Motif ID: Sox30

Z-value: 0.502


Transcription factors associated with Sox30:

Gene SymbolEntrez IDGene Name
Sox30 ENSMUSG00000040489.5 Sox30



Activity profile for motif Sox30.

activity profile for motif Sox30


Sorted Z-values histogram for motif Sox30

Sorted Z-values for motif Sox30



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 9.296 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr10_+_17796256 3.861 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr14_+_116925379 3.120 ENSMUST00000088483.3
 Gpc6
glypican 6
chrX_-_134161928 3.114 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr1_+_135729147 2.861 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr9_+_7764041 2.826 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr3_+_34649987 2.647 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr10_-_24836165 2.519 ENSMUST00000020169.7
 Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr13_-_102958084 2.511 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chr5_+_92809372 2.280 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr2_-_101883010 2.061 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr9_-_32541589 2.037 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr18_-_88927447 1.950 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr2_-_58052832 1.948 ENSMUST00000090940.5
 Ermn
ermin, ERM-like protein
chr12_-_99883429 1.564 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr8_+_46490968 1.538 ENSMUST00000110372.1
ENSMUST00000130563.1
 Acsl1

acyl-CoA synthetase long-chain family member 1

chr6_-_12749193 1.302 ENSMUST00000046121.6
ENSMUST00000172356.1
 Thsd7a

thrombospondin, type I, domain containing 7A

chr10_-_53647080 1.276 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr11_+_3983704 1.254 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_3983636 1.216 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr7_+_90426312 1.201 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89
chr6_-_3494587 1.158 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr2_+_3114220 1.155 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr3_-_8964037 1.130 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr18_-_62756275 1.107 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr14_-_19823807 1.064 ENSMUST00000022341.5
 2700060E02Rik
RIKEN cDNA 2700060E02 gene
chr5_-_62765618 1.061 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_72111651 1.044 ENSMUST00000185117.1
 Tcf12
transcription factor 12
chr19_+_44293676 1.023 ENSMUST00000026221.5
 Scd2
stearoyl-Coenzyme A desaturase 2
chr9_-_103480328 1.008 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr10_+_90829538 0.921 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_106715251 0.883 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
 Pecam1



platelet/endothelial cell adhesion molecule 1



chr10_+_90829409 0.775 ENSMUST00000182202.1
ENSMUST00000182966.1
 Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr2_-_119787504 0.765 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
 Rpap1


RNA polymerase II associated protein 1


chr4_-_119190005 0.722 ENSMUST00000138395.1
ENSMUST00000156746.1
 Ermap

erythroblast membrane-associated protein

chr10_-_62792243 0.706 ENSMUST00000020268.5
 Ccar1
cell division cycle and apoptosis regulator 1
chr3_+_19957037 0.580 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
 Cp


ceruloplasmin


chrX_+_56786527 0.459 ENSMUST00000144600.1
 Fhl1
four and a half LIM domains 1
chr13_-_97747373 0.454 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_134396320 0.447 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2
chr7_+_127800604 0.383 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr4_+_137993445 0.376 ENSMUST00000105831.2
ENSMUST00000084214.5
 Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr19_-_24477356 0.353 ENSMUST00000099556.1
 Fam122a
family with sequence similarity 122, member A
chr5_-_137072254 0.327 ENSMUST00000077523.3
ENSMUST00000041388.4
 Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr13_-_56135629 0.299 ENSMUST00000016081.6
ENSMUST00000045788.7
 H2afy

H2A histone family, member Y

chr4_+_109343029 0.255 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chr6_-_122340200 0.230 ENSMUST00000159384.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr1_+_37997975 0.193 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr6_-_132314757 0.177 ENSMUST00000048686.8
 Prpmp5
proline-rich protein MP5
chr12_+_8674224 0.168 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr12_+_8674129 0.127 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr15_+_100038635 0.102 ENSMUST00000100203.3
 Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr1_+_10056922 0.066 ENSMUST00000149214.1
 Cspp1
centrosome and spindle pole associated protein 1
chr10_+_14523062 0.060 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr11_+_51261719 0.031 ENSMUST00000130641.1
 Clk4
CDC like kinase 4
chr14_-_68655804 0.026 ENSMUST00000111072.1
ENSMUST00000022642.5
 Adam28

a disintegrin and metallopeptidase domain 28


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 9.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 2.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 2.1 GO:0038203 TORC2 signaling(GO:0038203)
0.4 2.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 1.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.9 GO:0050904 diapedesis(GO:0050904)
0.2 2.5 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 2.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.5 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.3 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 2.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.3 GO:0033128 negative regulation of histone phosphorylation(GO:0033128) positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.3 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 1.0 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.3 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 2.9 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.6 GO:0046688 response to copper ion(GO:0046688)
0.0 2.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 2.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 1.2 GO:0051297 centrosome organization(GO:0051297)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0033269 internode region of axon(GO:0033269)
0.2 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 2.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 3.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 2.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.9 GO:0043296 apical junction complex(GO:0043296)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.6 2.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.5 1.5 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.3 1.0 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 2.6 GO:0035198 miRNA binding(GO:0035198)
0.1 3.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 9.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)