Motif ID: Tlx1

Z-value: 1.043


Transcription factors associated with Tlx1:

Gene SymbolEntrez IDGene Name
Tlx1 ENSMUSG00000025215.9 Tlx1



Activity profile for motif Tlx1.

activity profile for motif Tlx1


Sorted Z-values histogram for motif Tlx1

Sorted Z-values for motif Tlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_43730593 12.976 ENSMUST00000027217.8
 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr7_-_97417730 10.563 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr1_+_185454803 10.205 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr7_+_130936172 9.801 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr2_-_25470031 9.725 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr6_-_115251839 9.520 ENSMUST00000032462.6
 Timp4
tissue inhibitor of metalloproteinase 4
chr18_-_78206408 9.200 ENSMUST00000163367.1
 Slc14a2
solute carrier family 14 (urea transporter), member 2
chr6_+_54681687 9.091 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr16_+_90831113 8.805 ENSMUST00000037539.7
ENSMUST00000099543.3
 Eva1c

eva-1 homolog C (C. elegans)

chr6_+_135362931 8.798 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr4_+_48045144 8.724 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr6_+_55452177 7.935 ENSMUST00000167484.1
 Adcyap1r1
adenylate cyclase activating polypeptide 1 receptor 1
chr6_+_55451978 7.555 ENSMUST00000070736.5
ENSMUST00000070756.5
ENSMUST00000166962.1
 Adcyap1r1


adenylate cyclase activating polypeptide 1 receptor 1


chr12_+_95692212 7.528 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_+_172341197 7.214 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr1_-_56969864 7.161 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr12_-_78983476 7.065 ENSMUST00000070174.7
 Tmem229b
transmembrane protein 229B
chr8_-_109251698 6.900 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr2_-_164404606 6.737 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
 Matn4


matrilin 4


chr5_+_16553488 6.537 ENSMUST00000030683.3
 Hgf
hepatocyte growth factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.0 24.2 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
1.3 15.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
2.2 15.3 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
2.9 14.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.6 13.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 10.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
1.1 10.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 10.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
1.6 9.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.9 9.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.2 9.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 8.8 GO:0032060 bleb assembly(GO:0032060)
2.9 8.7 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 8.2 GO:0007018 microtubule-based movement(GO:0007018)
1.3 7.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
2.4 7.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.4 7.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 6.7 GO:0048678 response to axon injury(GO:0048678)
1.3 6.5 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
1.6 6.2 GO:0019372 lipoxygenase pathway(GO:0019372)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 28.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
3.5 24.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.0 15.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 9.7 GO:0030017 sarcomere(GO:0030017)
0.1 9.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 8.3 GO:0005871 kinesin complex(GO:0005871)
0.1 7.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.6 7.2 GO:0097449 astrocyte projection(GO:0097449)
2.1 6.3 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 6.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 6.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 5.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.8 GO:0055037 recycling endosome(GO:0055037)
0.0 4.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.9 4.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 4.5 GO:0000139 Golgi membrane(GO:0000139)
0.2 4.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 4.1 GO:0032589 neuron projection membrane(GO:0032589)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 24.2 GO:0051787 misfolded protein binding(GO:0051787)
3.9 15.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.5 15.3 GO:0015265 urea channel activity(GO:0015265)
1.1 14.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 12.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
2.4 9.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 9.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 9.2 GO:0003777 microtubule motor activity(GO:0003777)
0.5 8.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 8.4 GO:0042056 chemoattractant activity(GO:0042056)
1.0 7.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 7.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 7.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
2.4 7.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 6.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.2 6.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.4 5.8 GO:0004096 catalase activity(GO:0004096)
0.5 5.6 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.9 5.4 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
1.3 5.1 GO:0097642 calcitonin family receptor activity(GO:0097642)