Motif ID: Stat1

Z-value: 0.793


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_52119499-0.453.5e-04Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_80802789 10.225 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr6_+_115134899 7.792 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chrX_-_61185558 7.679 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr4_-_64046925 7.502 ENSMUST00000107377.3
Tnc
tenascin C
chr7_+_45783883 6.393 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr7_+_45783686 6.225 ENSMUST00000118564.1
ENSMUST00000133428.1
Lmtk3

lemur tyrosine kinase 3

chr16_-_42340595 5.227 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr2_+_178193075 5.132 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr10_+_69925766 4.807 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr19_-_46327121 4.777 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr18_-_33463615 4.734 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr16_-_74411776 4.428 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr9_-_96719404 4.381 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr4_+_43401232 4.351 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr18_-_33463747 4.299 ENSMUST00000171533.1
Nrep
neuronal regeneration related protein
chr10_+_69925954 4.255 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr2_-_168712853 4.106 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr9_+_107296682 4.059 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr18_-_33464007 3.931 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr3_-_10440054 3.874 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr10_+_40349265 3.855 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr8_-_70776650 3.854 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr9_+_107296843 3.720 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr1_-_155417283 3.639 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr1_-_155417394 3.520 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr10_-_95417099 3.501 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr10_-_95416850 3.446 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr13_+_109903089 3.411 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr9_-_96719549 3.333 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr18_+_37320374 3.151 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr10_+_69925800 3.149 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr9_+_20868628 3.031 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr12_+_74297474 2.811 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr19_-_37207293 2.742 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr15_-_93519499 2.597 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr7_+_24112314 2.359 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr3_+_96576984 2.332 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr7_-_45016224 2.257 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chr10_-_18023229 2.253 ENSMUST00000020002.7
Abracl
ABRA C-terminal like
chr11_+_77765588 2.236 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr7_+_24134148 2.189 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr7_+_29768552 2.189 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr11_+_78499087 2.182 ENSMUST00000017488.4
Vtn
vitronectin
chr13_-_34002740 2.100 ENSMUST00000167237.1
ENSMUST00000168400.1
Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

chr11_+_82035569 1.940 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr9_+_54538984 1.937 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr7_+_29816061 1.877 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr8_+_70673364 1.711 ENSMUST00000146972.1
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_-_18234930 1.690 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr7_-_24316590 1.623 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr8_-_70608261 1.621 ENSMUST00000049908.9
Ssbp4
single stranded DNA binding protein 4
chr4_+_148140699 1.610 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr16_-_20426322 1.600 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chrX_+_7728439 1.546 ENSMUST00000033489.7
Praf2
PRA1 domain family 2
chr11_+_101425068 1.538 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr11_-_98729374 1.517 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr7_-_78577771 1.496 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr8_+_105326354 1.488 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr13_-_67755132 1.480 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr11_+_82101836 1.479 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr4_-_136886187 1.473 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr4_+_83417715 1.441 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr1_+_34005872 1.410 ENSMUST00000182296.1
Dst
dystonin
chr1_-_64121456 1.395 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr6_+_127446819 1.392 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chrX_+_48623737 1.391 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_-_105399991 1.376 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr8_+_11728105 1.375 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr13_-_67755192 1.364 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr11_+_101245996 1.344 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr16_+_17508947 1.315 ENSMUST00000023444.3
Lztr1
leucine-zipper-like transcriptional regulator, 1
chr6_+_29468068 1.307 ENSMUST00000143101.1
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr4_-_11965699 1.295 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr16_+_91372783 1.283 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr4_-_108032069 1.230 ENSMUST00000106709.2
Podn
podocan
chr2_+_3424123 1.222 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr9_+_32224457 1.199 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr12_+_11265867 1.186 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr11_-_106579111 1.126 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chr7_+_65693447 1.103 ENSMUST00000143508.1
Tm2d3
TM2 domain containing 3
chr2_-_127584668 1.084 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chr16_-_20426375 1.069 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_-_70627008 1.051 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr2_-_37422869 1.039 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr14_+_84443553 1.027 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr5_-_123140135 1.021 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr9_+_45117813 1.004 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr11_-_101425330 0.984 ENSMUST00000103102.3
Ptges3l
prostaglandin E synthase 3 (cytosolic)-like
chr2_-_120970706 0.980 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr7_-_13053684 0.972 ENSMUST00000182490.1
Mzf1
myeloid zinc finger 1
chr4_-_108031938 0.967 ENSMUST00000106708.1
Podn
podocan
chr11_+_78536393 0.934 ENSMUST00000050366.8
ENSMUST00000108275.1
Ift20

intraflagellar transport 20

chr13_-_34002784 0.931 ENSMUST00000166354.1
ENSMUST00000076532.7
ENSMUST00000171034.1
Serpinb6a


serine (or cysteine) peptidase inhibitor, clade B, member 6a


chr1_-_172027251 0.919 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr16_+_91372865 0.901 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr5_+_14025305 0.893 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chrX_-_101419788 0.891 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr11_+_78536355 0.886 ENSMUST00000128788.1
Ift20
intraflagellar transport 20
chr16_-_35871544 0.849 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr2_+_101886249 0.846 ENSMUST00000028584.7
Commd9
COMM domain containing 9
chrX_-_47892396 0.825 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr17_+_34145231 0.819 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr1_+_37890477 0.819 ENSMUST00000027256.5
Mrpl30
mitochondrial ribosomal protein L30
chr7_+_82335732 0.813 ENSMUST00000173287.1
Adamtsl3
ADAMTS-like 3
chr1_-_64121389 0.752 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr7_+_28392916 0.688 ENSMUST00000003529.8
Paf1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr3_-_108210438 0.672 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr7_+_30095150 0.670 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr13_-_85288999 0.669 ENSMUST00000109552.2
Rasa1
RAS p21 protein activator 1
chr12_-_112671564 0.667 ENSMUST00000128300.2
Akt1
thymoma viral proto-oncogene 1
chr2_-_155729359 0.649 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr10_-_128409632 0.645 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
Nabp2




nucleic acid binding protein 2




chr2_-_66634952 0.611 ENSMUST00000100064.2
ENSMUST00000100063.2
Scn9a

sodium channel, voltage-gated, type IX, alpha

chr10_+_18235030 0.609 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chr1_+_136624901 0.592 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr2_+_150749036 0.566 ENSMUST00000094467.5
Entpd6
ectonucleoside triphosphate diphosphohydrolase 6
chr1_+_171213969 0.538 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3


nuclear receptor subfamily 1, group I, member 3


chr8_-_67910911 0.528 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr4_-_140617062 0.519 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_-_20425881 0.500 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr17_-_24527830 0.486 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr10_-_127041513 0.476 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr11_-_77787747 0.458 ENSMUST00000092883.2
Gm10277
predicted gene 10277
chr4_+_49521176 0.441 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr1_+_36307745 0.415 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr17_-_24527925 0.405 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr7_-_126625676 0.399 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr4_+_128759258 0.382 ENSMUST00000030585.7
A3galt2
alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr7_+_24270420 0.378 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr7_+_27591705 0.375 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr16_+_21794320 0.362 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr17_-_45592569 0.342 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr8_+_86745679 0.332 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chrX_-_8252304 0.302 ENSMUST00000115594.1
Ftsj1
FtsJ homolog 1 (E. coli)
chr4_+_11704439 0.295 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr1_-_159168642 0.285 ENSMUST00000077309.1
Gm4953
predicted pseudogene 4953
chr14_-_121915774 0.248 ENSMUST00000055475.7
Gpr18
G protein-coupled receptor 18
chr8_+_70673198 0.242 ENSMUST00000034311.8
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_148602527 0.218 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr18_+_42511496 0.205 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr5_-_34513892 0.201 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr9_+_86571965 0.189 ENSMUST00000034988.3
ENSMUST00000179212.1
Rwdd2a

RWD domain containing 2A

chr17_+_34187789 0.168 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_-_96293953 0.165 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr13_-_41847482 0.162 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr7_-_100856289 0.154 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr17_+_34187545 0.148 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_27728889 0.131 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr3_+_122245557 0.130 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit
chrX_-_8252334 0.129 ENSMUST00000115595.1
ENSMUST00000033513.3
Ftsj1

FtsJ homolog 1 (E. coli)

chr3_-_57294880 0.128 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr12_-_100520778 0.068 ENSMUST00000062957.6
Ttc7b
tetratricopeptide repeat domain 7B
chr17_-_45592485 0.063 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr8_+_25601591 0.031 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr10_-_127070254 0.021 ENSMUST00000060991.4
Tspan31
tetraspanin 31
chr3_-_90490975 0.019 ENSMUST00000149884.1
Snapin
SNAP-associated protein
chr15_-_54919961 0.015 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr15_-_78305603 0.015 ENSMUST00000096356.3
Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr3_+_142496924 0.010 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.5 4.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.2 7.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.1 12.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 2.7 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.9 5.2 GO:0016198 axon choice point recognition(GO:0016198)
0.9 2.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.5 1.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.5 1.5 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.5 10.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.5 1.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.4 2.2 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.4 1.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 1.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.4 1.1 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.3 6.9 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.3 1.0 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.3 7.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 3.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 3.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 2.2 GO:0097421 liver regeneration(GO:0097421)
0.2 0.6 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 5.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 1.0 GO:0046684 response to pyrethroid(GO:0046684)
0.2 5.2 GO:0034340 response to type I interferon(GO:0034340)
0.2 1.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.2 0.5 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 0.7 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 12.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 3.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 12.3 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.1 1.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 4.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.2 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 3.9 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.8 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 4.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 2.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.6 GO:0032026 response to magnesium ion(GO:0032026)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.7 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.4 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 1.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 1.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.6 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.1 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.6 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 4.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.4 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.7 GO:0007266 Rho protein signal transduction(GO:0007266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 1.9 GO:0044299 C-fiber(GO:0044299)
0.6 3.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.5 10.2 GO:0032279 asymmetric synapse(GO:0032279)
0.5 7.5 GO:0005614 interstitial matrix(GO:0005614)
0.5 1.8 GO:1902636 kinociliary basal body(GO:1902636)
0.4 2.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 1.2 GO:0035061 interchromatin granule(GO:0035061)
0.4 1.4 GO:0031673 H zone(GO:0031673)
0.3 5.2 GO:0031527 filopodium membrane(GO:0031527)
0.2 0.8 GO:0090537 CERF complex(GO:0090537)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 1.4 GO:0000322 storage vacuole(GO:0000322)
0.2 4.4 GO:0030673 axolemma(GO:0030673)
0.2 2.0 GO:0005688 U6 snRNP(GO:0005688)
0.2 2.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 7.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 3.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 3.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.2 GO:0016459 myosin complex(GO:0016459)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 4.1 GO:0055037 recycling endosome(GO:0055037)
0.0 2.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.4 6.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.3 7.5 GO:0045545 syndecan binding(GO:0045545)
0.9 7.2 GO:0001618 virus receptor activity(GO:0001618)
0.9 5.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.9 3.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 4.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 3.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 2.2 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) interleukin-20 binding(GO:0042015)
0.4 12.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 1.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 7.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 5.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.3 1.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 0.8 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.2 2.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 4.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.0 GO:0070728 leucine binding(GO:0070728)
0.2 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 5.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 8.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 3.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.1 1.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.7 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 3.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 7.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.8 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.1 2.2 GO:0043531 ADP binding(GO:0043531)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 3.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 3.0 GO:0002020 protease binding(GO:0002020)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 8.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)