Motif ID: Tbp

Z-value: 2.110


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.401.5e-03Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 25.374 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr3_+_87948666 23.083 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_-_103843154 14.289 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr11_+_94936224 11.529 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr1_-_138842429 10.513 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr1_-_171196229 9.243 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr17_+_24720063 8.757 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr7_-_142899985 8.666 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr2_-_164857542 8.657 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr1_+_109993982 7.423 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr13_+_23763660 7.382 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr13_+_21717626 7.051 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr4_+_136143497 6.619 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr19_-_53589067 6.116 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr13_-_21780616 6.070 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr6_+_4747306 6.054 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr4_+_116685859 6.013 ENSMUST00000129315.1
ENSMUST00000106470.1
Prdx1

peroxiredoxin 1

chr10_+_79988584 5.968 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr17_-_34000257 5.866 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr3_-_145649970 5.829 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.9 39.7 GO:0015671 oxygen transport(GO:0015671)
1.2 37.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 23.8 GO:0006334 nucleosome assembly(GO:0006334)
1.8 23.1 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
1.6 11.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 11.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
2.6 10.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.1 10.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 10.1 GO:0046688 response to copper ion(GO:0046688)
2.2 8.8 GO:0006407 rRNA export from nucleus(GO:0006407)
0.6 8.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.5 8.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
2.2 8.7 GO:0042414 epinephrine metabolic process(GO:0042414)
2.2 8.7 GO:0042360 vitamin E metabolic process(GO:0042360)
1.1 8.7 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.8 8.0 GO:0010992 ubiquitin homeostasis(GO:0010992)
1.3 7.5 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 7.2 GO:0007067 mitotic nuclear division(GO:0007067)
0.3 7.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 6.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.0 48.4 GO:0005833 hemoglobin complex(GO:0005833)
0.9 38.8 GO:0000786 nucleosome(GO:0000786)
0.9 32.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 25.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 18.1 GO:0043209 myelin sheath(GO:0043209)
0.6 16.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
3.8 11.5 GO:0005584 collagen type I trimer(GO:0005584)
1.5 10.2 GO:0097452 GAIT complex(GO:0097452)
0.1 9.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 8.8 GO:0005871 kinesin complex(GO:0005871)
0.3 8.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 8.7 GO:0005680 anaphase-promoting complex(GO:0005680)
2.5 7.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 7.5 GO:0000776 kinetochore(GO:0000776)
0.0 7.0 GO:0005802 trans-Golgi network(GO:0005802)
0.1 6.7 GO:0005882 intermediate filament(GO:0005882)
1.1 6.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 6.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 6.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 6.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
12.1 48.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 47.4 GO:0042393 histone binding(GO:0042393)
0.1 23.7 GO:0003735 structural constituent of ribosome(GO:0003735)
3.8 23.1 GO:0019841 retinol binding(GO:0019841)
1.7 20.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 16.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.8 11.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
3.4 10.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.3 8.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 8.8 GO:0003777 microtubule motor activity(GO:0003777)
1.4 8.7 GO:0035240 dopamine binding(GO:0035240)
0.9 8.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 7.5 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 6.9 GO:0005504 fatty acid binding(GO:0005504)
0.5 6.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.8 6.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 6.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 5.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 5.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 5.5 GO:0097602 cullin family protein binding(GO:0097602)