Motif ID: Tbx4

Z-value: 1.352


Transcription factors associated with Tbx4:

Gene SymbolEntrez IDGene Name
Tbx4 ENSMUSG00000000094.6 Tbx4



Activity profile for motif Tbx4.

activity profile for motif Tbx4


Sorted Z-values histogram for motif Tbx4

Sorted Z-values for motif Tbx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_134018829 23.539 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr2_+_164562579 20.178 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr10_+_26229707 19.247 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr9_-_43239816 16.138 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr1_+_6730051 15.998 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr14_-_70642268 14.315 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr10_-_120899067 12.939 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr6_-_94700137 12.148 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr12_+_3891728 10.404 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr1_+_6730135 9.934 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr10_-_127341583 9.013 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr1_-_138847579 8.700 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr11_-_94507337 8.471 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr17_+_29093763 8.463 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr6_+_15196949 8.457 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr7_-_100658394 8.280 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr5_+_115908644 8.221 ENSMUST00000141101.1
Cit
citron
chr4_+_11191726 8.025 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chr19_+_55894508 7.959 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chrX_-_53269020 7.862 ENSMUST00000114838.1
Fam122b
family with sequence similarity 122, member B
chr19_+_20601958 7.552 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr4_+_117849193 7.474 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr4_+_117849361 7.147 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_-_148045891 6.665 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr1_+_132316112 6.566 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chrX_+_100730178 6.376 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr11_+_78178105 6.302 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chr7_-_28302238 6.248 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr18_+_5591860 6.204 ENSMUST00000025081.5
ENSMUST00000159390.1
Zeb1

zinc finger E-box binding homeobox 1

chrX_+_100729917 6.112 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_115824699 6.077 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr14_+_62292475 5.693 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr6_+_7555053 5.489 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr1_+_153665666 5.443 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr7_-_100658364 5.436 ENSMUST00000107043.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_103970221 5.424 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr8_+_45885479 5.276 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr1_+_153665274 5.273 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr2_+_103970115 5.132 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr9_-_95845215 5.060 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr13_-_96542479 4.911 ENSMUST00000022172.4
Polk
polymerase (DNA directed), kappa
chr9_-_69760924 4.911 ENSMUST00000071281.4
Foxb1
forkhead box B1
chr1_+_153665587 4.821 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr15_-_38300693 4.765 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr11_-_115813621 4.689 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr2_-_148046896 4.674 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr6_-_24956106 4.652 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr1_+_153665627 4.443 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr12_-_56345862 4.408 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr19_-_42202150 4.361 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chrX_+_101383726 4.126 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr4_+_11191354 3.820 ENSMUST00000170901.1
Ccne2
cyclin E2
chr10_-_86705485 3.375 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr9_+_108296853 3.228 ENSMUST00000035230.5
Amt
aminomethyltransferase
chr4_-_42168603 3.224 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr3_+_51415986 3.054 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr18_-_46212595 3.034 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chrX_+_42151002 3.022 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr1_+_66468364 3.021 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr14_-_51988829 2.941 ENSMUST00000181008.1
Gm16617
predicted gene, 16617
chr15_-_10470490 2.889 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chrX_+_169036610 2.876 ENSMUST00000087016.4
ENSMUST00000112129.1
ENSMUST00000112131.2
Arhgap6


Rho GTPase activating protein 6


chr11_+_23306884 2.868 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr7_-_141443989 2.769 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr13_-_89742490 2.705 ENSMUST00000109546.2
Vcan
versican
chr17_-_49564262 2.699 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr4_-_46404224 2.544 ENSMUST00000107764.2
Hemgn
hemogen
chr6_-_28261907 2.502 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr3_-_75556759 2.355 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
Pdcd10


programmed cell death 10


chr7_-_99858872 2.276 ENSMUST00000036274.6
Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr13_+_113209659 2.246 ENSMUST00000038144.8
Esm1
endothelial cell-specific molecule 1
chr2_+_54436317 2.152 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr6_+_42286676 2.073 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr10_-_85916902 2.072 ENSMUST00000037646.7
Prdm4
PR domain containing 4
chr5_+_120513102 1.998 ENSMUST00000111889.1
Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr4_-_72852622 1.956 ENSMUST00000179234.1
ENSMUST00000078617.4
Aldoart1

aldolase 1 A, retrogene 1

chr15_+_10952332 1.937 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr5_+_31094984 1.894 ENSMUST00000066505.1
Gm9924
predicted gene 9924
chr11_+_23306910 1.806 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr2_+_138278481 1.665 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr9_+_35421541 1.652 ENSMUST00000119129.2
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr13_+_96542727 1.643 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr10_+_86705811 1.641 ENSMUST00000061458.7
ENSMUST00000075632.6
BC030307

cDNA sequence BC030307

chr2_-_60125651 1.636 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr3_+_96629919 1.624 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr11_-_78751656 1.546 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr10_-_128211788 1.393 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr9_+_86743641 1.365 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr12_-_31634592 1.304 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr9_-_48495321 1.297 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr9_+_86743616 1.280 ENSMUST00000036426.6
Prss35
protease, serine, 35
chrM_+_9452 1.243 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chrX_+_20425688 1.197 ENSMUST00000115384.2
Phf16
PHD finger protein 16
chr6_+_42286709 1.195 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr16_-_84835484 0.978 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr3_-_121263314 0.848 ENSMUST00000029777.7
Tmem56
transmembrane protein 56
chr17_-_78937031 0.813 ENSMUST00000024885.8
Cebpz
CCAAT/enhancer binding protein zeta
chr2_-_30178422 0.795 ENSMUST00000100220.4
ENSMUST00000179795.1
D2Wsu81e

DNA segment, Chr 2, Wayne State University 81, expressed

chr11_+_78826575 0.775 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chr3_-_121263159 0.744 ENSMUST00000128909.1
Tmem56
transmembrane protein 56
chr14_+_31251454 0.584 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chr3_-_103791075 0.572 ENSMUST00000106845.2
ENSMUST00000029438.8
ENSMUST00000121324.1
Hipk1


homeodomain interacting protein kinase 1


chr16_+_62814676 0.495 ENSMUST00000055557.5
Stx19
syntaxin 19
chr11_-_106301801 0.478 ENSMUST00000103071.3
Gh
growth hormone
chrX_-_162829379 0.474 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
Txlng


taxilin gamma


chr4_-_36056726 0.455 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr9_+_44326804 0.431 ENSMUST00000054708.3
Dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr11_+_95414078 0.430 ENSMUST00000107724.2
ENSMUST00000150884.1
ENSMUST00000107722.1
ENSMUST00000127713.1
Spop



speckle-type POZ protein



chr8_+_79028587 0.418 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr13_+_93304066 0.386 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr7_-_46795661 0.376 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr11_-_22286795 0.280 ENSMUST00000109563.2
ENSMUST00000180360.1
Ehbp1

EH domain binding protein 1

chr16_-_9994921 0.221 ENSMUST00000115835.1
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr16_-_50330987 0.210 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr2_-_57114970 0.206 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr8_+_79028317 0.176 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr8_+_105636509 0.159 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr13_-_108158584 0.137 ENSMUST00000163558.1
Ndufaf2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
chr7_+_89980749 0.122 ENSMUST00000181784.1
Gm26529
predicted gene, 26529
chr13_-_111490028 0.047 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr13_+_96542602 0.043 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr3_-_103791537 0.011 ENSMUST00000118317.1
Hipk1
homeodomain interacting protein kinase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
4.0 12.1 GO:0032474 otolith morphogenesis(GO:0032474)
3.8 11.3 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
2.6 23.5 GO:0010587 miRNA catabolic process(GO:0010587)
2.6 12.9 GO:0030091 protein repair(GO:0030091)
2.3 9.0 GO:0060032 notochord regression(GO:0060032)
1.9 7.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.8 5.5 GO:2000852 regulation of corticosterone secretion(GO:2000852)
1.7 8.7 GO:0035262 gonad morphogenesis(GO:0035262)
1.7 5.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
1.5 20.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
1.5 4.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
1.3 10.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
1.2 6.2 GO:0007386 compartment pattern specification(GO:0007386)
1.2 12.5 GO:0090527 actin filament reorganization(GO:0090527)
1.2 4.9 GO:0007412 axon target recognition(GO:0007412)
1.1 3.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.0 8.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.9 8.5 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.8 10.6 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.7 8.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.7 4.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.7 6.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.6 2.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.6 1.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.6 2.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.6 6.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.5 8.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 3.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 3.4 GO:0071318 cellular response to ATP(GO:0071318)
0.4 11.8 GO:0006270 DNA replication initiation(GO:0006270)
0.3 3.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 1.9 GO:0071638 cellular triglyceride homeostasis(GO:0035356) adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3 3.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 5.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 2.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 6.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 2.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 14.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.2 5.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 2.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.2 1.5 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 3.2 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 2.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 2.3 GO:0006465 signal peptide processing(GO:0006465)
0.1 2.9 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.4 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 4.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.4 GO:0019348 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) dolichol metabolic process(GO:0019348)
0.0 2.7 GO:0008347 glial cell migration(GO:0008347)
0.0 2.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.1 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 2.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 5.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 5.1 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 2.5 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.5 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 2.1 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0070557 PCNA-p21 complex(GO:0070557)
1.0 5.1 GO:1990357 terminal web(GO:1990357)
0.9 5.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.9 8.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.8 2.3 GO:0005787 signal peptidase complex(GO:0005787)
0.7 9.0 GO:0097542 ciliary tip(GO:0097542)
0.5 20.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.5 10.4 GO:0001741 XY body(GO:0001741)
0.4 4.7 GO:0000124 SAGA complex(GO:0000124)
0.4 3.1 GO:0031415 NatA complex(GO:0031415)
0.4 23.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 4.1 GO:0005922 connexon complex(GO:0005922)
0.3 3.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 4.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 13.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.0 GO:0030061 mitochondrial crista(GO:0030061)
0.1 8.2 GO:0031985 Golgi cisterna(GO:0031985)
0.1 12.5 GO:0005884 actin filament(GO:0005884)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 3.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 20.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 5.7 GO:0030018 Z disc(GO:0030018)
0.0 3.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 11.0 GO:0098793 presynapse(GO:0098793)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 4.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.4 14.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
1.8 12.9 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
1.3 10.4 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
1.3 7.6 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.2 12.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.2 23.5 GO:0035198 miRNA binding(GO:0035198)
0.7 2.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.7 5.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6 8.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 2.0 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 20.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 3.4 GO:0046790 virion binding(GO:0046790)
0.4 13.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 20.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 16.8 GO:0070888 E-box binding(GO:0070888)
0.4 8.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 4.1 GO:0005243 gap junction channel activity(GO:0005243)
0.3 1.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.3 2.9 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.3 5.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 11.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 3.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 6.2 GO:0005112 Notch binding(GO:0005112)
0.2 3.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 4.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 4.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 2.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 3.2 GO:0008483 transaminase activity(GO:0008483)
0.1 9.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 8.8 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 8.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.5 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 13.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.1 GO:0051015 actin filament binding(GO:0051015)
0.0 3.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 6.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.9 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 28.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 2.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 4.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)