Motif ID: Spic

Z-value: 1.038


Transcription factors associated with Spic:

Gene SymbolEntrez IDGene Name
Spic ENSMUSG00000004359.10 Spic

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spicmm10_v2_chr10_-_88683021_88683025-0.047.8e-01Click!


Activity profile for motif Spic.

activity profile for motif Spic


Sorted Z-values histogram for motif Spic

Sorted Z-values for motif Spic



Network of associatons between targets according to the STRING database.



First level regulatory network of Spic

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_136892867 8.048 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr4_-_136886187 7.029 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr1_-_171234290 6.910 ENSMUST00000079957.6
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr4_+_130913264 6.236 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr4_+_130913120 6.101 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr11_+_32276400 5.769 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr3_+_95526777 4.807 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr1_-_56978534 4.406 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr12_+_112760652 4.354 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr6_-_136941694 4.125 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr6_+_5725639 3.921 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr10_-_117282262 3.797 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr1_-_170976112 3.132 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fcgr2b


Fc receptor, IgG, low affinity IIb


chr15_-_66812593 3.085 ENSMUST00000100572.3
Sla
src-like adaptor
chr19_-_11604828 3.077 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr19_+_53529100 2.950 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr6_-_136941887 2.801 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr1_-_171059390 2.740 ENSMUST00000164044.1
ENSMUST00000169017.1
Fcgr3

Fc receptor, IgG, low affinity III

chr6_-_136941494 2.721 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr19_+_12460749 2.706 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr7_-_126704736 2.696 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr5_+_149265035 2.636 ENSMUST00000130144.1
ENSMUST00000071130.3
Alox5ap

arachidonate 5-lipoxygenase activating protein

chr17_+_29360923 2.608 ENSMUST00000024810.6
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr7_+_28440927 2.524 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr7_-_126704179 2.521 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr7_-_100964371 2.508 ENSMUST00000060174.4
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_-_106790143 2.435 ENSMUST00000038845.8
Cd53
CD53 antigen
chr7_-_126704522 2.408 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr1_+_87620334 2.399 ENSMUST00000042275.8
ENSMUST00000168783.1
Inpp5d

inositol polyphosphate-5-phosphatase D

chr16_+_36934976 2.365 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr11_-_106715251 2.283 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr1_+_74375203 2.218 ENSMUST00000027368.5
Slc11a1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr8_+_107056870 2.170 ENSMUST00000034392.5
ENSMUST00000170962.1
Nip7

nuclear import 7 homolog (S. cerevisiae)

chr3_-_96293953 2.129 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr6_+_137410721 2.117 ENSMUST00000167002.1
Ptpro
protein tyrosine phosphatase, receptor type, O
chr15_+_103453782 2.096 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr2_+_120463566 2.050 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr1_+_74771886 1.961 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chr2_-_129371131 1.950 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr1_+_171840607 1.946 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr5_+_122391878 1.908 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr6_+_123229843 1.845 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
Clec4n


C-type lectin domain family 4, member n


chr5_-_138171216 1.838 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_+_57279094 1.805 ENSMUST00000169220.2
ENSMUST00000005889.9
ENSMUST00000112870.4
Vav1


vav 1 oncogene


chr1_+_152807877 1.790 ENSMUST00000027754.6
Ncf2
neutrophil cytosolic factor 2
chr2_+_36230426 1.786 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr6_+_48684570 1.755 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
Gimap4




GTPase, IMAP family member 4




chr7_+_126695942 1.707 ENSMUST00000106369.1
Bola2
bolA-like 2 (E. coli)
chr5_-_134229581 1.689 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
Ncf1


neutrophil cytosolic factor 1


chr10_-_61383523 1.686 ENSMUST00000020289.8
Pald1
phosphatase domain containing, paladin 1
chr17_-_35916323 1.637 ENSMUST00000172642.1
ENSMUST00000174807.1
ENSMUST00000174349.1
ENSMUST00000025305.9
ENSMUST00000113782.3
Mrps18b




mitochondrial ribosomal protein S18B




chr19_-_41896132 1.589 ENSMUST00000038677.3
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr3_+_95499273 1.573 ENSMUST00000015664.3
Ctsk
cathepsin K
chr14_+_80000292 1.541 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr11_+_114851142 1.537 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr4_-_133874682 1.508 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr8_+_117498272 1.506 ENSMUST00000081232.7
Plcg2
phospholipase C, gamma 2
chr6_-_48708206 1.468 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr4_-_118489755 1.401 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr9_+_63602650 1.397 ENSMUST00000041551.7
Aagab
alpha- and gamma-adaptin binding protein
chr14_+_58070547 1.374 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr11_-_102469839 1.369 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr11_-_78984831 1.334 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr12_+_28751798 1.298 ENSMUST00000035657.7
Tssc1
tumor suppressing subtransferable candidate 1
chr7_+_122133036 1.296 ENSMUST00000033156.4
Dctn5
dynactin 5
chrX_-_8175890 1.295 ENSMUST00000143984.1
Tbc1d25
TBC1 domain family, member 25
chr3_-_106167564 1.253 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr8_-_70897407 1.253 ENSMUST00000054220.8
Rpl18a
ribosomal protein L18A
chr19_-_6084873 1.246 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr8_+_125730005 1.244 ENSMUST00000143504.1
Ntpcr
nucleoside-triphosphatase, cancer-related
chr7_+_28982832 1.240 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr15_-_31601786 1.238 ENSMUST00000022842.8
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr13_-_53473074 1.236 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr5_-_138171248 1.233 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_-_80264276 1.198 ENSMUST00000052499.7
Rps19bp1
ribosomal protein S19 binding protein 1
chrX_+_8271133 1.196 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr8_-_85080679 1.191 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83
chr3_-_59262825 1.177 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_-_138170992 1.157 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_-_33955658 1.143 ENSMUST00000174609.2
ENSMUST00000008812.7
Rps18

ribosomal protein S18

chr4_-_86857365 1.141 ENSMUST00000102814.4
Rps6
ribosomal protein S6
chr8_+_84701430 1.135 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr5_-_137502402 1.094 ENSMUST00000111035.1
ENSMUST00000031728.4
Pop7

processing of precursor 7, ribonuclease P family, (S. cerevisiae)

chr8_+_66386292 1.091 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr7_+_126695355 1.085 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr5_-_116024452 1.082 ENSMUST00000031486.7
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr11_-_78984946 1.080 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr14_-_55671873 1.074 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr17_+_33955902 1.069 ENSMUST00000173196.2
Vps52
vacuolar protein sorting 52 (yeast)
chr6_-_99028874 1.064 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr11_+_69323963 1.054 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr2_-_148045891 1.052 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr14_-_65593079 1.041 ENSMUST00000022609.5
Elp3
elongator acetyltransferase complex subunit 3
chr3_+_24333046 1.040 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr7_-_45124355 1.040 ENSMUST00000003521.8
Rps11
ribosomal protein S11
chr11_+_69324069 1.036 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr19_+_4231899 1.023 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr10_+_80292453 1.020 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr19_-_6084679 1.017 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr11_-_115133981 1.015 ENSMUST00000106561.1
ENSMUST00000051264.7
ENSMUST00000106562.2
Cd300lf


CD300 antigen like family member F


chr8_-_73353477 1.013 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr12_-_80643799 1.012 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr12_-_4592927 1.006 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr1_+_72711259 0.998 ENSMUST00000059980.9
Rpl37a
ribosomal protein L37a
chr11_+_49609263 0.997 ENSMUST00000020617.2
Flt4
FMS-like tyrosine kinase 4
chr2_-_25319095 0.986 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr17_+_50509518 0.977 ENSMUST00000043938.6
Plcl2
phospholipase C-like 2
chr19_-_45591820 0.972 ENSMUST00000160003.1
ENSMUST00000162879.1
Fbxw4

F-box and WD-40 domain protein 4

chr8_+_110618577 0.968 ENSMUST00000034190.9
Vac14
Vac14 homolog (S. cerevisiae)
chr9_+_64235201 0.967 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr11_+_69324055 0.964 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr17_+_33955812 0.955 ENSMUST00000025178.9
ENSMUST00000114330.2
Vps52

vacuolar protein sorting 52 (yeast)

chr4_+_44012661 0.951 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr11_-_97782409 0.951 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr9_-_119977250 0.945 ENSMUST00000035101.7
Csrnp1
cysteine-serine-rich nuclear protein 1
chr2_-_181459364 0.943 ENSMUST00000155535.1
ENSMUST00000029106.6
ENSMUST00000087409.3
Zbtb46


zinc finger and BTB domain containing 46


chr11_-_96916448 0.937 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr7_-_90129339 0.935 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr11_-_96916407 0.931 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr19_+_6941861 0.922 ENSMUST00000025910.5
Bad
BCL2-associated agonist of cell death
chr17_+_34604262 0.920 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr11_-_97782377 0.912 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr4_+_129335593 0.907 ENSMUST00000141235.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr11_-_103028204 0.904 ENSMUST00000155490.1
Dcakd
dephospho-CoA kinase domain containing
chr4_-_117891994 0.903 ENSMUST00000030265.3
Dph2
DPH2 homolog (S. cerevisiae)
chr15_-_78305603 0.902 ENSMUST00000096356.3
Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chrX_+_107255878 0.892 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr19_-_6084941 0.891 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1

zinc finger like protein 1

chr6_-_128437653 0.889 ENSMUST00000151796.1
Fkbp4
FK506 binding protein 4
chr1_-_37496095 0.885 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr12_+_55398775 0.883 ENSMUST00000021412.8
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr18_+_67562387 0.857 ENSMUST00000163749.1
Gm17669
predicted gene, 17669
chr6_+_113604749 0.856 ENSMUST00000035725.5
Brk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr11_-_103344651 0.852 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr8_-_85080652 0.851 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr4_+_44012638 0.846 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr11_-_96916366 0.836 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr9_+_22003035 0.834 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr9_+_107563246 0.829 ENSMUST00000010198.3
Tusc2
tumor suppressor candidate 2
chr17_+_29268788 0.822 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr9_+_40801235 0.807 ENSMUST00000117870.1
ENSMUST00000117557.1
Hspa8

heat shock protein 8

chr5_-_92435114 0.801 ENSMUST00000135112.1
Nup54
nucleoporin 54
chr19_+_11770415 0.798 ENSMUST00000167199.1
Mrpl16
mitochondrial ribosomal protein L16
chr9_+_46273064 0.795 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
Zfp259


zinc finger protein 259


chr7_-_19271797 0.791 ENSMUST00000032561.8
Vasp
vasodilator-stimulated phosphoprotein
chr17_-_29347902 0.775 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr15_+_78877172 0.773 ENSMUST00000041587.7
Gga1
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr11_+_70130329 0.772 ENSMUST00000041550.5
ENSMUST00000165951.1
Mgl2

macrophage galactose N-acetyl-galactosamine specific lectin 2

chr17_+_35135695 0.771 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
Bag6


BCL2-associated athanogene 6


chr4_-_120815703 0.766 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr11_-_11627824 0.766 ENSMUST00000081896.4
4930512M02Rik
RIKEN cDNA 4930512M02 gene
chr4_-_133277730 0.763 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr9_+_20644851 0.760 ENSMUST00000161882.1
Ubl5
ubiquitin-like 5
chr10_-_117063764 0.759 ENSMUST00000047672.7
Cct2
chaperonin containing Tcp1, subunit 2 (beta)
chr2_+_180257373 0.749 ENSMUST00000059080.6
Rps21
ribosomal protein S21
chr7_+_43607169 0.741 ENSMUST00000120935.1
ENSMUST00000127765.1
ENSMUST00000032661.7
Zfp819


zinc finger protein 819


chr14_+_120749352 0.741 ENSMUST00000138893.2
Gm17613
predicted gene, 17613
chr13_+_30659999 0.740 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
Dusp22


dual specificity phosphatase 22


chr4_-_117887292 0.737 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr12_-_80260356 0.733 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr2_+_57238297 0.733 ENSMUST00000112618.2
ENSMUST00000028167.2
Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr17_+_74717743 0.725 ENSMUST00000024882.6
Ttc27
tetratricopeptide repeat domain 27
chr8_-_122432924 0.721 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr11_+_5955693 0.719 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr6_+_48684544 0.713 ENSMUST00000118802.1
Gimap4
GTPase, IMAP family member 4
chr9_+_20644792 0.709 ENSMUST00000162303.1
ENSMUST00000161486.1
Ubl5

ubiquitin-like 5

chr8_+_85080939 0.707 ENSMUST00000140621.1
BC056474
cDNA sequence BC056474
chr17_-_12916345 0.705 ENSMUST00000079121.3
Mrpl18
mitochondrial ribosomal protein L18
chr16_+_4756845 0.697 ENSMUST00000140367.1
ENSMUST00000118885.1
ENSMUST00000121529.1
Hmox2


heme oxygenase (decycling) 2


chr5_-_110839575 0.696 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr2_+_180710117 0.691 ENSMUST00000029090.2
Gid8
GID complex subunit 8 homolog (S. cerevisiae)
chr15_+_76368884 0.689 ENSMUST00000023213.6
Fam203a
family with sequence similarity 203, member A
chr17_+_35916541 0.671 ENSMUST00000087211.2
Ppp1r10
protein phosphatase 1, regulatory subunit 10
chr6_-_72362382 0.670 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
Rnf181


ring finger protein 181


chr9_+_109875541 0.667 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr1_+_33669816 0.666 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr19_-_6910088 0.659 ENSMUST00000025904.5
Prdx5
peroxiredoxin 5
chr7_-_5413145 0.659 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr19_-_6909599 0.651 ENSMUST00000173091.1
Prdx5
peroxiredoxin 5
chr7_-_126475082 0.651 ENSMUST00000032978.6
Sh2b1
SH2B adaptor protein 1
chr10_+_112172540 0.646 ENSMUST00000132994.1
Caps2
calcyphosphine 2
chr12_+_77238093 0.645 ENSMUST00000177595.1
ENSMUST00000171770.2
Fut8

fucosyltransferase 8

chr1_+_17601893 0.645 ENSMUST00000088476.2
Pi15
peptidase inhibitor 15
chr12_+_100110148 0.643 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr12_+_75308308 0.639 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr3_+_7612702 0.636 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr7_+_142460834 0.629 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr9_-_116175318 0.621 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr2_+_164805082 0.620 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr16_+_35154870 0.605 ENSMUST00000114913.1
Adcy5
adenylate cyclase 5
chr3_+_90079540 0.604 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr13_-_8038106 0.601 ENSMUST00000165220.2
Gm9742
predicted gene 9742
chr11_-_120151194 0.600 ENSMUST00000179094.1
ENSMUST00000103018.4
ENSMUST00000045402.7
ENSMUST00000076697.6
ENSMUST00000053692.8
Slc38a10




solute carrier family 38, member 10




chr5_+_145140362 0.598 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr11_-_17008647 0.590 ENSMUST00000102881.3
Plek
pleckstrin
chrX_+_20703906 0.587 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr9_-_110476637 0.585 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr11_-_120457936 0.583 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr5_+_114100308 0.583 ENSMUST00000031588.7
Usp30
ubiquitin specific peptidase 30
chr1_-_87573825 0.581 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.8 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
1.9 9.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.3 9.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
1.3 7.6 GO:0032796 uropod organization(GO:0032796)
1.2 5.8 GO:0015671 oxygen transport(GO:0015671)
1.0 3.1 GO:0016068 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.9 2.6 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.9 3.5 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.8 3.4 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.8 2.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.8 2.4 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.8 2.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.7 3.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.7 0.7 GO:1900426 positive regulation of defense response to bacterium(GO:1900426)
0.7 2.1 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.7 2.0 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.7 2.0 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.7 2.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.7 2.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.6 1.9 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.6 2.3 GO:0050904 diapedesis(GO:0050904)
0.5 2.1 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.5 1.0 GO:1900673 olefin metabolic process(GO:1900673)
0.4 7.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 1.3 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.4 2.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 0.8 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.4 1.2 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.4 6.7 GO:0030574 collagen catabolic process(GO:0030574)
0.4 3.3 GO:0071569 protein ufmylation(GO:0071569)
0.4 1.1 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.3 2.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 1.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 0.6 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.3 1.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.3 4.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 2.2 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.3 0.8 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.3 3.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 0.8 GO:1903054 lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334)
0.2 4.7 GO:0019835 cytolysis(GO:0019835)
0.2 0.7 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.2 0.9 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 0.7 GO:0000087 mitotic M phase(GO:0000087)
0.2 1.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.2 1.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 1.1 GO:0001955 blood vessel maturation(GO:0001955)
0.2 2.0 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2 0.7 GO:0006788 heme oxidation(GO:0006788)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 0.6 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.8 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 0.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.2 2.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.7 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.6 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 1.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 1.8 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.5 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1 0.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 1.7 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 1.0 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.8 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.2 GO:0015816 glycine transport(GO:0015816)
0.1 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.4 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) lung-associated mesenchyme development(GO:0060484)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.5 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.2 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.1 0.9 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 1.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.3 GO:0007035 vacuolar acidification(GO:0007035)
0.1 1.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 0.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.3 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.2 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.4 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 1.1 GO:0045116 protein neddylation(GO:0045116)
0.1 3.2 GO:0042255 ribosome assembly(GO:0042255)
0.1 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.4 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 3.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0010388 cullin deneddylation(GO:0010388)
0.0 2.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.8 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.0 1.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.0 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 3.9 GO:0006909 phagocytosis(GO:0006909)
0.0 0.5 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 1.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.9 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.0 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 1.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 1.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 1.2 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 1.3 GO:0035904 aorta development(GO:0035904)
0.0 0.8 GO:0001706 endoderm formation(GO:0001706)
0.0 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.5 GO:0002237 response to molecule of bacterial origin(GO:0002237) response to lipopolysaccharide(GO:0032496)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 1.5 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0006110 regulation of glycolytic process(GO:0006110)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.8 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 1.2 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 1.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.4 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.7 5.8 GO:0005833 hemoglobin complex(GO:0005833)
0.6 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 2.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 2.0 GO:1990745 EARP complex(GO:1990745)
0.3 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 3.1 GO:0030008 TRAPP complex(GO:0030008)
0.3 2.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 7.6 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.1 GO:0032127 dense core granule membrane(GO:0032127)
0.3 0.8 GO:0043202 lysosomal lumen(GO:0043202)
0.3 3.8 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0044307 dendritic branch(GO:0044307)
0.2 15.3 GO:0005581 collagen trimer(GO:0005581)
0.2 2.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 0.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 2.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.8 GO:0071439 clathrin complex(GO:0071439)
0.2 1.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 5.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.7 GO:0097441 basilar dendrite(GO:0097441)
0.1 2.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.5 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.5 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 5.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.0 GO:0034709 methylosome(GO:0034709)
0.1 0.3 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 2.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.4 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.9 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 5.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 2.4 GO:0001772 immunological synapse(GO:0001772)
0.1 15.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 10.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 8.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 2.0 GO:0030315 T-tubule(GO:0030315)
0.0 1.3 GO:0005776 autophagosome(GO:0005776)
0.0 3.6 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.0 GO:0005884 actin filament(GO:0005884)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0005770 late endosome(GO:0005770)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 2.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.1 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 12.9 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 14.9 GO:0019864 IgG binding(GO:0019864)
1.4 9.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.2 5.8 GO:0005344 oxygen transporter activity(GO:0005344)
1.1 4.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 0.8 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.8 3.9 GO:0045503 dynein light chain binding(GO:0045503)
0.8 7.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 3.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5 1.5 GO:0005118 sevenless binding(GO:0005118)
0.5 0.5 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.5 2.4 GO:0051425 PTB domain binding(GO:0051425)
0.4 3.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 2.6 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.4 1.3 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.3 1.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 1.0 GO:0034952 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity(GO:0008694) 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity(GO:0018791) bis(4-chlorophenyl)acetate decarboxylase activity(GO:0018792) 3,5-dibromo-4-hydroxybenzoate decarboxylase activity(GO:0018793) 2-hydroxyisobutyrate decarboxylase activity(GO:0018794) 2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity(GO:0018795) 2-hydroxyisophthalate decarboxylase activity(GO:0034524) dimethylmalonate decarboxylase activity(GO:0034782) 2,4,4-trimethyl-3-oxopentanoate decarboxylase activity(GO:0034853) 4,4-dimethyl-3-oxopentanoate decarboxylase activity(GO:0034854) 2,3,6-trihydroxyisonicotinate decarboxylase activity(GO:0034879) phenanthrene-4,5-dicarboxylate decarboxylase activity(GO:0034923) pyrrole-2-carboxylate decarboxylase activity(GO:0034941) terephthalate decarboxylase activity(GO:0034947) malonate semialdehyde decarboxylase activity(GO:0034952) 5-amino-4-imidazole carboxylate lyase activity(GO:0043727) 2-keto-4-methylthiobutyrate aminotransferase activity(GO:0043728) 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity(GO:0051997)
0.3 0.6 GO:0046921 alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 1.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 1.8 GO:0016936 galactoside binding(GO:0016936)
0.3 0.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.3 1.4 GO:0070051 fibrinogen binding(GO:0070051)
0.3 2.0 GO:0031432 titin binding(GO:0031432)
0.3 2.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.7 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.2 2.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.0 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.2 2.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 1.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 4.4 GO:0001968 fibronectin binding(GO:0001968)
0.2 0.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.5 GO:0071568 UFM1 transferase activity(GO:0071568)
0.2 0.9 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.2 0.5 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 2.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.5 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.8 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.8 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.5 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1 2.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 4.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.1 GO:0017166 vinculin binding(GO:0017166)
0.1 1.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0016595 glutamate binding(GO:0016595)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.4 GO:0046790 virion binding(GO:0046790)
0.1 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618)
0.0 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 7.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 2.2 GO:0005125 cytokine activity(GO:0005125)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 1.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 2.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)