Motif ID: Stat2

Z-value: 2.416


Transcription factors associated with Stat2:

Gene SymbolEntrez IDGene Name
Stat2 ENSMUSG00000040033.9 Stat2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat2mm10_v2_chr10_+_128270546_1282705770.644.6e-08Click!


Activity profile for motif Stat2.

activity profile for motif Stat2


Sorted Z-values histogram for motif Stat2

Sorted Z-values for motif Stat2



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_103434211 33.077 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr7_-_141010759 32.283 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr6_+_90550789 32.131 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr16_+_23609895 20.720 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr16_+_26581704 20.404 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
Il1rap



interleukin 1 receptor accessory protein



chr2_-_51972990 16.563 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr8_-_84773381 16.156 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr3_+_81932601 15.752 ENSMUST00000029649.2
Ctso
cathepsin O
chr1_-_173942445 15.129 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr1_-_170110491 14.754 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr15_-_66812593 14.077 ENSMUST00000100572.3
Sla
src-like adaptor
chr18_+_61045139 14.016 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chrX_+_166238901 12.759 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr16_-_22439719 12.556 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr6_-_39118211 12.515 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr10_-_94944578 12.450 ENSMUST00000099337.3
Plxnc1
plexin C1
chr11_+_88999376 12.293 ENSMUST00000100627.2
ENSMUST00000107896.3
ENSMUST00000000284.6
Trim25


tripartite motif-containing 25


chr11_+_119393060 11.804 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr16_+_42907563 11.783 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr18_-_39489776 11.749 ENSMUST00000025300.6
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr3_-_137981523 11.562 ENSMUST00000136613.1
ENSMUST00000029806.6
Dapp1

dual adaptor for phosphotyrosine and 3-phosphoinositides 1

chr6_+_57580992 11.360 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr18_-_39490649 11.220 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr3_-_107760221 11.087 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr1_+_153751946 11.011 ENSMUST00000183241.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chrX_+_41401304 10.996 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr1_+_153751859 10.797 ENSMUST00000182538.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr4_+_45972233 10.707 ENSMUST00000102929.1
Tdrd7
tudor domain containing 7
chr18_-_39489880 10.312 ENSMUST00000152853.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr16_+_43363855 9.950 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr4_+_138972885 9.929 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4


transmembrane and coiled-coil domains 4


chr8_-_45333189 9.864 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chrX_+_41401128 9.766 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr10_+_13966268 9.035 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr11_+_31872100 8.909 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr18_-_78142119 8.872 ENSMUST00000160639.1
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr13_+_96924674 8.674 ENSMUST00000171324.1
Gcnt4
glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
chr9_-_58158498 8.459 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr18_+_69593361 8.419 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr12_-_78980758 8.294 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr1_+_153749496 8.115 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr16_+_43235856 8.095 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_-_156674290 7.983 ENSMUST00000079625.4
Tor3a
torsin family 3, member A
chr1_+_153749414 7.966 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr5_+_107497762 7.931 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr11_-_48871408 7.798 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr9_+_20868628 7.688 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr12_+_26469204 7.680 ENSMUST00000020969.3
Cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr10_+_40629987 7.670 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr17_+_86167777 7.543 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr11_-_48871344 7.322 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr7_+_107567445 7.064 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr2_-_173276144 6.998 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr10_-_30655859 6.975 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr7_-_78578308 6.927 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr12_+_90738201 6.872 ENSMUST00000181874.1
Gm26512
predicted gene, 26512
chr5_+_107497718 6.802 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr4_-_40239779 6.659 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr16_+_43364145 6.443 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr15_+_79892397 6.362 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr11_-_70459957 6.187 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr13_+_49504774 6.054 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr1_+_132008285 5.782 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr11_-_47379405 5.760 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr15_+_79892436 5.723 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr9_-_78443204 5.522 ENSMUST00000070742.7
ENSMUST00000034898.7
Mb21d1

Mab-21 domain containing 1

chr17_+_33919332 5.486 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr3_+_60501252 5.310 ENSMUST00000099087.2
Mbnl1
muscleblind-like 1 (Drosophila)
chr4_-_154636831 5.210 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr3_-_32616479 5.187 ENSMUST00000108234.1
ENSMUST00000155737.1
Gnb4

guanine nucleotide binding protein (G protein), beta 4

chr16_+_24393350 5.163 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr11_+_88718442 5.156 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr13_+_74639866 5.124 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr11_+_72689997 5.064 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr6_-_13839916 5.052 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr3_+_142560108 4.961 ENSMUST00000128609.1
ENSMUST00000029935.7
Gbp3

guanylate binding protein 3

chr4_-_40239700 4.956 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_+_39612934 4.740 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr18_+_37725706 4.694 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr9_+_118040576 4.683 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chr3_+_142560052 4.668 ENSMUST00000106222.2
Gbp3
guanylate binding protein 3
chr2_+_4559742 4.604 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr19_+_56397100 4.592 ENSMUST00000026062.9
Casp7
caspase 7
chr2_-_45110336 4.539 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr6_+_86404336 4.530 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr9_+_118040475 4.502 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr9_-_117252450 4.450 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr9_+_118478182 4.334 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr8_-_105938384 4.299 ENSMUST00000034369.8
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr3_+_94954075 4.285 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
Rfx5





regulatory factor X, 5 (influences HLA class II expression)





chr9_+_118040509 4.240 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chr14_+_28511344 4.235 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chrX_-_139998519 4.224 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
Rbm41



RNA binding motif protein 41



chr2_-_51934644 4.199 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr12_+_104406704 4.187 ENSMUST00000021506.5
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr12_+_37241633 4.157 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr11_+_29463735 4.141 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr1_-_9748376 4.118 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr2_-_51934943 4.117 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr9_+_118478344 4.117 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr3_+_142560351 4.095 ENSMUST00000106221.1
Gbp3
guanylate binding protein 3
chr18_+_37400845 4.077 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr6_+_121245903 4.039 ENSMUST00000032198.9
Usp18
ubiquitin specific peptidase 18
chr12_+_52699297 3.967 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr1_+_180942452 3.957 ENSMUST00000027800.8
Tmem63a
transmembrane protein 63a
chr8_+_95534078 3.951 ENSMUST00000041569.3
Ccdc113
coiled-coil domain containing 113
chr7_+_30121915 3.934 ENSMUST00000098596.3
ENSMUST00000153792.1
Zfp382

zinc finger protein 382

chr3_+_127791374 3.888 ENSMUST00000171621.1
Tifa
TRAF-interacting protein with forkhead-associated domain
chr5_-_92348871 3.806 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr13_-_23710714 3.728 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr12_-_79007276 3.725 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr11_+_70459940 3.644 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr16_-_24393588 3.542 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr3_+_19957037 3.482 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr7_-_46795881 3.430 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr13_+_37345338 3.395 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr3_+_114030532 3.159 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr2_+_31572775 3.117 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr16_-_44139630 3.076 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr16_+_35938470 2.981 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chrX_+_42150672 2.861 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr13_+_109260481 2.782 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr2_+_91650169 2.726 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr7_+_46796088 2.677 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chr2_-_62646146 2.665 ENSMUST00000112459.3
ENSMUST00000028259.5
Ifih1

interferon induced with helicase C domain 1

chr11_+_69846665 2.656 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr13_+_14063776 2.634 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr2_+_91650116 2.632 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr7_+_78578830 2.620 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr10_+_128270546 2.580 ENSMUST00000105238.3
ENSMUST00000085708.2
Stat2

signal transducer and activator of transcription 2

chr7_-_46795661 2.572 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr5_-_73256555 2.505 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr13_+_42866247 2.502 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr1_+_167618246 2.422 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr1_-_184732616 2.388 ENSMUST00000048572.6
Hlx
H2.0-like homeobox
chr11_+_69846610 2.380 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr11_-_82991829 2.377 ENSMUST00000092840.4
ENSMUST00000038211.5
Slfn9

schlafen 9

chr1_-_155972887 2.373 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr19_-_29367294 2.337 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr19_+_36409719 2.207 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr3_-_59262825 2.190 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_-_167062981 2.131 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr19_-_4477447 2.082 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr4_-_156200818 2.075 ENSMUST00000085425.4
Isg15
ISG15 ubiquitin-like modifier
chr4_+_105789869 2.048 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr17_+_29660710 1.965 ENSMUST00000130423.1
Cmtr1
cap methyltransferase 1
chr2_-_132111440 1.930 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr2_-_91649785 1.924 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr6_+_127446819 1.922 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr11_-_118401826 1.901 ENSMUST00000106290.3
ENSMUST00000043722.3
Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr1_+_66175286 1.855 ENSMUST00000114017.1
ENSMUST00000114015.1
Map2

microtubule-associated protein 2

chr2_-_167062607 1.766 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr16_+_35938972 1.760 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr9_+_32116040 1.748 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr8_-_122551316 1.747 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr5_-_137116177 1.696 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr17_+_33955812 1.644 ENSMUST00000025178.9
ENSMUST00000114330.2
Vps52

vacuolar protein sorting 52 (yeast)

chr8_+_46739745 1.572 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr18_+_60212080 1.564 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chrX_+_42151002 1.556 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr1_+_143640664 1.552 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr9_+_92542223 1.546 ENSMUST00000070522.7
ENSMUST00000160359.1
Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chr1_+_66175272 1.537 ENSMUST00000156636.2
Map2
microtubule-associated protein 2
chr7_+_44836286 1.537 ENSMUST00000033015.7
Il4i1
interleukin 4 induced 1
chr16_+_8470763 1.482 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22


methyltransferase like 22


chr19_+_12460749 1.469 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr9_-_103761820 1.453 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr16_-_44139003 1.434 ENSMUST00000124102.1
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr18_+_38296635 1.383 ENSMUST00000072376.5
ENSMUST00000170811.1
Rnf14

ring finger protein 14

chr5_-_90223923 1.363 ENSMUST00000118816.1
ENSMUST00000048363.7
Cox18

cytochrome c oxidase assembly protein 18

chr2_-_77946180 1.333 ENSMUST00000111824.1
ENSMUST00000111819.1
ENSMUST00000128963.1
Cwc22


CWC22 spliceosome-associated protein homolog (S. cerevisiae)


chr2_-_156857946 1.311 ENSMUST00000099141.2
4930518I15Rik
RIKEN cDNA 4930518I15 gene
chr16_-_35871544 1.204 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr3_+_89730735 1.099 ENSMUST00000107405.2
ENSMUST00000029563.8
ENSMUST00000121094.1
ENSMUST00000118341.1
Adar



adenosine deaminase, RNA-specific



chr2_+_31572701 1.079 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3
chr10_-_121586730 1.068 ENSMUST00000020316.2
Tbk1
TANK-binding kinase 1
chrX_+_109095359 1.026 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr6_-_125231772 1.017 ENSMUST00000043422.7
Tapbpl
TAP binding protein-like
chr2_-_77946331 1.002 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr8_-_71537402 0.947 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr2_+_31572651 0.943 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr2_+_155382186 0.920 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr3_+_58525821 0.909 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr4_+_108834601 0.905 ENSMUST00000030296.8
Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr11_+_72301613 0.813 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1


XIAP associated factor 1


chr1_-_52190901 0.808 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr16_-_44139196 0.761 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr2_-_91649751 0.752 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chr2_-_77946375 0.745 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr19_-_21472552 0.721 ENSMUST00000087600.3
Gda
guanine deaminase
chr17_-_78882508 0.693 ENSMUST00000024884.4
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr6_+_71543900 0.649 ENSMUST00000065364.2
Chmp3
charged multivesicular body protein 3
chr9_-_58249702 0.640 ENSMUST00000135310.1
ENSMUST00000085673.4
ENSMUST00000114136.2
ENSMUST00000153820.1
ENSMUST00000124982.1
Pml




promyelocytic leukemia




chr9_+_19641224 0.600 ENSMUST00000079042.6
Zfp317
zinc finger protein 317
chr9_-_58249660 0.563 ENSMUST00000124063.1
ENSMUST00000126690.1
Pml

promyelocytic leukemia

chr8_+_67494843 0.530 ENSMUST00000093470.5
ENSMUST00000163856.1
Nat2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

chr6_+_71543797 0.510 ENSMUST00000059462.5
Chmp3
charged multivesicular body protein 3
chr6_+_112696772 0.484 ENSMUST00000180959.1
Gm26799
predicted gene, 26799
chr2_-_36136602 0.465 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr1_+_85650008 0.458 ENSMUST00000054279.8
ENSMUST00000147552.1
ENSMUST00000153574.1
ENSMUST00000150967.1
Sp100



nuclear antigen Sp100




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.1 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
6.9 20.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
6.7 33.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
5.5 16.6 GO:1902524 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524)
4.7 14.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
4.4 13.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
3.6 14.5 GO:0044565 dendritic cell proliferation(GO:0044565)
2.9 11.6 GO:0009597 detection of virus(GO:0009597)
2.8 8.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.6 7.7 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
2.6 7.7 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
2.6 20.4 GO:0072602 interleukin-4 secretion(GO:0072602)
2.4 16.8 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.4 37.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
2.3 6.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
2.1 14.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
2.1 39.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
2.0 12.1 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
2.0 7.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
1.8 12.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.7 8.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
1.6 4.7 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
1.4 7.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
1.3 38.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.3 3.8 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.3 8.9 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
1.3 5.1 GO:0032439 endosome localization(GO:0032439)
1.2 12.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
1.2 11.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.2 16.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.0 4.0 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.0 27.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.9 8.4 GO:0042118 endothelial cell activation(GO:0042118)
0.9 4.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.8 4.1 GO:0090168 Golgi reassembly(GO:0090168)
0.8 5.5 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.8 4.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.7 5.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.7 2.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.7 5.5 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.6 9.7 GO:0034340 response to type I interferon(GO:0034340)
0.6 1.9 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.6 2.4 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.6 1.8 GO:0035456 response to interferon-beta(GO:0035456)
0.6 2.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.6 1.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 8.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.6 4.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.5 1.6 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.5 3.2 GO:0035989 tendon development(GO:0035989)
0.5 25.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.5 20.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.5 4.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 4.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.4 2.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.4 10.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.4 3.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.4 5.8 GO:0070932 histone H3 deacetylation(GO:0070932)
0.4 1.2 GO:0050713 negative regulation of interleukin-1 secretion(GO:0050711) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.4 3.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 2.8 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.3 2.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.3 2.5 GO:0090527 actin filament reorganization(GO:0090527)
0.3 3.5 GO:0046688 response to copper ion(GO:0046688)
0.2 4.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.2 0.7 GO:0046098 guanine metabolic process(GO:0046098)
0.2 4.2 GO:0006953 acute-phase response(GO:0006953)
0.2 1.4 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.2 4.7 GO:0001783 B cell apoptotic process(GO:0001783)
0.2 1.2 GO:0051036 regulation of endosome size(GO:0051036)
0.2 0.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 4.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 5.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 9.1 GO:0019395 fatty acid oxidation(GO:0019395)
0.1 5.0 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 2.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 2.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 2.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.1 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 1.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 11.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 4.6 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085) late viral transcription(GO:0019086)
0.0 2.7 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 3.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.9 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 1.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 5.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 5.8 GO:0060047 heart contraction(GO:0060047)
0.0 2.6 GO:0007286 spermatid development(GO:0007286)
0.0 5.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 3.9 GO:0042384 cilium assembly(GO:0042384)
0.0 1.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 6.6 GO:0006914 autophagy(GO:0006914)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 1.0 GO:0045727 positive regulation of translation(GO:0045727)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.9 20.8 GO:0043083 synaptic cleft(GO:0043083)
1.5 10.7 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
1.5 6.0 GO:0031084 BLOC-2 complex(GO:0031084)
1.4 5.8 GO:0016012 sarcoglycan complex(GO:0016012)
1.2 13.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
1.1 4.5 GO:0097165 nuclear stress granule(GO:0097165)
1.1 12.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.8 3.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.8 33.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.7 3.7 GO:1990357 terminal web(GO:1990357)
0.7 5.1 GO:0042825 TAP complex(GO:0042825)
0.6 5.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 5.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 8.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 39.1 GO:0016363 nuclear matrix(GO:0016363)
0.4 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.4 3.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.6 GO:1990745 EARP complex(GO:1990745)
0.3 2.7 GO:0000439 core TFIIH complex(GO:0000439)
0.3 14.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 4.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 88.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 7.0 GO:0031901 early endosome membrane(GO:0031901)
0.2 1.2 GO:0000815 ESCRT III complex(GO:0000815)
0.2 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 4.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 2.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 4.0 GO:0034451 centriolar satellite(GO:0034451)
0.2 2.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 11.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 33.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 2.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 7.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 8.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 7.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0005771 multivesicular body(GO:0005771)
0.0 2.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 22.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 38.4 GO:0005739 mitochondrion(GO:0005739)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.9 GO:0005643 nuclear pore(GO:0005643)
0.0 13.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 71.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 2.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 9.6 GO:0005829 cytosol(GO:0005829)
0.0 1.0 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
8.3 33.3 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
3.0 12.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
3.0 20.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.9 37.9 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
2.8 14.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
2.6 7.7 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
2.1 8.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.0 6.1 GO:0070052 collagen V binding(GO:0070052)
1.9 7.7 GO:0003884 D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922)
1.9 7.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.6 14.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.6 20.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.5 8.9 GO:0015265 urea channel activity(GO:0015265)
1.4 33.1 GO:0005521 lamin binding(GO:0005521)
1.4 4.2 GO:0005110 frizzled-2 binding(GO:0005110)
1.4 6.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.3 3.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.1 4.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.1 5.3 GO:0001069 regulatory region RNA binding(GO:0001069)
1.0 9.9 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
1.0 12.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.9 12.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.9 18.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.9 5.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.7 3.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 1.9 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.6 5.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 6.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.6 4.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.6 8.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.5 2.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.5 12.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5 1.5 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.5 4.0 GO:0043495 protein anchor(GO:0043495)
0.5 4.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.5 3.7 GO:0039706 co-receptor binding(GO:0039706)
0.4 3.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.4 4.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.4 1.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3 11.5 GO:0070412 R-SMAD binding(GO:0070412)
0.3 5.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 2.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 0.9 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.3 43.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 11.4 GO:0030332 cyclin binding(GO:0030332)
0.2 2.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 15.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 4.1 GO:0043422 protein kinase B binding(GO:0043422)
0.2 1.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 4.6 GO:0003924 GTPase activity(GO:0003924)
0.2 13.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 2.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 13.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.2 2.1 GO:0031386 protein tag(GO:0031386)
0.2 4.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 4.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 4.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 8.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 11.1 GO:0008083 growth factor activity(GO:0008083)
0.1 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 10.7 GO:0003729 mRNA binding(GO:0003729)
0.1 33.3 GO:0005525 GTP binding(GO:0005525)
0.1 24.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 4.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.8 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 9.8 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 5.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 3.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 7.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 8.5 GO:0016887 ATPase activity(GO:0016887)
0.0 0.1 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.0 1.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.5 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 1.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)