-like 1
chr7_-_47132698 11.458 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr6_+_51432663 11.241 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr3_-_123690806 11.224 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr9_+_59617284 11.184 ENSMUST00000026267.8
ENSMUST00000050483.7
Parp6

poly (ADP-ribose) polymerase family, member 6

chr5_-_38159457 11.051 ENSMUST00000031009.4
Nsg1
neuron specific gene family member 1
chr5_+_33983437 11.050 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr7_+_29309429 11.042 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr11_+_116918844 11.025 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr8_-_84237042 11.009 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr11_+_104231515 10.962 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr5_-_136244865 10.892 ENSMUST00000005188.9
Sh2b2
SH2B adaptor protein 2
chr6_+_17065129 10.879 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr11_+_80477015 10.848 ENSMUST00000053413.10
ENSMUST00000147694.1
Cdk5r1

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

chr16_-_18629864 10.751 ENSMUST00000096987.5
Sept5
septin 5
chr11_+_104231465 10.729 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr18_-_43393346 10.641 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr6_-_88875035 10.557 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr7_+_16944645 10.554 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr8_+_124793013 10.466 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr2_+_155382186 10.431 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr8_-_84937347 10.384 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr2_+_68861564 10.347 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr7_-_132317198 10.167 ENSMUST00000080215.5
Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_+_34549595 10.079 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr2_-_119271202 10.016 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr13_-_55488038 9.966 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
Dbn1


drebrin 1


chr8_+_124793061 9.966 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr7_+_99381495 9.942 ENSMUST00000037528.8
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
chr6_+_54681687 9.936 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr11_-_76468396 9.936 ENSMUST00000065028.7
Abr
active BCR-related gene
chr12_+_29528382 9.923 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr13_-_54749627 9.854 ENSMUST00000099506.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr17_-_35910032 9.844 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr19_-_46327121 9.783 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr3_-_95228636 9.720 ENSMUST00000065482.5
Mllt11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_+_95160449 9.716 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr17_-_25433263 9.694 ENSMUST00000159623.1
Cacna1h
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr1_+_62703667 9.669 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
Nrp2



neuropilin 2



chr8_-_83166170 9.598 ENSMUST00000098605.2
Gm10645
predicted gene 10645
chr5_+_33983534 9.589 ENSMUST00000114382.1
Gm1673
predicted gene 1673
chr10_+_43579161 9.565 ENSMUST00000058714.8
Cd24a
CD24a antigen
chrX_+_134295225 9.546 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chr4_+_116221590 9.545 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr8_-_122699066 9.544 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr1_-_87156127 9.488 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr1_+_66321708 9.486 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr3_+_102010138 9.416 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr3_-_108402589 9.401 ENSMUST00000147565.1
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr12_+_95692212 9.399 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr15_-_99705490 9.317 ENSMUST00000163472.2
Gm17349
predicted gene, 17349
chr1_+_132191436 9.253 ENSMUST00000112357.2
Lemd1
LEM domain containing 1
chr8_+_70863127 9.251 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr4_+_9269285 9.241 ENSMUST00000038841.7
Clvs1
clavesin 1
chr8_+_69808672 9.132 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr10_+_106470281 9.125 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr13_-_49147931 9.070 ENSMUST00000162581.1
ENSMUST00000110097.2
ENSMUST00000049265.8
ENSMUST00000035538.6
ENSMUST00000110096.1
ENSMUST00000091623.3
Wnk2





WNK lysine deficient protein kinase 2





chr11_+_67586520 8.942 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr5_+_35893319 8.906 ENSMUST00000064571.4
Afap1
actin filament associated protein 1
chr18_+_36939178 8.853 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr13_+_88821472 8.819 ENSMUST00000118731.1
ENSMUST00000081769.6
Edil3

EGF-like repeats and discoidin I-like domains 3

chr7_-_47133395 8.763 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr2_+_146221921 8.756 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr14_+_60378242 8.725 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr9_-_103761820 8.701 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr7_+_80860909 8.692 ENSMUST00000132163.1
ENSMUST00000147125.1
Zscan2

zinc finger and SCAN domain containing 2

chr16_+_18127607 8.611 ENSMUST00000059589.5
Rtn4r
reticulon 4 receptor
chr11_-_78497734 8.586 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr7_-_142095266 8.573 ENSMUST00000039926.3
Dusp8
dual specificity phosphatase 8
chr2_-_30474199 8.557 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr6_+_51432678 8.547 ENSMUST00000160133.1
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr6_-_88874597 8.545 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr1_-_64122256 8.499 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr11_-_78497458 8.487 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr5_+_3928033 8.486 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr2_+_32621750 8.426 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr15_-_39943963 8.400 ENSMUST00000110305.2
Lrp12
low density lipoprotein-related protein 12
chr4_-_149676043 8.338 ENSMUST00000118704.1
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr9_+_58554799 8.286 ENSMUST00000098676.2
Gm10657
predicted gene 10657
chr5_+_75574916 8.279 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr2_-_79456750 8.258 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr3_-_122619663 8.251 ENSMUST00000162409.1
Fnbp1l
formin binding protein 1-like
chr3_-_122619442 8.107 ENSMUST00000162947.1
Fnbp1l
formin binding protein 1-like
chr17_-_35909626 8.087 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr6_+_39873271 8.076 ENSMUST00000180886.1
Tmem178b
transmembrane protein 178B
chr15_+_82275197 8.048 ENSMUST00000116423.1
Sept3
septin 3
chr18_-_77565050 8.034 ENSMUST00000182153.1
ENSMUST00000182146.1
ENSMUST00000026494.7
ENSMUST00000182024.1
Rnf165



ring finger protein 165



chr2_-_113217051 8.032 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr2_+_65930117 8.019 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr18_-_23038656 8.015 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr10_+_69925766 7.981 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr1_+_17145357 7.978 ENSMUST00000026879.7
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr13_-_54749849 7.971 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr6_+_54039558 7.955 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr13_+_88821606 7.947 ENSMUST00000043111.6
Edil3
EGF-like repeats and discoidin I-like domains 3
chr6_-_18514802 7.946 ENSMUST00000090601.5
Cttnbp2
cortactin binding protein 2
chr6_+_61180313 7.945 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr16_+_13986596 7.937 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
2900011O08Rik


RIKEN cDNA 2900011O08 gene


chr11_+_67586675 7.910 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr2_-_77280589 7.896 ENSMUST00000102659.1
Sestd1
SEC14 and spectrin domains 1
chr19_-_4943049 7.869 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
Peli3


pellino 3


chr1_-_132390301 7.859 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr4_-_155043143 7.804 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr16_-_34513944 7.796 ENSMUST00000151491.1
ENSMUST00000114960.2
Kalrn

kalirin, RhoGEF kinase

chr2_+_163438455 7.792 ENSMUST00000109420.3
ENSMUST00000109421.3
ENSMUST00000018087.6
ENSMUST00000137070.1
Gdap1l1



ganglioside-induced differentiation-associated protein 1-like 1



chr10_-_83533383 7.784 ENSMUST00000146640.1
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr2_+_68861433 7.754 ENSMUST00000028426.2
Cers6
ceramide synthase 6
chr15_-_75566811 7.740 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr17_-_25433775 7.713 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr11_-_98022594 7.683 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
Cacnb1



calcium channel, voltage-dependent, beta 1 subunit



chr3_-_38484831 7.674 ENSMUST00000120875.1
Ankrd50
ankyrin repeat domain 50
chr16_+_20097554 7.651 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr1_+_6487231 7.636 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr2_+_4559742 7.636 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr12_+_71309876 7.592 ENSMUST00000061273.5
ENSMUST00000150639.1
Dact1

dapper homolog 1, antagonist of beta-catenin (xenopus)

chr5_+_3928267 7.575 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr8_+_123332676 7.555 ENSMUST00000010298.6
Spire2
spire homolog 2 (Drosophila)
chr10_+_69925954 7.545 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr2_-_152830615 7.540 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr7_+_126272589 7.495 ENSMUST00000056028.9
Sbk1
SH3-binding kinase 1
chr4_-_20778852 7.477 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr10_+_69925484 7.442 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr3_+_153973436 7.428 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr3_+_103576081 7.395 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
Syt6



synaptotagmin VI



chr16_+_17070220 7.391 ENSMUST00000141959.1
Ypel1
yippee-like 1 (Drosophila)
chr3_-_116968969 7.379 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr4_+_116221689 7.368 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr1_-_36557517 7.279 ENSMUST00000114990.1
ENSMUST00000128104.1
ENSMUST00000027295.4
Sema4c


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C


chr5_+_142702091 7.270 ENSMUST00000058418.7
Slc29a4
solute carrier family 29 (nucleoside transporters), member 4
chr17_+_80944611 7.265 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr17_+_52602700 7.243 ENSMUST00000039366.10
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr3_+_88621436 7.234 ENSMUST00000170653.2
ENSMUST00000177303.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr16_-_34514084 7.232 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr5_-_122779278 7.223 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr2_-_151973387 7.196 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr17_-_57087729 7.179 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr10_+_17723220 7.156 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr2_-_181599128 7.142 ENSMUST00000060173.8
Samd10
sterile alpha motif domain containing 10
chr7_-_16874845 7.132 ENSMUST00000181501.1
9330104G04Rik
RIKEN cDNA 9330104G04 gene
chr1_-_138842429 7.125 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
6.0 17.9 GO:0071929 alpha-tubulin acetylation(GO:0071929)
5.8 17.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
5.5 16.5 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
5.2 25.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
4.9 14.6 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
4.6 23.2 GO:0046684 response to pyrethroid(GO:0046684)
4.6 104.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
4.2 12.5 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
3.9 11.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
3.8 11.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
3.8 11.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
3.7 40.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.7 18.4 GO:2001025 positive regulation of response to drug(GO:2001025)
3.6 14.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
3.5 17.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
3.4 17.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
3.3 10.0 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
3.3 9.9 GO:0017085 response to insecticide(GO:0017085)
3.3 52.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
3.3 39.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
3.2 13.0 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
3.2 9.7 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) dorsal root ganglion development(GO:1990791)
3.2 16.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
3.2 9.6 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
3.1 18.7 GO:0006172 ADP biosynthetic process(GO:0006172)
3.0 11.9 GO:0046898 response to cycloheximide(GO:0046898)
2.9 11.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
2.8 11.3 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
2.8 8.5 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
2.7 10.9 GO:0001922 B-1 B cell homeostasis(GO:0001922)
2.6 7.9 GO:0007403 glial cell fate determination(GO:0007403)
2.6 15.6 GO:0061549 sympathetic ganglion development(GO:0061549)
2.5 7.6 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
2.5 7.6 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
2.5 12.6 GO:0030259 lipid glycosylation(GO:0030259)
2.5 12.4 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
2.5 7.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
2.4 19.6 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.4 12.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
2.4 9.5 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
2.4 7.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
2.4 9.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
2.3 20.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
2.3 36.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
2.3 4.6 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
2.3 4.5 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
2.3 9.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
2.3 9.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
2.2 6.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.1 8.3 GO:1990743 protein sialylation(GO:1990743)
2.1 8.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.9 13.3 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.8 7.4 GO:0034214 protein hexamerization(GO:0034214)
1.8 7.2 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.7 5.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.7 17.3 GO:0007379 segment specification(GO:0007379)
1.6 6.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.6 6.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.6 9.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.6 4.7 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
1.5 6.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
1.5 4.5 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.5 4.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.5 16.0 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
1.4 4.3 GO:2000096 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
1.4 4.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
1.4 7.1 GO:0035262 gonad morphogenesis(GO:0035262)
1.4 4.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.4 26.5 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
1.4 19.1 GO:0050901 leukocyte tethering or rolling(GO:0050901)
1.3 9.0 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
1.3 5.1 GO:0007412 axon target recognition(GO:0007412)
1.3 7.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.2 2.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.2 7.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.2 10.8 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
1.2 15.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.1 8.9 GO:0035881 amacrine cell differentiation(GO:0035881)
1.1 4.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.1 14.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
1.1 2.2 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
1.1 21.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
1.1 3.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
1.1 8.4 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
1.0 4.1 GO:2000427 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of apoptotic cell clearance(GO:2000425) positive regulation of apoptotic cell clearance(GO:2000427)
1.0 6.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
1.0 6.0 GO:1902950 regulation of dendritic spine maintenance(GO:1902950) positive regulation of dendritic spine maintenance(GO:1902952)
1.0 4.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.0 3.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.9 7.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.9 16.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.9 6.6 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.9 31.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.9 3.7 GO:0072697 protein localization to cell cortex(GO:0072697)
0.9 13.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.9 3.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.9 2.6 GO:0021699 cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.9 6.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.9 12.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.8 15.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.8 3.3 GO:0060017 parathyroid gland development(GO:0060017)
0.8 0.8 GO:0061324 cardiac right atrium morphogenesis(GO:0003213) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.8 2.4 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.8 8.1 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.8 4.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.8 3.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.8 12.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.8 3.2 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.8 17.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.8 12.8 GO:0050832 defense response to fungus(GO:0050832)
0.8 2.4 GO:0090285 regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.8 1.6 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.8 2.4 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.8 2.3 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.7 3.7 GO:0046880 progesterone secretion(GO:0042701) regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.7 7.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.7 11.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.7 1.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.7 5.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.7 11.9 GO:0021535 cell migration in hindbrain(GO:0021535)
0.7 2.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.7 28.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 2.7 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.7 6.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.7 4.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.7 7.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.7 3.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.6 12.7 GO:0010107 potassium ion import(GO:0010107)
0.6 2.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.6 2.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.6 3.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.6 8.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.6 3.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.6 5.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 4.2 GO:0072176 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.6 3.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.6 16.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.6 8.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.6 1.7 GO:0035973 aggrephagy(GO:0035973)
0.6 0.6 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.6 19.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.6 2.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.6 7.9 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.6 5.0 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.5 5.5 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.5 1.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.5 3.8 GO:0090091 microspike assembly(GO:0030035) regulation of microvillus assembly(GO:0032534) positive regulation of extracellular matrix disassembly(GO:0090091)
0.5 2.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.5 36.9 GO:0000045 autophagosome assembly(GO:0000045)
0.5 2.6 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.5 3.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.5 2.5 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.5 2.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.5 2.9 GO:1903056 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 3.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.5 2.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.5 2.3 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.5 0.9 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.5 3.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.5 3.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.5 12.9 GO:0060669 embryonic placenta morphogenesis(GO:0060669)
0.5 0.5 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.5 2.3 GO:0051013 microtubule severing(GO:0051013)
0.4 10.3 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.4 4.9 GO:0051764 actin crosslink formation(GO:0051764)
0.4 3.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.4 2.2 GO:0006527 arginine catabolic process(GO:0006527)
0.4 0.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 2.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.4 7.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 5.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.4 9.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.4 10.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.4 1.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 2.1 GO:0046208 spermine catabolic process(GO:0046208)
0.4 4.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.4 11.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.4 11.4 GO:0009299 mRNA transcription(GO:0009299)
0.4 2.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 1.2 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.4 2.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 24.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.4 5.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.4 0.4 GO:0007172 signal complex assembly(GO:0007172) negative regulation of synapse assembly(GO:0051964)
0.4 1.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.4 0.8 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.4 6.3 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601) regulation of glutamate receptor signaling pathway(GO:1900449)
0.4 2.7 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.4 6.9 GO:0071625 vocalization behavior(GO:0071625)
0.4 1.9 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.4 6.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.4 3.1 GO:0045760 positive regulation of action potential(GO:0045760)
0.4 8.0 GO:0060384 innervation(GO:0060384)
0.4 1.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.4 1.1 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.4 1.1 GO:0045109 intermediate filament organization(GO:0045109)
0.4 2.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 3.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 0.7 GO:0031133 regulation of axon diameter(GO:0031133)
0.4 10.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 1.8 GO:0003383 apical constriction(GO:0003383)
0.4 1.8 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 8.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.4 9.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.4 1.8 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 20.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 11.0 GO:0050919 negative chemotaxis(GO:0050919)
0.4 3.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.3 2.1 GO:0016198 axon choice point recognition(GO:0016198)
0.3 3.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.3 1.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.3 2.0 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.3 2.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 3.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 1.3 GO:0030220 platelet formation(GO:0030220)
0.3 1.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.3 2.9 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.3 1.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.3 5.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 3.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.3 3.2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.3 1.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 4.8 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.3 1.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 2.8 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 5.1 GO:0021591 ventricular system development(GO:0021591)
0.3 5.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 1.8 GO:0060346 bone trabecula formation(GO:0060346)
0.3 2.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.3 1.5 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.3 0.9 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.3 2.4 GO:0006265 DNA topological change(GO:0006265) embryonic cleavage(GO:0040016)
0.3 3.8 GO:0007340 acrosome reaction(GO:0007340)
0.3 17.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.3 0.9 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.3 2.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 2.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.3 1.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.3 9.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.3 20.9 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.3 8.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.3 1.1 GO:0048148 behavioral response to cocaine(GO:0048148)
0.3 2.0 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 1.9 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 1.7 GO:0006968 cellular defense response(GO:0006968)
0.3 2.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.3 7.8 GO:0016578 histone deubiquitination(GO:0016578)
0.3 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.8 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 1.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.3 2.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 3.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 9.4 GO:0007520 myoblast fusion(GO:0007520)
0.3 2.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.3 10.3 GO:0070527 platelet aggregation(GO:0070527)
0.3 1.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3 1.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 1.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 0.7 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 1.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 2.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.2 1.7 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 0.2 GO:0071864 positive regulation of cell proliferation in bone marrow(GO:0071864)
0.2 3.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 3.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 2.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 19.3 GO:0010506 regulation of autophagy(GO:0010506)
0.2 8.9 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.2 0.7 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 0.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 4.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 7.3 GO:0015844 monoamine transport(GO:0015844)
0.2 5.0 GO:0048512 circadian behavior(GO:0048512)
0.2 10.9 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.2 12.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.4 GO:0072553 terminal button organization(GO:0072553)
0.2 0.6 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.2 0.8 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.2 1.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 1.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 0.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 0.8 GO:1904587 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.2 1.0 GO:1903887 motile primary cilium assembly(GO:1903887)
0.2 1.4 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.2 2.9 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.2 0.6 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.2 0.4 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.2 0.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 1.3 GO:0051014 actin filament severing(GO:0051014)
0.2 1.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 7.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 2.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 32.6 GO:0007018 microtubule-based movement(GO:0007018)
0.2 0.8 GO:2001197 positive regulation of extracellular matrix assembly(GO:1901203) positive regulation of extracellular matrix organization(GO:1903055) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 1.0 GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.2 1.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 5.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 9.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.2 4.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.2 5.5 GO:0097202 activation of cysteine-type endopeptidase activity(GO:0097202)
0.2 1.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 2.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 3.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 1.0 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 2.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 3.3 GO:0031648 protein destabilization(GO:0031648)
0.1 0.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.6 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.1 2.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 9.2 GO:0006612 protein targeting to membrane(GO:0006612)
0.1 4.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 5.0 GO:0051591 response to cAMP(GO:0051591)
0.1 0.4 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.1 1.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.9 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.9 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 4.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.5 GO:0010288 response to lead ion(GO:0010288)
0.1 1.1 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 1.8 GO:0006308 DNA catabolic process(GO:0006308) DNA-templated transcription, termination(GO:0006353)
0.1 17.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.1 0.4 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.6 GO:0070828 heterochromatin organization(GO:0070828)
0.1 1.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.7 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 4.0 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 10.9 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.1 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 3.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.9 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.7 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 1.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 2.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 4.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 7.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 2.1 GO:0006301 postreplication repair(GO:0006301)
0.1 3.0 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 4.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.4 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.3 GO:0060479 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.1 GO:0008542 visual learning(GO:0008542)
0.1 1.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.3 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 6.5 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 2.3 GO:0018208 peptidyl-proline modification(GO:0018208)
0.1 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 4.4 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.1 0.9 GO:0001967 suckling behavior(GO:0001967)
0.1 1.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.3 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.3 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 3.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.3 GO:0030317 sperm motility(GO:0030317)
0.1 1.0 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 2.7 GO:0048167 regulation of synaptic plasticity(GO:0048167)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 3.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.7 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.2 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0001825 blastocyst formation(GO:0001825)
0.0 0.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 48.9 GO:0045298 tubulin complex(GO:0045298)
4.0 16.1 GO:0044307 dendritic branch(GO:0044307)
3.7 33.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
3.6 10.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
3.1 30.6 GO:0044327 dendritic spine head(GO:0044327)
3.0 17.9 GO:0097427 microtubule bundle(GO:0097427)
3.0 20.9 GO:0031933 telomeric heterochromatin(GO:0031933)
2.9 32.4 GO:0031258 lamellipodium membrane(GO:0031258)
2.8 16.9 GO:1990635 proximal dendrite(GO:1990635)
2.5 10.0 GO:1902737 dendritic filopodium(GO:1902737)
2.5 61.5 GO:0071565 nBAF complex(GO:0071565)
2.3 18.7 GO:0001520 outer dense fiber(GO:0001520)
2.3 15.8 GO:0071437 invadopodium(GO:0071437)
2.1 17.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
2.1 12.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.0 40.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.9 11.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.7 6.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
1.6 8.0 GO:0030314 junctional membrane complex(GO:0030314)
1.6 36.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
1.5 11.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.4 23.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
1.2 3.7 GO:0043512 inhibin A complex(GO:0043512)
1.1 9.7 GO:0070688 MLL5-L complex(GO:0070688)
1.1 3.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
1.1 2.1 GO:1990812 growth cone filopodium(GO:1990812)
1.0 6.8 GO:0005638 lamin filament(GO:0005638)
1.0 5.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.9 6.6 GO:0000322 storage vacuole(GO:0000322)
0.9 7.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.9 10.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.9 6.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.9 22.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 5.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.8 1.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.8 8.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.8 10.9 GO:0031528 microvillus membrane(GO:0031528)
0.8 7.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.7 14.9 GO:0042734 presynaptic membrane(GO:0042734)
0.7 13.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 2.0 GO:0032426 stereocilium tip(GO:0032426)
0.7 8.7 GO:0042788 polysomal ribosome(GO:0042788)
0.7 3.3 GO:0043083 synaptic cleft(GO:0043083)
0.6 37.9 GO:0034704 calcium channel complex(GO:0034704)
0.6 5.9 GO:0042599 lamellar body(GO:0042599)
0.6 1.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.6 27.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 4.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 9.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.5 23.6 GO:0031941 filamentous actin(GO:0031941)
0.5 6.1 GO:0000124 SAGA complex(GO:0000124)
0.5 6.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 21.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.5 22.5 GO:0044295 axonal growth cone(GO:0044295)
0.5 16.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 2.4 GO:0001651 dense fibrillar component(GO:0001651)
0.5 41.1 GO:0043198 dendritic shaft(GO:0043198)
0.5 4.2 GO:0005883 neurofilament(GO:0005883)
0.5 2.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 8.1 GO:0031430 M band(GO:0031430)
0.4 3.1 GO:0070578 RISC-loading complex(GO:0070578)
0.4 1.3 GO:0000235 astral microtubule(GO:0000235)
0.4 26.0 GO:0005871 kinesin complex(GO:0005871)
0.4 7.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 4.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 6.4 GO:0036038 MKS complex(GO:0036038)
0.4 1.6 GO:0036449 microtubule minus-end(GO:0036449)
0.4 22.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 22.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 4.8 GO:0005869 dynactin complex(GO:0005869)
0.3 7.1 GO:0005875 microtubule associated complex(GO:0005875)
0.3 9.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 1.3 GO:0097165 nuclear stress granule(GO:0097165)
0.3 8.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 14.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 17.1 GO:0005776 autophagosome(GO:0005776)
0.3 0.6 GO:0031094 platelet dense tubular network(GO:0031094)
0.3 89.8 GO:0005874 microtubule(GO:0005874)
0.3 1.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 2.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 1.9 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 2.7 GO:0070545 PeBoW complex(GO:0070545)
0.3 18.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 0.8 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3 2.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 3.1 GO:0042581 specific granule(GO:0042581)
0.3 5.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 11.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.2 4.1 GO:0001891 phagocytic cup(GO:0001891)
0.2 7.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 17.1 GO:0043204 perikaryon(GO:0043204)
0.2 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 8.5 GO:0008180 COP9 signalosome(GO:0008180)
0.2 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.5 GO:0097443 sorting endosome(GO:0097443)
0.2 0.9 GO:0001652 granular component(GO:0001652)
0.2 24.6 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 0.8 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 1.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 5.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 4.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 15.1 GO:0008021 synaptic vesicle(GO:0008021)
0.2 3.7 GO:0005685 U1 snRNP(GO:0005685)
0.2 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.3 GO:0002102 podosome(GO:0002102)
0.2 4.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.4 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 1.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.0 GO:0001650 fibrillar center(GO:0001650)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 5.4 GO:0000786 nucleosome(GO:0000786)
0.1 5.0 GO:0043596 nuclear replication fork(GO:0043596)
0.1 11.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 1.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 16.5 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.3 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 3.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 3.2 GO:1990391 DNA repair complex(GO:1990391)
0.1 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 7.2 GO:0001726 ruffle(GO:0001726)
0.1 5.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.7 GO:0051233 spindle midzone(GO:0051233)
0.1 3.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 2.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 9.4 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 3.7 GO:0005903 brush border(GO:0005903)
0.1 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.1 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.0 GO:0000502 proteasome complex(GO:0000502)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 3.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 8.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 41.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
4.9 14.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
4.4 17.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
4.0 12.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
3.8 11.5 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
3.7 18.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
3.4 23.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
3.4 10.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
3.0 9.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
2.9 17.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.8 14.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.7 65.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.7 8.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
2.6 10.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
2.5 15.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
2.5 12.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.5 54.1 GO:0034185 apolipoprotein binding(GO:0034185)
2.4 7.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
2.3 11.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
2.2 6.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
2.2 11.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
2.2 10.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
2.1 4.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
2.0 8.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
2.0 18.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.9 14.9 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
1.8 11.1 GO:0032051 clathrin light chain binding(GO:0032051)
1.8 52.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.7 14.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
1.7 1.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.7 18.7 GO:0004017 adenylate kinase activity(GO:0004017)
1.6 9.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.6 11.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.6 6.3 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
1.6 7.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.6 4.7 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.5 3.1 GO:0097016 L27 domain binding(GO:0097016)
1.5 11.9 GO:0051434 BH3 domain binding(GO:0051434)
1.4 18.6 GO:0005522 profilin binding(GO:0005522)
1.4 4.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
1.4 9.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.4 9.5 GO:0070087 DNA translocase activity(GO:0015616) chromo shadow domain binding(GO:0070087)
1.3 14.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.3 14.2 GO:0030957 Tat protein binding(GO:0030957)
1.3 28.2 GO:0001784 phosphotyrosine binding(GO:0001784)
1.3 12.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.3 5.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.2 16.1 GO:0031005 filamin binding(GO:0031005)
1.2 8.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
1.2 7.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.2 3.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
1.1 4.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1 7.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.1 3.3 GO:0051011 microtubule minus-end binding(GO:0051011)
1.1 3.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.1 53.0 GO:0045499 chemorepellent activity(GO:0045499)
1.1 23.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.0 20.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.0 8.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.0 7.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.0 33.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.0 4.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.0 11.7 GO:0005057 receptor signaling protein activity(GO:0005057)
1.0 13.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.9 3.6 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.9 8.8 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.9 12.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.9 9.4 GO:0003680 AT DNA binding(GO:0003680)
0.8 10.0 GO:0070097 delta-catenin binding(GO:0070097)
0.8 3.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.8 2.5 GO:0008527 taste receptor activity(GO:0008527)
0.8 2.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.8 13.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.8 8.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.8 9.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.8 2.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.8 2.4 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.8 17.5 GO:0005521 lamin binding(GO:0005521)
0.8 11.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.8 27.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 4.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.7 2.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.7 2.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.7 25.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.7 2.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.7 5.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.7 8.9 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.7 2.7 GO:0005165 neurotrophin receptor binding(GO:0005165)
0.7 2.7 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.7 2.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.7 14.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.7 7.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.6 9.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 3.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 14.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.6 28.8 GO:0070888 E-box binding(GO:0070888)
0.6 9.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.6 1.9 GO:0030350 iron-responsive element binding(GO:0030350)
0.6 1.8 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.6 3.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.6 3.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.6 2.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 4.5 GO:0050693 LBD domain binding(GO:0050693)
0.5 9.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 2.2 GO:0043426 MRF binding(GO:0043426)
0.5 0.5 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.5 4.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 32.5 GO:0003777 microtubule motor activity(GO:0003777)
0.5 10.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 4.7 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.5 2.1 GO:0003883 CTP synthase activity(GO:0003883)
0.5 5.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.5 5.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.5 7.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.5 2.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.5 2.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 14.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.5 1.9 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.5 12.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.5 27.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.5 2.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 2.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.4 7.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 4.0 GO:0030274 LIM domain binding(GO:0030274)
0.4 19.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.4 1.3 GO:0070051 fibrinogen binding(GO:0070051)
0.4 11.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 7.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.4 5.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 6.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.4 1.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 9.6 GO:0003785 actin monomer binding(GO:0003785)
0.4 2.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.4 5.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 1.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 7.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 24.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 1.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4 5.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.4 2.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 3.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 62.1 GO:0008017 microtubule binding(GO:0008017)
0.4 6.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.4 1.8 GO:0032767 copper-dependent protein binding(GO:0032767)
0.4 2.5 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.4 18.9 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.4 6.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.4 7.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 5.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 9.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 11.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 1.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 2.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.3 21.0 GO:0002039 p53 binding(GO:0002039)
0.3 4.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 3.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 12.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 2.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 9.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 6.5 GO:0003924 GTPase activity(GO:0003924)
0.3 9.3 GO:0017091 AU-rich element binding(GO:0017091)
0.3 0.8 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3 4.4 GO:0070064 proline-rich region binding(GO:0070064)
0.3 9.7 GO:0030332 cyclin binding(GO:0030332)
0.3 2.6 GO:0031996 thioesterase binding(GO:0031996)
0.3 1.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 1.0 GO:0070878 primary miRNA binding(GO:0070878)
0.2 5.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.0 GO:0070513 death domain binding(GO:0070513)
0.2 1.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.2 7.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 5.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 12.5 GO:0019003 GDP binding(GO:0019003)
0.2 10.0 GO:0017022 myosin binding(GO:0017022)
0.2 0.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.2 5.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 2.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 25.7 GO:0017124 SH3 domain binding(GO:0017124)
0.2 8.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 1.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 6.7 GO:0097110 scaffold protein binding(GO:0097110)
0.2 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.2 0.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 4.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 17.8 GO:0043130 ubiquitin binding(GO:0043130)
0.2 3.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 74.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 3.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 4.4 GO:0045296 cadherin binding(GO:0045296)
0.2 2.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 2.0 GO:0042805 actinin binding(GO:0042805)
0.1 2.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 9.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 3.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 4.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 15.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.3 GO:0030552 cAMP binding(GO:0030552)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 81.2 GO:0008270 zinc ion binding(GO:0008270)
0.1 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.3 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 3.3 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) NADPH:sulfur oxidoreductase activity(GO:0043914) epoxyqueuosine reductase activity(GO:0052693)
0.1 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 5.2 GO:0030674 protein binding, bridging(GO:0030674)
0.1 5.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.4 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.1 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 17.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.7 GO:0001848 complement binding(GO:0001848)
0.1 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 21.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 63.9 GO:0044822 poly(A) RNA binding(GO:0044822)
0.1 14.3 GO:0005525 GTP binding(GO:0005525)
0.1 1.9 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 1.7 GO:0008009 chemokine activity(GO:0008009)
0.1 4.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) axon guidance receptor activity(GO:0008046)
0.0 2.9 GO:0042277 peptide binding(GO:0042277)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 2.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)