Motif ID: Thra

Z-value: 0.771


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98741805_98741816-0.818.6e-15Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_84839833 7.554 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chrX_-_143827391 6.749 ENSMUST00000087316.5
Capn6
calpain 6
chr11_+_69965396 6.441 ENSMUST00000018713.6
Cldn7
claudin 7
chr4_+_44300876 6.219 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr5_-_116422858 5.608 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr7_-_141214080 5.434 ENSMUST00000026573.5
ENSMUST00000170841.1
1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr18_+_57142782 5.397 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr13_+_44729794 5.339 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr13_+_94875600 5.083 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr12_+_79029150 4.713 ENSMUST00000039928.5
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr17_+_85620816 4.666 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr14_-_118706180 4.455 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr4_-_137766474 3.851 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr1_-_84839304 3.717 ENSMUST00000027421.6
Trip12
thyroid hormone receptor interactor 12
chr12_+_112678803 3.630 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
Zbtb42


zinc finger and BTB domain containing 42


chr1_-_163994767 3.612 ENSMUST00000097493.3
ENSMUST00000045876.6
BC055324

cDNA sequence BC055324

chr6_+_83137089 3.430 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr5_-_134946917 3.365 ENSMUST00000051401.2
Cldn4
claudin 4
chr6_+_113531675 3.324 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr1_+_131910458 3.321 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.1 GO:0051028 mRNA transport(GO:0051028)
0.8 7.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 7.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 6.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.5 6.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 6.2 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
1.5 6.0 GO:0098763 mitotic cell cycle phase(GO:0098763)
1.1 5.4 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.4 5.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
1.6 4.7 GO:0097402 neuroblast migration(GO:0097402)
0.5 4.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 4.4 GO:0043297 apical junction assembly(GO:0043297)
0.0 4.0 GO:0060348 bone development(GO:0060348)
0.4 3.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 3.9 GO:0046677 response to antibiotic(GO:0046677)
0.3 3.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.2 3.7 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.4 3.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.5 3.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.5 3.3 GO:0007296 vitellogenesis(GO:0007296)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 9.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 7.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 6.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 6.2 GO:0000776 kinetochore(GO:0000776)
0.5 5.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 5.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 4.7 GO:0005902 microvillus(GO:0005902)
1.5 4.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)
0.2 3.9 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 3.6 GO:0005643 nuclear pore(GO:0005643)
0.0 3.3 GO:0000793 condensed chromosome(GO:0000793)
0.6 3.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 3.0 GO:0032420 stereocilium(GO:0032420)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 2.9 GO:0005840 ribosome(GO:0005840)
0.1 2.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 2.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.0 2.6 GO:0016234 inclusion body(GO:0016234)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 7.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 7.7 GO:0032452 histone demethylase activity(GO:0032452)
0.4 6.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 6.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 5.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 5.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 5.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 4.7 GO:0001222 transcription corepressor binding(GO:0001222)
1.0 3.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.5 3.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 3.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 3.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 3.2 GO:0003774 motor activity(GO:0003774)
0.5 3.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 3.1 GO:0043495 protein anchor(GO:0043495)
0.4 3.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 3.0 GO:0051087 chaperone binding(GO:0051087)
0.1 2.8 GO:0005184 neuropeptide hormone activity(GO:0005184)