Motif ID: Stat2
Z-value: 2.416

Transcription factors associated with Stat2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Stat2 | ENSMUSG00000040033.9 | Stat2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Stat2 | mm10_v2_chr10_+_128270546_128270577 | 0.64 | 4.6e-08 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 104 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 39.0 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
1.3 | 38.9 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
2.4 | 37.9 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
6.7 | 33.3 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
10.7 | 32.1 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
1.0 | 27.7 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.5 | 25.0 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
0.5 | 20.8 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
6.9 | 20.7 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
2.6 | 20.4 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
2.4 | 16.8 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
5.5 | 16.6 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
1.2 | 16.2 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
2.1 | 14.8 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
3.6 | 14.5 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
4.7 | 14.0 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
4.4 | 13.3 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
1.8 | 12.8 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
1.2 | 12.4 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
2.0 | 12.1 | GO:0010528 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 53 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 88.4 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 71.6 | GO:0016021 | integral component of membrane(GO:0016021) |
0.4 | 39.1 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 38.4 | GO:0005739 | mitochondrion(GO:0005739) |
0.1 | 33.3 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.8 | 33.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 22.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
1.9 | 20.8 | GO:0043083 | synaptic cleft(GO:0043083) |
0.3 | 14.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
1.2 | 13.7 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 13.0 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
1.1 | 12.4 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.1 | 11.6 | GO:0032587 | ruffle membrane(GO:0032587) |
3.7 | 11.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
1.5 | 10.7 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.0 | 9.6 | GO:0005829 | cytosol(GO:0005829) |
0.5 | 8.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 8.0 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 7.7 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 7.7 | GO:0016324 | apical plasma membrane(GO:0016324) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 90 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 43.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
2.9 | 37.9 | GO:0016443 | bidentate ribonuclease III activity(GO:0016443) |
8.3 | 33.3 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.1 | 33.3 | GO:0005525 | GTP binding(GO:0005525) |
1.4 | 33.1 | GO:0005521 | lamin binding(GO:0005521) |
10.7 | 32.1 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
0.1 | 24.4 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
3.0 | 20.8 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
1.6 | 20.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.9 | 18.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.2 | 15.8 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
1.6 | 14.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
2.8 | 14.0 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
0.2 | 13.7 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.2 | 13.4 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
1.0 | 12.4 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.9 | 12.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
3.0 | 12.1 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
0.5 | 12.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.3 | 11.5 | GO:0070412 | R-SMAD binding(GO:0070412) |