Motif ID: Tbx15

Z-value: 0.838


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_48045144 12.013 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr4_-_129121889 11.127 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr3_+_75557530 9.903 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr6_+_115134899 8.084 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr3_+_96181151 7.841 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr4_-_82505749 7.729 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr12_-_78980758 7.278 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr14_-_55116935 7.151 ENSMUST00000022819.5
Jph4
junctophilin 4
chrX_+_7919816 6.622 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr17_-_81649607 5.940 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr12_+_88953399 5.527 ENSMUST00000057634.7
Nrxn3
neurexin III
chr5_-_84417359 5.268 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr19_-_37207293 5.251 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr3_+_55461758 5.232 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr11_-_116654245 4.768 ENSMUST00000021166.5
Cygb
cytoglobin
chr3_-_82074639 4.747 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr18_-_42899294 4.689 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr16_-_23988852 4.684 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr8_+_84723003 4.558 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr9_-_58201705 4.510 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 162 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.1 15.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
4.0 12.0 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 9.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 8.8 GO:0006836 neurotransmitter transport(GO:0006836)
2.8 8.4 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.9 7.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 7.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.4 7.4 GO:0002021 response to dietary excess(GO:0002021)
2.4 7.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.3 6.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 6.2 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.5 6.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 6.0 GO:0035904 aorta development(GO:0035904)
1.2 5.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.8 5.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.5 5.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 5.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 5.3 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 5.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 5.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 15.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.5 15.2 GO:0044327 dendritic spine head(GO:0044327)
0.5 11.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 10.9 GO:0030673 axolemma(GO:0030673)
0.0 8.6 GO:0099503 secretory vesicle(GO:0099503)
0.0 8.4 GO:0030426 growth cone(GO:0030426)
0.8 7.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.4 7.2 GO:0030314 junctional membrane complex(GO:0030314)
0.1 6.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 6.8 GO:0030315 T-tubule(GO:0030315)
0.1 5.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 5.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 5.8 GO:0030175 filopodium(GO:0030175)
0.6 5.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 5.6 GO:0005814 centriole(GO:0005814)
0.3 5.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 5.0 GO:0042734 presynaptic membrane(GO:0042734)
0.2 4.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 4.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 4.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 13.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.6 12.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 11.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
1.3 10.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.4 9.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 7.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 7.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 7.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.8 7.6 GO:0004383 guanylate cyclase activity(GO:0004383)
2.4 7.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.5 6.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 6.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 6.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 6.2 GO:0019900 kinase binding(GO:0019900)
0.1 6.0 GO:0030276 clathrin binding(GO:0030276)
1.4 5.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 5.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 5.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 4.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.2 4.8 GO:0004096 catalase activity(GO:0004096)