Motif ID: Stat1

Z-value: 0.793


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_52119499-0.453.5e-04Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Showing 1 to 20 of 159 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_80802789 10.225 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr6_+_115134899 7.792 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chrX_-_61185558 7.679 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr4_-_64046925 7.502 ENSMUST00000107377.3
 Tnc
tenascin C
chr7_+_45783883 6.393 ENSMUST00000072580.5
 Lmtk3
lemur tyrosine kinase 3
chr7_+_45783686 6.225 ENSMUST00000118564.1
ENSMUST00000133428.1
 Lmtk3

lemur tyrosine kinase 3

chr16_-_42340595 5.227 ENSMUST00000102817.4
 Gap43
growth associated protein 43
chr2_+_178193075 5.132 ENSMUST00000103065.1
 Phactr3
phosphatase and actin regulator 3
chr10_+_69925766 4.807 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
 Ank3


ankyrin 3, epithelial


chr19_-_46327121 4.777 ENSMUST00000041391.4
ENSMUST00000096029.5
 Psd

pleckstrin and Sec7 domain containing

chr18_-_33463615 4.734 ENSMUST00000051087.8
 Nrep
neuronal regeneration related protein
chr16_-_74411776 4.428 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr9_-_96719404 4.381 ENSMUST00000140121.1
 Zbtb38
zinc finger and BTB domain containing 38
chr4_+_43401232 4.351 ENSMUST00000125399.1
 Rusc2
RUN and SH3 domain containing 2
chr18_-_33463747 4.299 ENSMUST00000171533.1
 Nrep
neuronal regeneration related protein
chr10_+_69925954 4.255 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
 Ank3


ankyrin 3, epithelial


chr2_-_168712853 4.106 ENSMUST00000123156.1
ENSMUST00000156555.1
 Atp9a

ATPase, class II, type 9A

chr9_+_107296682 4.059 ENSMUST00000168260.1
 Cish
cytokine inducible SH2-containing protein
chr18_-_33464007 3.931 ENSMUST00000168890.1
 Nrep
neuronal regeneration related protein
chr3_-_10440054 3.874 ENSMUST00000099223.4
ENSMUST00000029047.6
 Snx16

sorting nexin 16


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 12.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 12.3 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
1.1 12.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 10.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 7.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
1.9 7.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.2 7.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 6.9 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 5.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.9 5.2 GO:0016198 axon choice point recognition(GO:0016198)
0.2 5.2 GO:0034340 response to type I interferon(GO:0034340)
1.5 4.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 4.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 4.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.1 4.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.3 3.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 3.9 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.3 3.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 3.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.9 2.7 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 13.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 10.2 GO:0032279 asymmetric synapse(GO:0032279)
0.2 7.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 7.5 GO:0005614 interstitial matrix(GO:0005614)
0.3 5.2 GO:0031527 filopodium membrane(GO:0031527)
0.2 4.4 GO:0030673 axolemma(GO:0030673)
0.0 4.1 GO:0055037 recycling endosome(GO:0055037)
0.6 3.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 3.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 2.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.4 2.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 2.2 GO:0016459 myosin complex(GO:0016459)
0.2 2.0 GO:0005688 U6 snRNP(GO:0005688)
0.6 1.9 GO:0044299 C-fiber(GO:0044299)
0.5 1.8 GO:1902636 kinociliary basal body(GO:1902636)
0.4 1.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.4 1.4 GO:0031673 H zone(GO:0031673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 12.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.7 10.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 8.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 8.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 7.7 GO:0008327 methyl-CpG binding(GO:0008327)
1.3 7.5 GO:0045545 syndecan binding(GO:0045545)
0.9 7.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 7.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
1.4 6.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 5.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.9 5.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 5.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.6 4.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 4.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.6 3.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 3.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 3.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.9 3.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 3.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)