Motif ID: Tbx3

Z-value: 0.339


Transcription factors associated with Tbx3:

Gene SymbolEntrez IDGene Name
Tbx3 ENSMUSG00000018604.12 Tbx3



Activity profile for motif Tbx3.

activity profile for motif Tbx3


Sorted Z-values histogram for motif Tbx3

Sorted Z-values for motif Tbx3



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_56377300 2.754 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr7_-_4522427 1.813 ENSMUST00000098859.3
 Tnni3
troponin I, cardiac 3
chr17_-_59013264 1.650 ENSMUST00000174122.1
ENSMUST00000025065.5
 Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr7_-_4522794 1.641 ENSMUST00000140424.1
 Tnni3
troponin I, cardiac 3
chr10_+_127514939 1.513 ENSMUST00000035735.9
 Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr7_+_107567445 1.328 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr11_-_94507337 1.113 ENSMUST00000040692.8
 Mycbpap
MYCBP associated protein
chr14_+_67745229 1.101 ENSMUST00000111095.2
 Gnrh1
gonadotropin releasing hormone 1
chr1_-_31222604 1.085 ENSMUST00000127775.1
 4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr1_+_93215899 0.979 ENSMUST00000138595.1
 E030010N08Rik
RIKEN cDNA E030010N08 gene
chr7_-_118443549 0.698 ENSMUST00000081574.4
 Syt17
synaptotagmin XVII
chr11_-_100970887 0.623 ENSMUST00000060792.5
 Ptrf
polymerase I and transcript release factor
chr4_+_135759705 0.529 ENSMUST00000105854.1
 Myom3
myomesin family, member 3
chr6_-_97060407 0.490 ENSMUST00000089295.4
 Fam19a4
family with sequence similarity 19, member A4
chrX_-_20931520 0.363 ENSMUST00000001156.7
 Cfp
complement factor properdin
chr13_+_108046411 0.285 ENSMUST00000095458.4
 Smim15
small integral membrane protein 15
chr19_+_7494033 0.239 ENSMUST00000170373.1
 Atl3
atlastin GTPase 3
chr5_-_106926245 0.129 ENSMUST00000117588.1
 Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr3_+_89246397 0.108 ENSMUST00000168900.1
 Krtcap2
keratinocyte associated protein 2
chr18_-_23981555 0.092 ENSMUST00000115829.1
 Zscan30
zinc finger and SCAN domain containing 30
chr12_+_84361636 0.086 ENSMUST00000110276.1
 Coq6
coenzyme Q6 homolog (yeast)
chr7_-_28949670 0.048 ENSMUST00000148196.1
 Actn4
actinin alpha 4
chr12_+_84361968 0.016 ENSMUST00000021661.6
 Coq6
coenzyme Q6 homolog (yeast)
chr10_+_80226644 0.004 ENSMUST00000130260.1
 Mum1
melanoma associated antigen (mutated) 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.6 3.5 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.4 1.7 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.1 0.6 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.7 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.5 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0005861 troponin complex(GO:0005861)
0.3 2.8 GO:0005916 fascia adherens(GO:0005916)
0.2 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.5 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0030172 troponin C binding(GO:0030172)
0.6 2.8 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)