Motif ID: Spic
Z-value: 1.038
Transcription factors associated with Spic:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Spic | ENSMUSG00000004359.10 | Spic |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Spic | mm10_v2_chr10_-_88683021_88683025 | -0.04 | 7.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.9 | 11.8 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
1.9 | 9.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
1.3 | 9.0 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
1.3 | 7.6 | GO:0032796 | uropod organization(GO:0032796) |
1.2 | 5.8 | GO:0015671 | oxygen transport(GO:0015671) |
1.0 | 3.1 | GO:0016068 | regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068) |
0.9 | 2.6 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) |
0.9 | 3.5 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.8 | 3.4 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) |
0.8 | 2.5 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.8 | 2.4 | GO:2000562 | negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
0.8 | 2.4 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.7 | 3.0 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.7 | 0.7 | GO:1900426 | positive regulation of defense response to bacterium(GO:1900426) |
0.7 | 2.1 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.7 | 2.0 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.7 | 2.0 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
0.7 | 2.0 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
0.7 | 2.0 | GO:0045410 | positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
0.6 | 1.9 | GO:2001180 | negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180) |
0.6 | 2.3 | GO:0050904 | diapedesis(GO:0050904) |
0.5 | 2.1 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
0.5 | 1.0 | GO:1900673 | olefin metabolic process(GO:1900673) |
0.4 | 7.0 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.4 | 1.3 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.4 | 2.5 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.4 | 0.8 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
0.4 | 1.2 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.4 | 6.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.4 | 3.3 | GO:0071569 | protein ufmylation(GO:0071569) |
0.4 | 1.1 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.3 | 2.4 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.3 | 1.0 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.3 | 0.6 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.3 | 1.5 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.3 | 4.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.3 | 2.2 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.3 | 0.8 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
0.3 | 3.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.3 | 0.8 | GO:1903054 | lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334) |
0.2 | 4.7 | GO:0019835 | cytolysis(GO:0019835) |
0.2 | 0.7 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.2 | 0.9 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.2 | 0.7 | GO:0000087 | mitotic M phase(GO:0000087) |
0.2 | 1.3 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
0.2 | 1.5 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.2 | 0.6 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.2 | 1.1 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.2 | 2.0 | GO:1990173 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.2 | 0.7 | GO:0006788 | heme oxidation(GO:0006788) |
0.2 | 0.5 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.2 | 0.6 | GO:0003430 | tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430) |
0.2 | 0.8 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
0.2 | 0.5 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
0.2 | 2.4 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
0.1 | 0.7 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
0.1 | 0.6 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.1 | 0.7 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.1 | 0.4 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
0.1 | 0.3 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.1 | 0.6 | GO:0018343 | protein farnesylation(GO:0018343) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.1 | 0.4 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.1 | 0.5 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.1 | 1.1 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.1 | 0.4 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
0.1 | 1.1 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 0.7 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
0.1 | 1.8 | GO:0050832 | defense response to fungus(GO:0050832) |
0.1 | 0.5 | GO:0046469 | platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469) |
0.1 | 0.9 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.1 | 1.7 | GO:0045954 | positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
0.1 | 1.0 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
0.1 | 0.5 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.1 | 0.8 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.1 | 1.2 | GO:0015816 | glycine transport(GO:0015816) |
0.1 | 0.5 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.1 | 1.4 | GO:0003214 | cardiac left ventricle morphogenesis(GO:0003214) lung-associated mesenchyme development(GO:0060484) |
0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.1 | 1.0 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.1 | 0.9 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.1 | 0.3 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
0.1 | 0.5 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.1 | 0.6 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
0.1 | 0.2 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 0.4 | GO:0007000 | nucleolus organization(GO:0007000) |
0.1 | 0.5 | GO:0051014 | actin filament severing(GO:0051014) |
0.1 | 0.2 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
0.1 | 0.2 | GO:0032493 | response to bacterial lipoprotein(GO:0032493) |
0.1 | 0.9 | GO:0035635 | entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535) |
0.1 | 1.1 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
0.1 | 0.5 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) |
0.1 | 0.6 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.1 | 0.2 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 1.0 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 1.4 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.1 | 1.3 | GO:0007035 | vacuolar acidification(GO:0007035) |
0.1 | 1.1 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.1 | 0.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.1 | 0.5 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
0.1 | 0.9 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 0.6 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.1 | 0.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 0.3 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.1 | 0.1 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.1 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.1 | 0.5 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.1 | 0.6 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.1 | 0.2 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.1 | 0.4 | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) |
0.1 | 1.1 | GO:0045116 | protein neddylation(GO:0045116) |
0.1 | 3.2 | GO:0042255 | ribosome assembly(GO:0042255) |
0.1 | 0.2 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
0.1 | 0.3 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.1 | 0.8 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.1 | 1.4 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 1.0 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
0.0 | 3.8 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.0 | 0.6 | GO:0010388 | cullin deneddylation(GO:0010388) |
0.0 | 2.5 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.9 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 1.8 | GO:0047496 | vesicle transport along microtubule(GO:0047496) |
0.0 | 1.5 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 0.7 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.1 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
0.0 | 0.4 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.0 | 1.5 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 1.0 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
0.0 | 3.9 | GO:0006909 | phagocytosis(GO:0006909) |
0.0 | 0.5 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
0.0 | 1.0 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
0.0 | 0.2 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.1 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
0.0 | 0.9 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 1.0 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
0.0 | 1.8 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.0 | 0.4 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
0.0 | 1.4 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.8 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.6 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.2 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.0 | 0.5 | GO:0006298 | mismatch repair(GO:0006298) |
0.0 | 1.2 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
0.0 | 0.1 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.2 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
0.0 | 1.3 | GO:0035904 | aorta development(GO:0035904) |
0.0 | 0.8 | GO:0001706 | endoderm formation(GO:0001706) |
0.0 | 0.4 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.5 | GO:0002237 | response to molecule of bacterial origin(GO:0002237) response to lipopolysaccharide(GO:0032496) |
0.0 | 0.5 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.3 | GO:0017144 | drug metabolic process(GO:0017144) |
0.0 | 0.6 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.4 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
0.0 | 0.1 | GO:0071105 | response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675) |
0.0 | 0.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
0.0 | 1.5 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 0.1 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.0 | 0.4 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.1 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.5 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
0.0 | 0.7 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.8 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
0.0 | 0.8 | GO:0030838 | positive regulation of actin filament polymerization(GO:0030838) |
0.0 | 1.2 | GO:1903749 | positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 0.1 | GO:0000103 | sulfate assimilation(GO:0000103) |
0.0 | 0.9 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.1 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
0.0 | 0.1 | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
0.0 | 1.6 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 0.3 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 0.2 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
0.0 | 0.4 | GO:0043039 | tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039) |
0.0 | 0.5 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.8 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.7 | 5.8 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.6 | 2.4 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.6 | 2.2 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
0.5 | 2.3 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.4 | 2.0 | GO:1990745 | EARP complex(GO:1990745) |
0.3 | 1.0 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.3 | 3.1 | GO:0030008 | TRAPP complex(GO:0030008) |
0.3 | 2.2 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.3 | 7.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.3 | 1.1 | GO:0032127 | dense core granule membrane(GO:0032127) |
0.3 | 0.8 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.3 | 3.8 | GO:0042555 | MCM complex(GO:0042555) |
0.2 | 1.0 | GO:0044307 | dendritic branch(GO:0044307) |
0.2 | 15.3 | GO:0005581 | collagen trimer(GO:0005581) |
0.2 | 2.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.2 | 0.6 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.2 | 2.0 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.2 | 1.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.2 | 1.8 | GO:0071439 | clathrin complex(GO:0071439) |
0.2 | 1.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.2 | 5.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.2 | 1.0 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.1 | 1.0 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.1 | 0.7 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 0.7 | GO:0097441 | basilar dendrite(GO:0097441) |
0.1 | 2.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.1 | 0.5 | GO:0097651 | phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
0.1 | 0.8 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 1.5 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.4 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.1 | 5.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.1 | 1.0 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 0.3 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.1 | 0.4 | GO:0032021 | NELF complex(GO:0032021) |
0.1 | 1.3 | GO:0005869 | dynactin complex(GO:0005869) |
0.1 | 0.9 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.1 | 0.9 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 2.1 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.1 | 0.6 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.1 | 0.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 0.1 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.1 | 0.9 | GO:0032584 | growth cone membrane(GO:0032584) |
0.1 | 0.5 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 0.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 5.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 0.4 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 2.4 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 15.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.1 | 0.8 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.1 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 0.9 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.1 | 0.7 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 10.3 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.1 | 0.8 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.1 | 1.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 1.3 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.0 | 0.5 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.6 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 2.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 8.0 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 2.0 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 1.3 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 3.6 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 1.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 3.0 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 1.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 2.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.6 | GO:0032040 | small-subunit processome(GO:0032040) |
0.0 | 0.3 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.2 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.5 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.2 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.4 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.1 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.0 | 0.5 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 0.8 | GO:0005840 | ribosome(GO:0005840) |
0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.8 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.8 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 2.1 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 0.1 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 1.4 | GO:0005794 | Golgi apparatus(GO:0005794) |
0.0 | 1.5 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.5 | GO:0005795 | Golgi stack(GO:0005795) |
0.0 | 0.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 3.1 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 0.4 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 12.9 | GO:0005829 | cytosol(GO:0005829) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 14.9 | GO:0019864 | IgG binding(GO:0019864) |
1.4 | 9.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
1.2 | 5.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
1.1 | 4.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.8 | 0.8 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.8 | 3.9 | GO:0045503 | dynein light chain binding(GO:0045503) |
0.8 | 7.6 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.5 | 3.7 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.5 | 1.5 | GO:0005118 | sevenless binding(GO:0005118) |
0.5 | 0.5 | GO:0001179 | RNA polymerase I transcription factor binding(GO:0001179) |
0.5 | 2.4 | GO:0051425 | PTB domain binding(GO:0051425) |
0.4 | 3.6 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.4 | 2.6 | GO:1901567 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
0.4 | 1.3 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.3 | 1.0 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.3 | 1.0 | GO:0034952 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity(GO:0008694) 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity(GO:0018791) bis(4-chlorophenyl)acetate decarboxylase activity(GO:0018792) 3,5-dibromo-4-hydroxybenzoate decarboxylase activity(GO:0018793) 2-hydroxyisobutyrate decarboxylase activity(GO:0018794) 2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity(GO:0018795) 2-hydroxyisophthalate decarboxylase activity(GO:0034524) dimethylmalonate decarboxylase activity(GO:0034782) 2,4,4-trimethyl-3-oxopentanoate decarboxylase activity(GO:0034853) 4,4-dimethyl-3-oxopentanoate decarboxylase activity(GO:0034854) 2,3,6-trihydroxyisonicotinate decarboxylase activity(GO:0034879) phenanthrene-4,5-dicarboxylate decarboxylase activity(GO:0034923) pyrrole-2-carboxylate decarboxylase activity(GO:0034941) terephthalate decarboxylase activity(GO:0034947) malonate semialdehyde decarboxylase activity(GO:0034952) 5-amino-4-imidazole carboxylate lyase activity(GO:0043727) 2-keto-4-methylthiobutyrate aminotransferase activity(GO:0043728) 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity(GO:0051997) |
0.3 | 0.6 | GO:0046921 | alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
0.3 | 1.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.3 | 1.8 | GO:0016936 | galactoside binding(GO:0016936) |
0.3 | 0.9 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
0.3 | 1.4 | GO:0070051 | fibrinogen binding(GO:0070051) |
0.3 | 2.0 | GO:0031432 | titin binding(GO:0031432) |
0.3 | 2.5 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.2 | 1.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.2 | 0.7 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) |
0.2 | 2.9 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.2 | 1.0 | GO:0018121 | imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102) |
0.2 | 2.2 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
0.2 | 1.8 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.2 | 4.4 | GO:0001968 | fibronectin binding(GO:0001968) |
0.2 | 0.6 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.2 | 0.5 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.2 | 0.9 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.2 | 0.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.2 | 0.7 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.2 | 0.5 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.2 | 0.5 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.2 | 2.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.2 | 0.5 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
0.2 | 0.6 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.2 | 0.8 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
0.1 | 0.6 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
0.1 | 1.0 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.1 | 2.8 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 0.9 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.1 | 2.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.1 | 1.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.1 | 0.8 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
0.1 | 1.5 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 1.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 1.0 | GO:0052872 | 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014) |
0.1 | 0.6 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.1 | 1.1 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.1 | 0.5 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
0.1 | 2.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.1 | 0.5 | GO:0071253 | connexin binding(GO:0071253) |
0.1 | 0.7 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.1 | 0.4 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.1 | 3.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 4.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.1 | 3.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 0.3 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.1 | 0.5 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
0.1 | 0.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.1 | 0.9 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
0.1 | 1.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 0.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.1 | 2.1 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.1 | 1.1 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 1.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.1 | 1.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.3 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.1 | 1.0 | GO:0016595 | glutamate binding(GO:0016595) |
0.1 | 2.0 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 0.8 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.9 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
0.1 | 1.1 | GO:0042287 | MHC protein binding(GO:0042287) |
0.1 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 1.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 1.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.0 | 1.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 1.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 2.7 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 1.8 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 1.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 1.0 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.1 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618) |
0.0 | 2.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.3 | GO:0034711 | inhibin binding(GO:0034711) |
0.0 | 7.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.2 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.0 | 1.5 | GO:0045296 | cadherin binding(GO:0045296) |
0.0 | 0.5 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 3.1 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 3.1 | GO:0019905 | syntaxin binding(GO:0019905) |
0.0 | 2.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.4 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.1 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.0 | 2.2 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 1.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.1 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 1.4 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
0.0 | 1.0 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.5 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 0.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.9 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.0 | 0.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.0 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.0 | 2.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 1.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 3.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.1 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.0 | 0.7 | GO:0035591 | signaling adaptor activity(GO:0035591) |
0.0 | 0.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 0.1 | GO:0050811 | GABA receptor binding(GO:0050811) |