Motif ID: Tbx21

Z-value: 1.492


Transcription factors associated with Tbx21:

Gene SymbolEntrez IDGene Name
Tbx21 ENSMUSG00000001444.2 Tbx21



Activity profile for motif Tbx21.

activity profile for motif Tbx21


Sorted Z-values histogram for motif Tbx21

Sorted Z-values for motif Tbx21



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx21

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_56969827 21.140 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 20.401 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chrX_+_170009659 17.291 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr9_-_112185726 16.695 ENSMUST00000160240.1
ENSMUST00000162065.1
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_98180866 13.671 ENSMUST00000112959.1
 Prdm8
PR domain containing 8
chr7_+_45785331 13.011 ENSMUST00000120005.1
ENSMUST00000123585.1
 Lmtk3

lemur tyrosine kinase 3

chr11_+_24080664 12.935 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr18_+_37020097 12.297 ENSMUST00000047614.1
 Pcdha2
protocadherin alpha 2
chr9_-_112185939 12.245 ENSMUST00000070218.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr13_-_100108337 10.413 ENSMUST00000180822.1
 BC001981
cDNA sequence BC001981
chr5_-_39644597 9.978 ENSMUST00000152057.1
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr3_-_89322883 9.661 ENSMUST00000029673.5
 Efna3
ephrin A3
chr5_-_39644634 9.636 ENSMUST00000053116.6
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr9_-_106656081 9.564 ENSMUST00000023959.7
 Grm2
glutamate receptor, metabotropic 2
chr14_+_64588112 9.518 ENSMUST00000181808.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chr15_-_84105662 9.199 ENSMUST00000082365.5
 Sult4a1
sulfotransferase family 4A, member 1
chr7_-_126704816 7.657 ENSMUST00000032949.7
 Coro1a
coronin, actin binding protein 1A
chr8_+_12984246 7.446 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr6_-_60829826 7.281 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr11_+_22971991 7.098 ENSMUST00000049506.5
 Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr19_+_44989073 7.055 ENSMUST00000026225.8
 Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_+_62703667 6.987 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
 Nrp2



neuropilin 2



chr10_-_75560330 6.981 ENSMUST00000051129.9
 Fam211b
family with sequence similarity 211, member B
chr18_+_67088287 6.955 ENSMUST00000025402.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr7_-_4789541 6.797 ENSMUST00000168578.1
 Tmem238
transmembrane protein 238
chr6_-_101377897 6.516 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr18_+_37742088 6.502 ENSMUST00000003599.6
 Pcdhga9
protocadherin gamma subfamily A, 9
chr2_-_66440753 6.336 ENSMUST00000112371.2
ENSMUST00000138910.1
 Scn1a

sodium channel, voltage-gated, type I, alpha

chr1_+_62703285 6.246 ENSMUST00000102822.2
ENSMUST00000075144.5
 Nrp2

neuropilin 2

chr5_-_138619751 5.659 ENSMUST00000085852.4
ENSMUST00000110905.2
 Zfp68

zinc finger protein 68

chr10_-_13868932 5.569 ENSMUST00000019942.5
ENSMUST00000162610.1
 Aig1

androgen-induced 1

chr1_-_133131782 5.544 ENSMUST00000180528.1
 Gm26616
predicted gene, 26616
chr17_-_56074542 5.540 ENSMUST00000139371.1
 Ubxn6
UBX domain protein 6
chr1_+_59912972 5.395 ENSMUST00000036540.5
 Fam117b
family with sequence similarity 117, member B
chr3_-_127499095 5.287 ENSMUST00000182594.1
 Ank2
ankyrin 2, brain
chr6_-_38124568 5.247 ENSMUST00000040259.4
 Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chrX_+_74297097 4.891 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
 Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chr8_-_105701077 4.809 ENSMUST00000042608.6
 Acd
adrenocortical dysplasia
chr10_-_13868779 4.770 ENSMUST00000105534.3
 Aig1
androgen-induced 1
chr11_-_118248590 4.763 ENSMUST00000106305.2
 Cyth1
cytohesin 1
chr1_+_179546303 4.761 ENSMUST00000040706.8
 Cnst
consortin, connexin sorting protein
chr1_+_34801704 4.465 ENSMUST00000047664.9
 Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr2_+_28641227 4.451 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
 Tsc1


tuberous sclerosis 1


chr6_-_142964404 4.261 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr5_-_138619702 4.220 ENSMUST00000063262.4
 Zfp68
zinc finger protein 68
chr8_+_25849618 4.184 ENSMUST00000098858.3
 Kcnu1
potassium channel, subfamily U, member 1
chr5_-_138619653 4.149 ENSMUST00000129832.1
 Zfp68
zinc finger protein 68
chr17_-_33713372 4.132 ENSMUST00000173392.1
 March2
membrane-associated ring finger (C3HC4) 2
chr12_-_87233556 4.056 ENSMUST00000021423.7
 Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr5_-_36582381 4.020 ENSMUST00000141043.1
ENSMUST00000031094.8
 Tbc1d14

TBC1 domain family, member 14

chr2_-_167043494 4.017 ENSMUST00000067584.6
 Znfx1
zinc finger, NFX1-type containing 1
chr14_+_54426902 3.439 ENSMUST00000010550.7
 Mrpl52
mitochondrial ribosomal protein L52
chr11_+_103171081 3.408 ENSMUST00000042286.5
 Fmnl1
formin-like 1
chr4_-_155669171 3.310 ENSMUST00000103176.3
 Mib2
mindbomb homolog 2 (Drosophila)
chr9_-_35558522 3.256 ENSMUST00000034612.5
 Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr11_+_88047302 3.169 ENSMUST00000139129.2
 Srsf1
serine/arginine-rich splicing factor 1
chr10_+_7792891 3.060 ENSMUST00000015901.4
 Ppil4
peptidylprolyl isomerase (cyclophilin)-like 4
chrX_-_136868537 3.027 ENSMUST00000058814.6
 Rab9b
RAB9B, member RAS oncogene family
chr7_-_29954049 3.026 ENSMUST00000108211.1
ENSMUST00000108205.1
 Zfp74

zinc finger protein 74

chr6_-_50261943 3.023 ENSMUST00000167893.1
 Dfna5
deafness, autosomal dominant 5 (human)
chr7_-_27178835 3.000 ENSMUST00000093040.6
 Rab4b
RAB4B, member RAS oncogene family
chr19_-_6128208 2.888 ENSMUST00000025702.7
 Snx15
sorting nexin 15
chr8_+_105701142 2.835 ENSMUST00000098444.2
 Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr11_-_65162904 2.682 ENSMUST00000093002.5
ENSMUST00000047463.8
 Arhgap44

Rho GTPase activating protein 44

chr6_-_50261743 2.597 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
 Dfna5


deafness, autosomal dominant 5 (human)


chr9_-_86546795 2.556 ENSMUST00000167814.1
 Gm17530
predicted gene, 17530
chr6_+_83101565 2.312 ENSMUST00000101254.3
 Ccdc142
coiled-coil domain containing 142
chr4_+_74242468 2.304 ENSMUST00000077851.3
 Kdm4c
lysine (K)-specific demethylase 4C
chrX_+_99821021 2.249 ENSMUST00000096363.2
 Tmem28
transmembrane protein 28
chr3_-_94436574 2.234 ENSMUST00000029787.4
 Oaz3
ornithine decarboxylase antizyme 3
chr1_-_179546261 2.156 ENSMUST00000027769.5
 Tfb2m
transcription factor B2, mitochondrial
chr17_-_56074932 2.051 ENSMUST00000019722.5
 Ubxn6
UBX domain protein 6
chr16_-_4003750 2.019 ENSMUST00000171658.1
ENSMUST00000171762.1
 Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

chr11_-_120643643 2.009 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
 Pycr1




pyrroline-5-carboxylate reductase 1




chr19_+_5425121 1.974 ENSMUST00000159759.1
 AI837181
expressed sequence AI837181
chr13_+_104178797 1.941 ENSMUST00000022225.5
ENSMUST00000069187.5
 Trim23

tripartite motif-containing 23

chr9_-_117252450 1.919 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
 Rbms3


RNA binding motif, single stranded interacting protein


chr8_-_84822823 1.902 ENSMUST00000065539.4
 Dand5
DAN domain family, member 5
chr1_+_60409612 1.848 ENSMUST00000052332.8
 Abi2
abl-interactor 2
chr6_-_113377510 1.763 ENSMUST00000099118.2
 Tada3
transcriptional adaptor 3
chr16_-_20426322 1.751 ENSMUST00000115547.2
ENSMUST00000096199.4
 Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr9_-_85749308 1.579 ENSMUST00000039213.8
 Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr3_+_106684943 1.497 ENSMUST00000098751.3
 Lrif1
ligand dependent nuclear receptor interacting factor 1
chr4_-_117914968 1.480 ENSMUST00000036156.5
 Ipo13
importin 13
chr3_-_89402650 1.428 ENSMUST00000168325.1
ENSMUST00000057431.5
 Lenep

lens epithelial protein

chr7_-_13034722 1.403 ENSMUST00000005711.4
 Chmp2a
charged multivesicular body protein 2A
chr4_+_115563649 1.388 ENSMUST00000141033.1
ENSMUST00000030486.8
ENSMUST00000126645.1
ENSMUST00000030480.3
 Cyp4a31



cytochrome P450, family 4, subfamily a, polypeptide 31



chr1_+_153874335 1.388 ENSMUST00000055314.3
 Gm5531
predicted gene 5531
chr4_+_109000770 1.353 ENSMUST00000106644.2
 Nrd1
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr5_-_113989739 1.299 ENSMUST00000077689.7
 Ssh1
slingshot homolog 1 (Drosophila)
chr2_+_30364227 1.289 ENSMUST00000077977.7
ENSMUST00000140075.2
 Fam73b

family with sequence similarity 73, member B

chr17_+_6270475 1.273 ENSMUST00000088940.4
 Tmem181a
transmembrane protein 181A
chr13_+_54789500 1.239 ENSMUST00000163915.1
ENSMUST00000099503.3
ENSMUST00000171859.1
 Tspan17


tetraspanin 17


chr2_+_84678396 1.165 ENSMUST00000102645.3
 Med19
mediator of RNA polymerase II transcription, subunit 19 homolog (yeast)
chr12_+_73286868 1.165 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
 Slc38a6


solute carrier family 38, member 6


chr12_-_4874341 1.070 ENSMUST00000137337.1
ENSMUST00000045921.7
 Mfsd2b

major facilitator superfamily domain containing 2B

chr2_+_164823001 1.033 ENSMUST00000132282.1
 Zswim1
zinc finger SWIM-type containing 1
chr6_-_113377712 1.026 ENSMUST00000113107.1
ENSMUST00000113106.1
 Tada3

transcriptional adaptor 3

chr6_+_113378113 1.012 ENSMUST00000171058.1
ENSMUST00000156898.1
 Arpc4

actin related protein 2/3 complex, subunit 4

chr5_-_120777628 1.000 ENSMUST00000044833.8
 Oas3
2'-5' oligoadenylate synthetase 3
chr17_+_30485511 0.989 ENSMUST00000064223.1
 Gm9874
predicted gene 9874
chr10_-_62578387 0.957 ENSMUST00000162525.1
ENSMUST00000159704.1
ENSMUST00000162759.1
ENSMUST00000065887.7
 2510003E04Rik



RIKEN cDNA 2510003E04 gene



chr19_+_34192229 0.954 ENSMUST00000054956.8
 Stambpl1
STAM binding protein like 1
chr6_-_113377866 0.879 ENSMUST00000032410.7
 Tada3
transcriptional adaptor 3
chr12_-_113260217 0.819 ENSMUST00000178282.1
 Igha
immunoglobulin heavy constant alpha
chr7_+_27607997 0.784 ENSMUST00000142365.1
 Akt2
thymoma viral proto-oncogene 2
chr17_+_27029259 0.779 ENSMUST00000053683.6
 Ggnbp1
gametogenetin binding protein 1
chr11_-_118415794 0.777 ENSMUST00000164927.1
 Cant1
calcium activated nucleotidase 1
chr16_+_8470763 0.743 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
 Mettl22


methyltransferase like 22


chr16_+_75592844 0.722 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
 Rbm11


RNA binding motif protein 11


chr2_-_151973840 0.713 ENSMUST00000109865.1
ENSMUST00000109864.1
 Fam110a

family with sequence similarity 110, member A

chr17_-_24527830 0.676 ENSMUST00000176353.1
ENSMUST00000176237.1
 Traf7

TNF receptor-associated factor 7

chr12_+_73286779 0.675 ENSMUST00000140523.1
 Slc38a6
solute carrier family 38, member 6
chr2_+_55411790 0.637 ENSMUST00000155997.1
ENSMUST00000128307.1
 Gm14033

predicted gene 14033

chr17_-_24527925 0.594 ENSMUST00000176652.1
 Traf7
TNF receptor-associated factor 7
chr7_+_128062657 0.541 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
 Itgam


integrin alpha M


chr2_-_151973387 0.465 ENSMUST00000109863.1
 Fam110a
family with sequence similarity 110, member A
chr9_+_108049254 0.432 ENSMUST00000112295.2
ENSMUST00000047947.7
 Gmppb

GDP-mannose pyrophosphorylase B

chr1_+_92910758 0.400 ENSMUST00000027487.8
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr14_-_100149764 0.379 ENSMUST00000097079.4
 Klf12
Kruppel-like factor 12
chr11_-_74590186 0.356 ENSMUST00000102521.1
 Rap1gap2
RAP1 GTPase activating protein 2
chr6_+_90619241 0.349 ENSMUST00000032177.8
 Slc41a3
solute carrier family 41, member 3
chr2_-_37703845 0.346 ENSMUST00000155237.1
 Strbp
spermatid perinuclear RNA binding protein
chr3_+_137918526 0.346 ENSMUST00000168345.1
 Lamtor3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr9_+_55326913 0.342 ENSMUST00000085754.3
ENSMUST00000034862.4
 AI118078

expressed sequence AI118078

chr17_+_13760502 0.327 ENSMUST00000139347.1
ENSMUST00000156591.1
ENSMUST00000170827.2
ENSMUST00000139666.1
ENSMUST00000137784.1
ENSMUST00000137708.1
ENSMUST00000150848.1
 Mllt4






myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4






chr9_+_110419750 0.311 ENSMUST00000035061.6
 Ngp
neutrophilic granule protein
chr1_-_152090308 0.289 ENSMUST00000044581.7
 1700025G04Rik
RIKEN cDNA 1700025G04 gene
chr16_-_20425881 0.225 ENSMUST00000077867.3
 Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr13_-_8870999 0.184 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
 Wdr37


WD repeat domain 37


chr3_-_63964659 0.159 ENSMUST00000161659.1
 Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chrX_-_95444789 0.146 ENSMUST00000084535.5
 Amer1
APC membrane recruitment 1
chr18_-_42579652 0.140 ENSMUST00000054738.3
 Gpr151
G protein-coupled receptor 151
chr13_-_100650981 0.136 ENSMUST00000022136.6
ENSMUST00000177848.1
 Rad17

RAD17 homolog (S. pombe)

chr4_+_154869585 0.116 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
 Mmel1


membrane metallo-endopeptidase-like 1


chr10_-_39899238 0.108 ENSMUST00000178563.1
 AA474331
expressed sequence AA474331
chr1_-_135284075 0.039 ENSMUST00000077340.7
ENSMUST00000074357.7
 Rnpep

arginyl aminopeptidase (aminopeptidase B)

chr18_+_9958147 0.007 ENSMUST00000025137.7
 Thoc1
THO complex 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
2.6 41.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.8 7.3 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
1.6 4.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
1.6 4.8 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
1.6 4.8 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
1.5 4.5 GO:0043379 memory T cell differentiation(GO:0043379)
1.3 7.7 GO:0032796 uropod organization(GO:0032796)
1.0 12.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.0 13.7 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.9 5.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070)
0.8 33.2 GO:0034605 cellular response to heat(GO:0034605)
0.8 6.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.7 2.0 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.7 4.0 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.6 6.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.6 7.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.6 5.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 2.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.5 1.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.4 1.3 GO:0009405 pathogenesis(GO:0009405)
0.4 3.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.4 3.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.4 3.4 GO:0051014 actin filament severing(GO:0051014)
0.4 7.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 1.9 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 9.6 GO:0014047 glutamate secretion(GO:0014047)
0.2 2.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 2.3 GO:0033169 histone H3-K9 demethylation(GO:0033169) regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 1.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 9.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.2 4.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 7.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 13.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.3 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.0 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 3.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 5.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 1.5 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.1 1.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 5.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.8 GO:0002385 mucosal immune response(GO:0002385)
0.1 1.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 4.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 3.3 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.8 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 3.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 9.2 GO:0008202 steroid metabolic process(GO:0008202)
0.0 1.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 3.1 GO:0046323 glucose import(GO:0046323)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 4.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 3.3 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.9 GO:0045727 positive regulation of translation(GO:0045727)
0.0 1.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 2.8 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 4.2 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.5 4.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.9 7.1 GO:0089701 U2AF(GO:0089701)
0.7 5.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 4.8 GO:0070187 telosome(GO:0070187)
0.7 2.0 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.5 4.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 3.3 GO:0033391 chromatoid body(GO:0033391)
0.4 6.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.4 41.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 1.3 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.3 7.7 GO:0001891 phagocytic cup(GO:0001891)
0.2 5.3 GO:0031430 M band(GO:0031430)
0.2 3.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 3.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 12.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 7.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 9.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 6.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 3.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 4.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 9.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 6.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 4.0 GO:0005776 autophagosome(GO:0005776)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 2.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 13.7 GO:0016604 nuclear body(GO:0016604)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 4.8 GO:0030133 transport vesicle(GO:0030133)
0.0 2.7 GO:0031256 leading edge membrane(GO:0031256)
0.0 10.5 GO:0030424 axon(GO:0030424)
0.0 3.3 GO:0005769 early endosome(GO:0005769)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 5.9 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 13.7 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 19.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.3 7.0 GO:0050827 toxin receptor binding(GO:0050827)
1.9 9.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.9 13.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.7 13.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.5 6.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.4 4.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.2 7.3 GO:0050544 arachidonic acid binding(GO:0050544)
1.0 4.8 GO:0071253 connexin binding(GO:0071253)
0.8 7.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 4.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.6 1.9 GO:0016015 morphogen activity(GO:0016015)
0.6 2.2 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.4 4.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 5.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 2.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 1.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.4 7.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 9.2 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.3 7.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.3 3.2 GO:0050733 RS domain binding(GO:0050733)
0.3 6.3 GO:0031402 sodium ion binding(GO:0031402)
0.3 4.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 2.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 1.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 7.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 9.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 5.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 4.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 28.9 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 3.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.0 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 12.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.0 GO:0019003 GDP binding(GO:0019003)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 3.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.4 GO:0008905 mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 1.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
0.0 30.6 GO:0003682 chromatin binding(GO:0003682)
0.0 1.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 12.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 2.9 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) DNA-methyltransferase activity(GO:0009008) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 9.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 16.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 4.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)