Motif ID: Tbx1_Eomes
Z-value: 0.671
Transcription factors associated with Tbx1_Eomes:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Eomes | ENSMUSG00000032446.8 | Eomes |
| Tbx1 | ENSMUSG00000009097.9 | Tbx1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Eomes | mm10_v2_chr9_+_118478344_118478451 | 0.17 | 2.1e-01 | Click! |
Top targets:
Showing 1 to 20 of 163 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 82 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 6.5 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.4 | 4.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 4.2 | GO:0050807 | regulation of synapse organization(GO:0050807) |
| 1.3 | 4.0 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.8 | 4.0 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.4 | 3.9 | GO:0071493 | cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399) |
| 0.3 | 3.3 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.3 | 3.3 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 1.0 | 3.1 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.3 | 2.9 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.1 | 2.8 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 2.8 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.7 | 2.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.4 | 2.2 | GO:0030091 | protein repair(GO:0030091) |
| 0.7 | 2.1 | GO:2000852 | regulation of corticosterone secretion(GO:2000852) |
| 0.1 | 2.1 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.7 | 2.0 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
| 0.3 | 2.0 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.4 | 1.8 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
| 0.5 | 1.6 | GO:0051866 | general adaptation syndrome(GO:0051866) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 33 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0005884 | actin filament(GO:0005884) |
| 1.3 | 3.9 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.1 | 3.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.3 | 3.7 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 3.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 3.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 3.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 2.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.5 | 2.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 2.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 2.0 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 1.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.3 | 1.3 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 1.0 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.1 | 0.9 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.1 | 0.9 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.9 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.8 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.7 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 52 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.4 | 4.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.7 | 4.0 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.1 | 4.0 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 3.6 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 3.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.6 | 2.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.4 | 2.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 2.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 2.5 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.3 | 2.2 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 0.4 | 2.0 | GO:0071253 | connexin binding(GO:0071253) |
| 0.3 | 2.0 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
| 0.6 | 1.8 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.0 | 1.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 1.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.2 | 1.7 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 1.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.3 | 1.4 | GO:0042834 | peptidoglycan binding(GO:0042834) |
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