Motif ID: Vdr
Z-value: 0.957
Transcription factors associated with Vdr:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Vdr | ENSMUSG00000022479.9 | Vdr |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.9 | 11.4 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
2.3 | 9.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
1.6 | 9.6 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
1.6 | 6.2 | GO:0006867 | asparagine transport(GO:0006867) glutamine transport(GO:0006868) |
1.2 | 3.7 | GO:1904049 | regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
1.1 | 4.5 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
1.1 | 7.8 | GO:0071361 | cellular response to ethanol(GO:0071361) |
1.1 | 3.2 | GO:0035934 | corticosterone secretion(GO:0035934) |
0.9 | 2.8 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.9 | 4.3 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
0.8 | 5.1 | GO:1903352 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
0.8 | 2.4 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.7 | 4.9 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.7 | 7.0 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.5 | 1.6 | GO:0006533 | aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478) |
0.5 | 9.3 | GO:0060134 | prepulse inhibition(GO:0060134) |
0.4 | 2.9 | GO:0002591 | positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) |
0.4 | 1.9 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
0.4 | 1.1 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.3 | 3.0 | GO:0031424 | keratinization(GO:0031424) |
0.3 | 2.2 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
0.3 | 0.9 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
0.3 | 1.2 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.3 | 5.2 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.3 | 0.9 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.3 | 0.9 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.3 | 0.6 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
0.3 | 0.8 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.2 | 0.7 | GO:0031117 | serotonin receptor signaling pathway(GO:0007210) positive regulation of microtubule depolymerization(GO:0031117) |
0.2 | 1.7 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
0.2 | 2.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.2 | 1.9 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.2 | 0.8 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.2 | 0.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.2 | 2.3 | GO:0090051 | angiogenesis involved in wound healing(GO:0060055) negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
0.1 | 0.4 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
0.1 | 0.4 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.1 | 0.8 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
0.1 | 0.9 | GO:0003062 | regulation of heart rate by chemical signal(GO:0003062) |
0.1 | 1.4 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
0.1 | 1.2 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.1 | 5.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.1 | 0.7 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.1 | 8.1 | GO:0021766 | hippocampus development(GO:0021766) |
0.1 | 2.2 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
0.1 | 1.6 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 0.3 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
0.1 | 0.8 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 0.4 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.1 | 0.8 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.1 | 0.6 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 2.2 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.1 | 0.2 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.1 | 0.4 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
0.1 | 1.5 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
0.1 | 1.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.1 | 0.3 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
0.0 | 1.0 | GO:0033622 | integrin activation(GO:0033622) |
0.0 | 2.2 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.1 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.0 | 2.3 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 2.7 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.0 | 2.2 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 0.9 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.4 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.4 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.8 | GO:0006986 | response to unfolded protein(GO:0006986) |
0.0 | 0.6 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.2 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 0.4 | GO:0030168 | platelet activation(GO:0030168) |
0.0 | 2.0 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.0 | 0.1 | GO:1901896 | Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068) positive regulation of calcium-transporting ATPase activity(GO:1901896) |
0.0 | 0.7 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.0 | 2.3 | GO:0098780 | mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780) |
0.0 | 1.0 | GO:0043062 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
0.0 | 0.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.7 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.0 | 0.2 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.0 | 0.5 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 11.4 | GO:0031983 | vesicle lumen(GO:0031983) |
0.8 | 3.0 | GO:0001533 | cornified envelope(GO:0001533) |
0.5 | 2.7 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.5 | 3.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.4 | 7.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.2 | 2.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 1.9 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 2.0 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 4.7 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 0.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.1 | 0.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 6.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 9.2 | GO:0005814 | centriole(GO:0005814) |
0.1 | 11.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.1 | 2.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.1 | 0.2 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
0.1 | 0.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 0.4 | GO:0070820 | tertiary granule(GO:0070820) |
0.1 | 0.6 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 0.8 | GO:0030056 | hemidesmosome(GO:0030056) |
0.1 | 0.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 0.7 | GO:0043203 | axon hillock(GO:0043203) |
0.1 | 0.4 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.9 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.2 | GO:0036157 | outer dynein arm(GO:0036157) |
0.0 | 8.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 2.3 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.9 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 3.5 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 2.9 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 2.0 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 1.8 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 5.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 5.3 | GO:0005911 | cell-cell junction(GO:0005911) |
0.0 | 0.4 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.3 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.0 | 0.8 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 5.5 | GO:0005794 | Golgi apparatus(GO:0005794) |
0.0 | 0.4 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.6 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 0.8 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 1.2 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 11.4 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
2.6 | 7.8 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
1.4 | 7.0 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
1.2 | 6.2 | GO:0015186 | L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186) |
0.9 | 4.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.7 | 5.1 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
0.7 | 2.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.7 | 4.0 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.6 | 2.9 | GO:0015440 | peptide-transporting ATPase activity(GO:0015440) |
0.6 | 4.5 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.5 | 1.5 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
0.5 | 9.1 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.4 | 4.9 | GO:0038191 | neuropilin binding(GO:0038191) |
0.4 | 1.6 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922) |
0.4 | 1.4 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
0.4 | 3.5 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
0.3 | 0.9 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.3 | 0.9 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.3 | 0.8 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.2 | 0.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) |
0.2 | 1.3 | GO:0016936 | galactoside binding(GO:0016936) |
0.2 | 9.3 | GO:0005504 | fatty acid binding(GO:0005504) |
0.2 | 0.7 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589) |
0.2 | 1.9 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.2 | 7.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 1.3 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 2.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.1 | 2.4 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.1 | 0.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 3.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.5 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.1 | 1.6 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.1 | 0.4 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.1 | 2.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) |
0.1 | 4.2 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.1 | 0.8 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 0.8 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
0.1 | 3.3 | GO:0050699 | WW domain binding(GO:0050699) |
0.1 | 1.2 | GO:0019215 | phosphatidylinositol-3-phosphatase activity(GO:0004438) intermediate filament binding(GO:0019215) |
0.1 | 0.2 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
0.1 | 2.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 1.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 0.4 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.1 | 2.4 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 3.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.6 | GO:0046933 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.3 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 0.4 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.0 | 1.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 1.1 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 1.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.5 | GO:0042556 | cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
0.0 | 1.0 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.3 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.0 | 0.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 5.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.1 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763) |
0.0 | 0.3 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.0 | 1.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |