Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
Z-value: 1.122
Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bhlhe41 | ENSMUSG00000030256.5 | Bhlhe41 |
| Srebf1 | ENSMUSG00000020538.9 | Srebf1 |
| Srebf2 | ENSMUSG00000022463.7 | Srebf2 |
| Tfeb | ENSMUSG00000023990.12 | Tfeb |
| Usf1 | ENSMUSG00000026641.7 | Usf1 |
| Usf2 | ENSMUSG00000058239.7 | Usf2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tfeb | mm10_v2_chr17_+_47737030_47737107 | 0.66 | 1.7e-08 | Click! |
| Srebf1 | mm10_v2_chr11_-_60210410_60210465 | 0.59 | 9.4e-07 | Click! |
| Srebf2 | mm10_v2_chr15_+_82147238_82147275 | 0.36 | 4.9e-03 | Click! |
| Usf2 | mm10_v2_chr7_-_30956742_30956803 | 0.34 | 8.7e-03 | Click! |
| Usf1 | mm10_v2_chr1_+_171411305_171411337 | -0.14 | 2.8e-01 | Click! |
First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
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Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 18.0 | GO:1901254 | positive regulation of intracellular transport of viral material(GO:1901254) |
| 4.0 | 15.8 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 3.9 | 11.6 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
| 3.2 | 9.5 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 3.0 | 9.0 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
| 2.9 | 11.8 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 2.9 | 8.6 | GO:0043379 | memory T cell differentiation(GO:0043379) |
| 2.7 | 10.6 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 2.3 | 7.0 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 1.9 | 7.7 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) |
| 1.9 | 9.6 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 1.8 | 5.3 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566) |
| 1.7 | 5.0 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 1.6 | 11.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 1.5 | 3.1 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) |
| 1.5 | 12.2 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 1.5 | 7.5 | GO:1900170 | prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 1.3 | 3.9 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 1.3 | 3.8 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 1.3 | 5.1 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
| 1.1 | 3.4 | GO:0015889 | cobalamin transport(GO:0015889) |
| 1.1 | 8.0 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) |
| 1.1 | 5.5 | GO:1905049 | negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049) |
| 1.1 | 4.2 | GO:1900157 | regulation of bone mineralization involved in bone maturation(GO:1900157) |
| 1.1 | 5.3 | GO:0042117 | monocyte activation(GO:0042117) |
| 1.0 | 7.0 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 1.0 | 14.1 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 1.0 | 4.0 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 1.0 | 7.7 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.9 | 1.9 | GO:1900453 | negative regulation of long term synaptic depression(GO:1900453) |
| 0.9 | 3.8 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.9 | 2.8 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.9 | 1.7 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 0.9 | 4.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.8 | 3.4 | GO:0097494 | regulation of vesicle size(GO:0097494) |
| 0.8 | 5.0 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.8 | 4.0 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.8 | 5.6 | GO:0035826 | rubidium ion transport(GO:0035826) |
| 0.8 | 2.3 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.8 | 3.1 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.7 | 4.5 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.7 | 2.2 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
| 0.7 | 2.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.7 | 2.2 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.7 | 2.8 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.7 | 4.2 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.7 | 3.4 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.7 | 2.0 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
| 0.7 | 4.7 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
| 0.7 | 10.0 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.7 | 9.9 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.7 | 3.9 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.6 | 1.9 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
| 0.6 | 1.9 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679) |
| 0.6 | 6.0 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.6 | 13.3 | GO:0097576 | autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576) |
| 0.6 | 1.7 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.6 | 6.9 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.6 | 1.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.6 | 2.2 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055) |
| 0.6 | 2.2 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.6 | 3.3 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.5 | 2.7 | GO:0019530 | taurine metabolic process(GO:0019530) |
| 0.5 | 3.6 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
| 0.5 | 1.6 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.5 | 1.6 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.5 | 15.3 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.5 | 1.5 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.5 | 1.5 | GO:0090148 | membrane fission(GO:0090148) |
| 0.5 | 1.5 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.5 | 3.4 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.5 | 0.9 | GO:0042421 | norepinephrine biosynthetic process(GO:0042421) |
| 0.5 | 2.4 | GO:0006681 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
| 0.5 | 1.4 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) |
| 0.5 | 5.5 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.5 | 1.8 | GO:2000015 | regulation of determination of dorsal identity(GO:2000015) |
| 0.4 | 1.3 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
| 0.4 | 4.4 | GO:0006862 | nucleotide transport(GO:0006862) |
| 0.4 | 0.9 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 0.4 | 2.6 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.4 | 3.1 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.4 | 0.9 | GO:0040009 | regulation of growth rate(GO:0040009) |
| 0.4 | 4.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.4 | 3.5 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.4 | 0.4 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.4 | 1.7 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.4 | 4.2 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.4 | 1.7 | GO:1904426 | positive regulation of GTP binding(GO:1904426) regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.4 | 1.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.4 | 9.2 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.4 | 0.8 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.4 | 17.7 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.4 | 3.1 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.4 | 6.2 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.4 | 0.8 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.4 | 1.5 | GO:0033136 | pons maturation(GO:0021586) serine phosphorylation of STAT3 protein(GO:0033136) |
| 0.4 | 62.3 | GO:0008643 | carbohydrate transport(GO:0008643) |
| 0.4 | 1.5 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate proteoglycan metabolic process(GO:0050655) |
| 0.4 | 3.7 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.4 | 2.2 | GO:0071638 | positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.4 | 1.1 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.4 | 2.9 | GO:0015074 | DNA integration(GO:0015074) |
| 0.4 | 2.9 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.4 | 2.5 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.4 | 4.3 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.4 | 3.6 | GO:0043084 | penile erection(GO:0043084) |
| 0.4 | 0.7 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.3 | 1.4 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.3 | 3.4 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.3 | 3.8 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.3 | 9.2 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.3 | 1.4 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 0.3 | 2.0 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.3 | 6.3 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.3 | 5.2 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.3 | 1.9 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.3 | 3.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.3 | 3.4 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.3 | 3.3 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.3 | 1.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.3 | 0.6 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.3 | 0.9 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.3 | 9.5 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.3 | 3.5 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.3 | 0.6 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 0.3 | 5.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.3 | 2.3 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.3 | 0.8 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
| 0.3 | 1.4 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.3 | 0.8 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
| 0.3 | 2.4 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.3 | 0.8 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.3 | 7.5 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
| 0.3 | 0.8 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.3 | 1.3 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.3 | 3.9 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.3 | 0.5 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.2 | 1.7 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.2 | 1.2 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.2 | 1.5 | GO:1903887 | motile primary cilium assembly(GO:1903887) |
| 0.2 | 3.4 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.2 | 2.4 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.2 | 2.9 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.2 | 2.8 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.2 | 8.9 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
| 0.2 | 1.4 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.2 | 1.9 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.2 | 1.1 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.2 | 0.5 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.2 | 0.7 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.2 | 4.0 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.2 | 0.9 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.2 | 1.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.2 | 4.6 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.2 | 0.9 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.2 | 0.2 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
| 0.2 | 5.0 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.2 | 1.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.2 | 0.6 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.2 | 1.2 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.2 | 2.6 | GO:0048570 | notochord morphogenesis(GO:0048570) |
| 0.2 | 1.6 | GO:1901660 | calcium ion export(GO:1901660) |
| 0.2 | 5.8 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.2 | 8.0 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.2 | 10.0 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.2 | 0.9 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.2 | 2.5 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.2 | 1.6 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.2 | 0.9 | GO:0006513 | protein monoubiquitination(GO:0006513) |
| 0.2 | 0.7 | GO:0044332 | Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.2 | 0.7 | GO:1900026 | regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.2 | 1.9 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.2 | 0.5 | GO:2000224 | testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224) |
| 0.2 | 1.7 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.2 | 1.5 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.2 | 0.5 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.2 | 1.3 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.2 | 0.2 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
| 0.2 | 4.0 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.2 | 0.5 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.2 | 3.2 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.2 | 0.8 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.1 | 0.4 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.1 | 1.8 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.1 | 1.9 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.1 | 0.4 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 0.1 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
| 0.1 | 0.4 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
| 0.1 | 0.9 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.1 | 1.1 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.1 | 0.6 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.1 | 0.4 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.1 | 1.0 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.1 | 1.2 | GO:0051770 | positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770) |
| 0.1 | 3.2 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.1 | 11.0 | GO:0043473 | pigmentation(GO:0043473) |
| 0.1 | 0.4 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 0.1 | 0.5 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.1 | 1.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 0.6 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 2.4 | GO:0007032 | endosome organization(GO:0007032) |
| 0.1 | 8.7 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 1.5 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 0.6 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.1 | 1.3 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.1 | 0.6 | GO:0032682 | negative regulation of chemokine production(GO:0032682) |
| 0.1 | 5.2 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 3.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 4.1 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.1 | 0.6 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.1 | 0.1 | GO:1990379 | lipid transport across blood brain barrier(GO:1990379) |
| 0.1 | 0.2 | GO:0046958 | nonassociative learning(GO:0046958) habituation(GO:0046959) |
| 0.1 | 0.7 | GO:0044090 | positive regulation of vacuole organization(GO:0044090) |
| 0.1 | 1.2 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 4.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 1.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.3 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.1 | 0.5 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
| 0.1 | 0.3 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.2 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
| 0.1 | 5.6 | GO:0030203 | glycosaminoglycan metabolic process(GO:0030203) |
| 0.1 | 6.9 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 0.2 | GO:0061043 | regulation of vascular wound healing(GO:0061043) |
| 0.1 | 6.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 0.6 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.1 | 4.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 0.7 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.1 | 1.0 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 4.1 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.1 | 2.2 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.1 | 0.5 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 0.4 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.1 | 0.9 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.1 | 0.5 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.2 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 0.9 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.3 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.1 | 0.4 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.1 | 2.6 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 2.4 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.1 | 0.7 | GO:0030011 | maintenance of cell polarity(GO:0030011) |
| 0.1 | 1.0 | GO:0046697 | decidualization(GO:0046697) |
| 0.1 | 0.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.7 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
| 0.1 | 0.1 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.1 | 1.1 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 0.1 | 0.9 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.1 | 0.1 | GO:1903722 | regulation of centriole elongation(GO:1903722) |
| 0.1 | 2.3 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.1 | 0.7 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.5 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 0.5 | GO:0006544 | glycine metabolic process(GO:0006544) |
| 0.1 | 0.6 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.1 | 3.2 | GO:0006818 | hydrogen transport(GO:0006818) |
| 0.1 | 1.0 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 1.3 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.1 | 0.7 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 1.2 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 0.8 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.1 | 0.9 | GO:0010388 | protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388) |
| 0.1 | 1.1 | GO:0061154 | endothelial tube morphogenesis(GO:0061154) |
| 0.1 | 0.2 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
| 0.1 | 0.5 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.1 | 0.3 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.1 | 0.6 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.1 | 1.2 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.1 | 0.2 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 0.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.7 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.1 | 0.2 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 5.5 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
| 0.1 | 2.4 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.1 | 1.6 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 0.3 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 2.8 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 0.5 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.1 | 3.5 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.1 | 0.6 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 1.3 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 0.9 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.3 | GO:0045056 | transcytosis(GO:0045056) |
| 0.0 | 0.4 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.0 | 1.9 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.0 | 1.4 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 0.2 | GO:0090220 | meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
| 0.0 | 0.1 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.0 | 0.5 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.0 | 2.4 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.1 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 1.1 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.0 | 0.9 | GO:1901264 | carbohydrate derivative transport(GO:1901264) |
| 0.0 | 0.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.0 | 0.1 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.0 | 0.2 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.0 | 0.6 | GO:0060674 | placenta blood vessel development(GO:0060674) |
| 0.0 | 1.3 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.0 | 0.6 | GO:0031670 | cellular response to nutrient(GO:0031670) |
| 0.0 | 0.4 | GO:2000114 | regulation of establishment or maintenance of cell polarity(GO:0032878) regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.1 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.0 | 1.4 | GO:0007492 | endoderm development(GO:0007492) |
| 0.0 | 0.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.3 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.0 | 0.2 | GO:0051923 | sulfation(GO:0051923) |
| 0.0 | 1.5 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.4 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.3 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.0 | 0.3 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.0 | 1.2 | GO:0034502 | protein localization to chromosome(GO:0034502) |
| 0.0 | 0.1 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.0 | 0.1 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.1 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 0.4 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.1 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 2.4 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 0.0 | 0.2 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.3 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.6 | GO:0003170 | heart valve development(GO:0003170) |
| 0.0 | 0.2 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.0 | 0.1 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.4 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.2 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.1 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 0.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) positive regulation of thymocyte apoptotic process(GO:0070245) |
| 0.0 | 0.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.0 | 0.1 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.0 | 0.3 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 0.1 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.0 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.0 | 0.2 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.0 | 2.1 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.0 | 0.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.1 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 1.1 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 0.4 | GO:0042073 | intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840) |
| 0.0 | 0.1 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.0 | 0.1 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.0 | 18.0 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 3.9 | 11.6 | GO:0044194 | cytolytic granule(GO:0044194) |
| 3.5 | 14.0 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 1.7 | 5.1 | GO:0000802 | transverse filament(GO:0000802) |
| 1.5 | 7.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 1.4 | 9.7 | GO:0033263 | CORVET complex(GO:0033263) |
| 1.1 | 3.4 | GO:0000801 | central element(GO:0000801) |
| 1.1 | 9.6 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 1.0 | 5.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 1.0 | 5.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.0 | 6.7 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.9 | 7.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.9 | 2.7 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.8 | 2.4 | GO:0000798 | nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991) |
| 0.8 | 11.8 | GO:0043196 | varicosity(GO:0043196) |
| 0.8 | 5.3 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.8 | 5.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.7 | 2.2 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.7 | 2.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.7 | 2.9 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.7 | 2.8 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.7 | 2.0 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.7 | 5.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.6 | 5.7 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.6 | 2.3 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.6 | 1.7 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.5 | 3.8 | GO:0070695 | FHF complex(GO:0070695) |
| 0.5 | 1.5 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.5 | 3.5 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.5 | 5.9 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.5 | 4.1 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.5 | 2.3 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.4 | 2.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.4 | 2.2 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.4 | 3.4 | GO:0031415 | NatA complex(GO:0031415) |
| 0.4 | 1.7 | GO:1990795 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.4 | 3.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.4 | 3.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.4 | 1.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.4 | 2.3 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.4 | 5.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.4 | 2.8 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.3 | 3.7 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.3 | 2.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.3 | 2.0 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.3 | 6.0 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.3 | 4.8 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.3 | 0.6 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.3 | 1.2 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.3 | 2.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.3 | 8.2 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.3 | 1.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.3 | 1.6 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 4.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 2.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.2 | 0.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.2 | 1.6 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.2 | 1.4 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 3.1 | GO:0043203 | axon hillock(GO:0043203) |
| 0.2 | 3.0 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.2 | 15.1 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.2 | 1.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.2 | 3.1 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.2 | 60.8 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.2 | 0.6 | GO:0036501 | UFD1-NPL4 complex(GO:0036501) |
| 0.2 | 1.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 0.9 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.2 | 2.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.2 | 4.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.2 | 12.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.2 | 1.4 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.2 | 0.7 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.2 | 1.5 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.2 | 2.0 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.2 | 5.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.2 | 1.3 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.2 | 5.5 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.2 | 1.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.2 | 1.4 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 0.6 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 0.9 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.1 | 4.0 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 4.1 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 15.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 0.8 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 3.1 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 4.1 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 1.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 3.3 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.1 | 6.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 0.6 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 0.8 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 2.1 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 0.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 0.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.7 | GO:0042581 | specific granule(GO:0042581) |
| 0.1 | 6.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 0.6 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 5.6 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 0.3 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.1 | 1.5 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 0.4 | GO:0097361 | CIA complex(GO:0097361) |
| 0.1 | 0.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 0.2 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.1 | 3.1 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.1 | 0.6 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 7.2 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.3 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.1 | 0.8 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 2.9 | GO:0005770 | late endosome(GO:0005770) |
| 0.1 | 2.3 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 1.0 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 7.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 2.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 0.4 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.1 | 0.4 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.4 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 0.3 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.1 | 3.4 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 5.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 2.4 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.3 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 3.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.6 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 2.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 10.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 1.2 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 0.4 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 3.1 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.4 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.0 | 0.7 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.2 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 1.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 1.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 2.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 4.2 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.5 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 2.1 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.1 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.0 | 4.1 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.0 | 1.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 91.7 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.1 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
| 0.0 | 0.1 | GO:0005712 | chiasma(GO:0005712) |
| 0.0 | 0.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.8 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.0 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.0 | 0.0 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 0.7 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 2.9 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 0.4 | GO:0036126 | sperm flagellum(GO:0036126) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 16.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 2.6 | 15.8 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 2.5 | 58.5 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 1.9 | 5.7 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 1.6 | 4.7 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 1.4 | 4.3 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 1.3 | 5.3 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 1.2 | 6.0 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 1.1 | 5.7 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 1.1 | 5.6 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 1.0 | 3.1 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 1.0 | 6.2 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 1.0 | 8.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 1.0 | 6.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.9 | 2.8 | GO:0032450 | oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450) |
| 0.9 | 2.8 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.9 | 3.6 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.8 | 5.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 2.3 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
| 0.8 | 4.6 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.7 | 11.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.7 | 19.7 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.7 | 7.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.6 | 11.6 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.6 | 2.4 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.6 | 2.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.6 | 7.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.6 | 3.4 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.6 | 2.2 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.5 | 3.8 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.5 | 4.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.5 | 6.5 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
| 0.5 | 4.9 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.5 | 1.5 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.5 | 1.5 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.5 | 3.9 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.5 | 1.4 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.5 | 5.8 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.5 | 2.8 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.5 | 2.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 2.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.5 | 1.4 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.5 | 3.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.5 | 3.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.5 | 4.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.4 | 1.3 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.4 | 1.3 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.4 | 4.1 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
| 0.4 | 9.5 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.4 | 3.3 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.4 | 12.0 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.4 | 1.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.4 | 1.1 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.4 | 2.2 | GO:0009374 | biotin binding(GO:0009374) |
| 0.4 | 8.6 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.3 | 2.8 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
| 0.3 | 1.4 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.3 | 1.4 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.3 | 3.7 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.3 | 4.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.3 | 6.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.3 | 5.2 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.3 | 3.5 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.3 | 1.0 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.3 | 7.5 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.3 | 2.7 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.3 | 6.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.3 | 3.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 3.6 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.3 | 0.9 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.3 | 1.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 4.8 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.3 | 1.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.3 | 1.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.3 | 1.9 | GO:0032795 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
| 0.3 | 1.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.3 | 5.0 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.3 | 0.8 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.3 | 7.4 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.3 | 2.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.3 | 0.8 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.3 | 3.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.3 | 2.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.3 | 1.0 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.2 | 0.2 | GO:0019187 | beta-1,4-mannosyltransferase activity(GO:0019187) |
| 0.2 | 1.5 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.2 | 1.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.2 | 4.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 0.7 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
| 0.2 | 2.2 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.2 | 0.7 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.2 | 4.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.2 | 0.9 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.2 | 10.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 1.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 1.9 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.2 | 1.2 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.2 | 0.8 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
| 0.2 | 2.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.2 | 1.6 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.2 | 0.8 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.2 | 14.2 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.2 | 1.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.2 | 1.5 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.2 | 6.9 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.2 | 0.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 4.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.2 | 1.5 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.2 | 0.2 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.2 | 0.6 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.2 | 0.8 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.2 | 4.1 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 3.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 10.7 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 1.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.4 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 0.7 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.1 | 0.9 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.1 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.1 | 0.5 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 7.8 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.1 | 0.5 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.1 | 0.9 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.1 | 0.4 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.1 | 1.2 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 1.1 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.1 | 0.6 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 2.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.6 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.1 | 6.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 9.0 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.1 | 0.4 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.1 | 4.7 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.1 | 11.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 0.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 0.6 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.1 | 0.4 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.1 | 1.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.2 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.1 | 3.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.4 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 1.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.2 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 2.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.8 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 13.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.4 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 0.4 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 0.8 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
| 0.1 | 1.6 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 0.3 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.1 | 4.5 | GO:0004497 | monooxygenase activity(GO:0004497) |
| 0.1 | 0.2 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.1 | 4.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 3.5 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 11.8 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.1 | 1.6 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 0.6 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.1 | 0.2 | GO:0002094 | polyprenyltransferase activity(GO:0002094) |
| 0.1 | 0.9 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 1.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.5 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.4 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.1 | 0.3 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 0.6 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 0.2 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 3.9 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 0.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.1 | 2.9 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 1.3 | GO:0043492 | ATPase activity, coupled to movement of substances(GO:0043492) |
| 0.1 | 2.8 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 0.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.1 | 0.3 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 0.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 1.3 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 1.0 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 0.2 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.1 | 3.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.1 | 0.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 15.8 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 4.6 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 0.9 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 1.8 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 1.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 3.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.1 | 3.2 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.1 | 1.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 0.5 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
| 0.1 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.9 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
| 0.0 | 0.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 1.7 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.0 | 0.2 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.0 | 0.3 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.6 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.3 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.0 | 0.7 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.0 | 0.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 0.1 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.0 | 1.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.6 | GO:0050253 | prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
| 0.0 | 0.3 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 0.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
| 0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.0 | 9.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.2 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) |
| 0.0 | 0.1 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.1 | GO:0019002 | GMP binding(GO:0019002) |
| 0.0 | 1.0 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 2.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.4 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 0.2 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.0 | 0.2 | GO:0034946 | 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466) |
| 0.0 | 2.7 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.4 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.4 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.2 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.0 | 2.0 | GO:0015929 | hexosaminidase activity(GO:0015929) |
| 0.0 | 0.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 3.9 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.4 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.9 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.0 | 0.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.7 | GO:0045502 | dynein binding(GO:0045502) |
| 0.0 | 1.3 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.2 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 5.4 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.0 | 0.3 | GO:0008758 | thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606) |
| 0.0 | 0.6 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.1 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.0 | 0.0 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.0 | 0.1 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.2 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.0 | 0.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.3 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.0 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.2 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.0 | 0.1 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 0.1 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
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