Motif ID: Tbx21

Z-value: 1.492


Transcription factors associated with Tbx21:

Gene SymbolEntrez IDGene Name
Tbx21 ENSMUSG00000001444.2 Tbx21



Activity profile for motif Tbx21.

activity profile for motif Tbx21


Sorted Z-values histogram for motif Tbx21

Sorted Z-values for motif Tbx21



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx21

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 138 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56969827 21.140 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 20.401 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chrX_+_170009659 17.291 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr9_-_112185726 16.695 ENSMUST00000160240.1
ENSMUST00000162065.1
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_98180866 13.671 ENSMUST00000112959.1
 Prdm8
PR domain containing 8
chr7_+_45785331 13.011 ENSMUST00000120005.1
ENSMUST00000123585.1
 Lmtk3

lemur tyrosine kinase 3

chr11_+_24080664 12.935 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr18_+_37020097 12.297 ENSMUST00000047614.1
 Pcdha2
protocadherin alpha 2
chr9_-_112185939 12.245 ENSMUST00000070218.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr13_-_100108337 10.413 ENSMUST00000180822.1
 BC001981
cDNA sequence BC001981
chr5_-_39644597 9.978 ENSMUST00000152057.1
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr3_-_89322883 9.661 ENSMUST00000029673.5
 Efna3
ephrin A3
chr5_-_39644634 9.636 ENSMUST00000053116.6
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr9_-_106656081 9.564 ENSMUST00000023959.7
 Grm2
glutamate receptor, metabotropic 2
chr14_+_64588112 9.518 ENSMUST00000181808.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chr15_-_84105662 9.199 ENSMUST00000082365.5
 Sult4a1
sulfotransferase family 4A, member 1
chr7_-_126704816 7.657 ENSMUST00000032949.7
 Coro1a
coronin, actin binding protein 1A
chr8_+_12984246 7.446 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr6_-_60829826 7.281 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr11_+_22971991 7.098 ENSMUST00000049506.5
 Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 41.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.8 33.2 GO:0034605 cellular response to heat(GO:0034605)
1.0 13.7 GO:0021540 corpus callosum morphogenesis(GO:0021540)
4.4 13.2 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.2 13.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
1.0 12.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 9.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 9.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 9.2 GO:0008202 steroid metabolic process(GO:0008202)
1.3 7.7 GO:0032796 uropod organization(GO:0032796)
0.4 7.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
1.8 7.3 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
0.2 7.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.6 7.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.6 6.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.8 6.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 5.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 5.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.6 5.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.9 5.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 41.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 13.7 GO:0016604 nuclear body(GO:0016604)
0.0 13.7 GO:0005794 Golgi apparatus(GO:0005794)
0.2 12.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 10.5 GO:0030424 axon(GO:0030424)
0.1 9.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 9.6 GO:0042734 presynaptic membrane(GO:0042734)
0.3 7.7 GO:0001891 phagocytic cup(GO:0001891)
1.8 7.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.9 7.1 GO:0089701 U2AF(GO:0089701)
0.1 7.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 6.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.4 6.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 5.9 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.1 5.6 GO:0031594 neuromuscular junction(GO:0031594)
0.2 5.3 GO:0031430 M band(GO:0031430)
0.7 5.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.5 4.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7 4.8 GO:0070187 telosome(GO:0070187)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 30.6 GO:0003682 chromatin binding(GO:0003682)
0.1 28.9 GO:0005516 calmodulin binding(GO:0005516)
3.3 19.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 16.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
1.7 13.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.9 13.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 12.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 12.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.2 9.7 GO:0046875 ephrin receptor binding(GO:0046875)
1.9 9.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.4 9.2 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 9.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.3 7.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.8 7.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 7.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
1.2 7.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 7.1 GO:0030215 semaphorin receptor binding(GO:0030215)
2.3 7.0 GO:0050827 toxin receptor binding(GO:0050827)
0.3 6.3 GO:0031402 sodium ion binding(GO:0031402)
1.5 6.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)