Motif ID: Stat5a

Z-value: 1.282


Transcription factors associated with Stat5a:

Gene SymbolEntrez IDGene Name
Stat5a ENSMUSG00000004043.8 Stat5a



Activity profile for motif Stat5a.

activity profile for motif Stat5a


Sorted Z-values histogram for motif Stat5a

Sorted Z-values for motif Stat5a



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat5a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_42583628 10.045 ENSMUST00000019938.4
 Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr7_-_103853199 9.442 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr6_+_4755327 8.077 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr9_+_92250039 7.628 ENSMUST00000093801.3
 Plscr1
phospholipid scramblase 1
chr9_-_79977782 7.534 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr7_+_88278085 6.758 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr2_-_168767136 6.650 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr9_-_114564315 6.563 ENSMUST00000111816.2
 Trim71
tripartite motif-containing 71
chr10_+_22158566 6.293 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr14_-_48665098 6.286 ENSMUST00000118578.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr7_+_107567445 6.284 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr2_-_80447625 6.207 ENSMUST00000028389.3
 Frzb
frizzled-related protein
chr3_-_25212720 6.184 ENSMUST00000091289.3
 Gm10259
predicted pseudogene 10259
chr2_+_5845243 6.146 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr17_-_25797032 5.933 ENSMUST00000165838.1
ENSMUST00000002344.6
 Metrn

meteorin, glial cell differentiation regulator

chr7_-_144939823 5.904 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr10_+_84838143 5.850 ENSMUST00000095388.4
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr6_+_138141569 5.759 ENSMUST00000118091.1
 Mgst1
microsomal glutathione S-transferase 1
chr15_-_103366763 5.549 ENSMUST00000023128.6
 Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr11_+_69964758 5.529 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
 Cldn7


claudin 7



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 502 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 19.7 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.7 13.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.8 11.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.8 11.5 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
2.6 10.6 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 9.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.5 9.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.9 9.4 GO:0015671 oxygen transport(GO:0015671)
1.8 9.1 GO:0021764 amygdala development(GO:0021764)
1.7 8.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.9 8.3 GO:0097421 liver regeneration(GO:0097421)
0.9 8.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.4 7.9 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
2.5 7.6 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
1.8 7.3 GO:0046061 dATP catabolic process(GO:0046061)
1.6 6.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.1 6.2 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.5 6.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.2 6.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.5 5.9 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 221 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 20.7 GO:0072562 blood microparticle(GO:0072562)
0.4 20.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 19.1 GO:0005615 extracellular space(GO:0005615)
0.1 18.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 16.8 GO:0031012 extracellular matrix(GO:0031012)
0.7 13.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 11.8 GO:0005667 transcription factor complex(GO:0005667)
0.4 10.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.8 9.8 GO:0042612 MHC class I protein complex(GO:0042612)
1.2 9.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 8.9 GO:0015934 large ribosomal subunit(GO:0015934)
2.1 8.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 8.0 GO:0000791 euchromatin(GO:0000791)
1.5 7.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 6.8 GO:0005581 collagen trimer(GO:0005581)
0.1 6.7 GO:0000922 spindle pole(GO:0000922)
2.1 6.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.3 5.9 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 5.8 GO:0032420 stereocilium(GO:0032420)
0.1 5.6 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 330 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.4 GO:0005198 structural molecule activity(GO:0005198)
0.3 14.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 13.8 GO:0005178 integrin binding(GO:0005178)
0.2 10.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
1.3 10.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.5 10.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 10.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
2.4 9.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.7 9.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 8.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.9 8.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.8 8.3 GO:0019992 diacylglycerol binding(GO:0019992)
2.7 8.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 7.7 GO:0008201 heparin binding(GO:0008201)
1.0 7.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 7.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 7.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.3 6.2 GO:0004601 peroxidase activity(GO:0004601)
0.2 6.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 6.0 GO:0030332 cyclin binding(GO:0030332)