Motif ID: Spib
Z-value: 1.195
Transcription factors associated with Spib:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Spib | ENSMUSG00000008193.7 | Spib |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 103 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 26.0 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 5.5 | 16.5 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 0.1 | 10.2 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 1.5 | 8.8 | GO:0032796 | uropod organization(GO:0032796) |
| 2.0 | 7.8 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
| 1.5 | 7.4 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 1.4 | 6.9 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
| 1.7 | 6.7 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.1 | 6.6 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.2 | 6.0 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 5.6 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.1 | 5.1 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
| 1.6 | 4.8 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) |
| 0.2 | 4.7 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 3.9 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 1.3 | 3.8 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.9 | 3.8 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
| 0.5 | 3.8 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.7 | 3.7 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 3.7 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 58 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 27.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.3 | 25.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 20.2 | GO:0005768 | endosome(GO:0005768) |
| 0.0 | 14.2 | GO:0030054 | cell junction(GO:0030054) |
| 0.1 | 11.0 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.4 | 10.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 10.2 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 9.5 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.2 | 7.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 6.9 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 6.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.5 | 5.1 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 5.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 1.0 | 4.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.0 | 4.0 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 3.9 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 3.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 3.8 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.5 | 3.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.8 | 3.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 78 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 16.5 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.1 | 11.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 2.7 | 10.8 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.9 | 8.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.1 | 7.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 7.3 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 6.8 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 6.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 5.5 | GO:0019209 | kinase activator activity(GO:0019209) |
| 0.6 | 5.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.4 | 4.9 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.8 | 4.8 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.4 | 4.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.3 | 4.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 4.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.4 | 4.1 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.4 | 4.0 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 4.0 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 3.8 | 3.8 | GO:0019864 | IgG binding(GO:0019864) |
| 0.3 | 3.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
