Motif ID: Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 0.992


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Uncxmm10_v2_chr5_+_139543889_1395439040.581.7e-06Click!
Prrx2mm10_v2_chr2_+_30834972_308349720.462.5e-04Click!
Shox2mm10_v2_chr3_-_66981279_669813180.364.7e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48665098 40.273 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr5_+_139543889 25.787 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_-_168767136 22.552 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr13_-_53473074 21.050 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr2_-_168767029 20.978 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr3_+_159839729 20.610 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr17_+_34592248 19.940 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr7_-_49636847 17.458 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr8_-_61902669 16.249 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr10_-_45470201 16.232 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr13_-_102905740 14.127 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_125404072 12.946 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_-_102906046 12.791 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_125404292 12.583 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_55782500 11.455 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr3_-_154328634 11.102 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr6_-_147264124 10.704 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr9_+_119063429 10.588 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr2_-_72986716 10.278 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr9_+_72806874 9.645 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr7_-_37773555 9.563 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr13_+_89540636 8.627 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr3_+_134236483 7.846 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr16_-_26989974 7.813 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr3_-_88410295 7.653 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr2_+_109917639 7.589 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr14_-_46390501 7.557 ENSMUST00000100676.2
Bmp4
bone morphogenetic protein 4
chr14_-_118052235 7.478 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr7_-_116198487 7.107 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr3_+_122419772 6.957 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr14_-_46390576 6.627 ENSMUST00000074077.5
Bmp4
bone morphogenetic protein 4
chr3_-_86548268 6.519 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chrX_-_139871637 6.512 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr19_+_59458372 6.491 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr17_+_17402672 6.406 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr3_-_49757257 6.330 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr2_-_28916412 6.211 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr4_-_35845204 6.132 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr3_+_122044428 6.069 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr15_+_25773985 5.970 ENSMUST00000125667.1
Myo10
myosin X
chr6_+_29859374 5.490 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr6_+_29859662 5.269 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr4_+_136143497 5.266 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr6_-_124779686 5.165 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr5_+_15516489 5.134 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr2_+_25372315 5.056 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr2_-_33718789 5.020 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr3_-_17786834 4.909 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr6_+_125552948 4.885 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr6_+_29859686 4.844 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr7_+_49910112 4.843 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr4_-_58499398 4.809 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr7_+_144838590 4.759 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr11_-_50292302 4.746 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr2_-_28916668 4.713 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr11_+_60537978 4.693 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr2_+_20737306 4.532 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr8_-_120228221 4.525 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr7_-_45830776 4.509 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr5_-_62765618 4.442 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_+_150547375 4.394 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chrM_+_7005 4.353 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr2_+_152754156 4.344 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr18_+_56432116 4.294 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr5_+_115235836 4.213 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr13_+_44121167 4.170 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr12_+_38780284 4.077 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr9_+_96258697 4.070 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chrX_-_60893430 4.067 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr7_+_125829653 4.059 ENSMUST00000124223.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr3_-_79841729 4.023 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr7_-_37772868 3.995 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr3_-_100489324 3.966 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr7_-_115824699 3.917 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr14_-_48667508 3.884 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr7_-_66427469 3.806 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr12_-_57546121 3.778 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr2_+_9882622 3.720 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene
chrX_-_74246534 3.706 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr4_-_97778042 3.698 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_+_102604370 3.565 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr2_-_18048784 3.540 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr13_+_8202885 3.523 ENSMUST00000139438.1
ENSMUST00000135574.1
Adarb2

adenosine deaminase, RNA-specific, B2

chr13_-_114458720 3.522 ENSMUST00000022287.5
Fst
follistatin
chr2_-_58052832 3.518 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr1_-_163725123 3.501 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr14_+_79515618 3.484 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr11_+_114851507 3.474 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr18_+_4993795 3.459 ENSMUST00000153016.1
Svil
supervillin
chr10_+_128337761 3.423 ENSMUST00000005826.7
Cs
citrate synthase
chr6_-_148946146 3.342 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr1_-_72284248 3.326 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr5_+_138187485 3.248 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr17_-_35697971 3.242 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr12_+_38780817 3.240 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr18_-_66022580 3.190 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr9_+_106368594 3.158 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr1_+_109983737 3.097 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr10_+_99263224 3.094 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr11_+_94327984 3.080 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr5_+_135106881 3.069 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr10_+_26772477 2.986 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr2_-_147186389 2.967 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr2_-_30093642 2.828 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_+_52098681 2.811 ENSMUST00000020608.2
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr2_+_3114220 2.811 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr19_+_24875679 2.807 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr13_-_78196373 2.765 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr1_+_153665666 2.760 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr15_-_9140374 2.760 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr13_+_51408618 2.721 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chrX_+_56454871 2.710 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr6_+_15196949 2.661 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr1_+_153665274 2.585 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr1_-_190170178 2.583 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr1_+_153665587 2.515 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chrX_+_159303266 2.504 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr1_-_190170671 2.462 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr7_+_28881656 2.434 ENSMUST00000066880.4
Capn12
calpain 12
chr7_+_114745685 2.412 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr15_-_13173607 2.322 ENSMUST00000036439.4
Cdh6
cadherin 6
chr12_+_38781093 2.315 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr10_+_88091070 2.308 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chrX_-_102157065 2.299 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr2_+_132847719 2.283 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr1_+_10993452 2.272 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr11_-_31671863 2.249 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr1_+_153665627 2.228 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr3_-_157925056 2.179 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr2_+_52038005 2.173 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr6_+_29853746 2.172 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr8_+_121116163 2.165 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr11_+_98798653 2.157 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr3_+_121291725 2.132 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr3_+_32515295 2.102 ENSMUST00000029203.7
Zfp639
zinc finger protein 639
chr18_+_34758890 2.045 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr10_+_102158858 2.033 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr2_-_27475622 1.986 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
Brd3


bromodomain containing 3


chr2_-_30093607 1.970 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr5_-_138187177 1.927 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr19_+_55895508 1.922 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr6_-_148831448 1.911 ENSMUST00000048418.7
Ipo8
importin 8
chrM_+_2743 1.905 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr2_+_71389239 1.892 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr15_-_79285502 1.878 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr18_+_61639542 1.798 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr1_-_78968079 1.781 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr12_+_38783455 1.774 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr13_+_75707484 1.748 ENSMUST00000001583.6
Ell2
elongation factor RNA polymerase II 2
chr4_+_150853919 1.736 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr12_-_40037387 1.734 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chrX_+_150589907 1.730 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_+_80638798 1.719 ENSMUST00000028382.6
ENSMUST00000124377.1
Nup35

nucleoporin 35

chr14_+_73237891 1.705 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr1_-_172027269 1.702 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr9_+_65890237 1.691 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr14_+_53324632 1.683 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr11_-_31671727 1.677 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr5_-_87482258 1.652 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr5_-_138170992 1.648 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_-_50890041 1.627 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_5014645 1.595 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr18_+_54990280 1.571 ENSMUST00000181538.1
Gm4221
predicted gene 4221
chr5_-_138171248 1.566 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_-_59170978 1.549 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr13_-_97747373 1.544 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_132510493 1.529 ENSMUST00000030724.8
Sesn2
sestrin 2
chr10_+_128747850 1.529 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chrX_+_169685191 1.507 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr8_-_45382198 1.506 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr6_+_37870786 1.492 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr15_-_102350692 1.477 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr19_-_15924560 1.472 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr12_-_111813834 1.407 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr9_-_71163224 1.405 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr7_-_37769624 1.401 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr4_+_99955715 1.378 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr2_+_38341068 1.371 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr17_+_45734506 1.370 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr1_+_137928100 1.357 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr15_-_34495180 1.329 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chr17_+_12119274 1.314 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr4_+_154960915 1.307 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr10_-_53647080 1.279 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr11_-_3931789 1.275 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr6_+_7555053 1.263 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr15_+_81744848 1.231 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr8_+_23411490 1.204 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr4_-_42168603 1.183 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr6_-_148831395 1.176 ENSMUST00000145960.1
Ipo8
importin 8
chr4_+_8690399 1.153 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr11_-_3931960 1.147 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr18_+_24603952 1.142 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr10_+_37139558 1.140 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr7_+_131542867 1.128 ENSMUST00000046093.5
Hmx3
H6 homeobox 3
chr9_+_45138437 1.110 ENSMUST00000060125.5
Scn4b
sodium channel, type IV, beta
chr17_-_24073479 1.088 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr1_-_165934900 1.081 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr13_-_81570640 1.080 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr10_-_80421847 1.076 ENSMUST00000156244.1
Tcf3
transcription factor 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 44.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
7.0 21.0 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
4.7 14.2 GO:0048389 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) intermediate mesoderm development(GO:0048389) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) pattern specification involved in mesonephros development(GO:0061227) regulation of hepatocyte differentiation(GO:0070366) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior/posterior pattern specification involved in kidney development(GO:0072098) negative regulation of glomerular mesangial cell proliferation(GO:0072125) ureter urothelium development(GO:0072190) negative regulation of glomerulus development(GO:0090194) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.2 25.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
2.5 7.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
2.4 43.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
2.2 17.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.9 3.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.9 7.5 GO:0021847 ventricular zone neuroblast division(GO:0021847)
1.8 10.9 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
1.8 16.2 GO:0010587 miRNA catabolic process(GO:0010587)
1.7 5.0 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
1.6 4.8 GO:0030916 otic vesicle formation(GO:0030916)
1.6 20.6 GO:0031017 exocrine pancreas development(GO:0031017)
1.6 4.7 GO:0003162 atrioventricular node development(GO:0003162)
1.5 3.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.3 3.8 GO:0060166 olfactory pit development(GO:0060166)
1.2 4.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.2 7.1 GO:0045218 zonula adherens maintenance(GO:0045218)
1.2 3.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
1.2 4.7 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
1.1 17.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.1 16.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.0 3.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.0 3.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.0 3.9 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.9 15.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.9 4.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.9 1.7 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.8 2.4 GO:0015889 cobalamin transport(GO:0015889)
0.8 4.8 GO:0036233 glycine import(GO:0036233)
0.8 10.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.8 2.3 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.7 2.2 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.7 4.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.7 2.2 GO:0072071 apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.7 3.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.7 4.2 GO:0009249 protein lipoylation(GO:0009249)
0.7 1.3 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.6 1.9 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.6 1.2 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.5 0.5 GO:0061743 motor learning(GO:0061743)
0.5 1.5 GO:0090526 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 12.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 2.8 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.4 11.6 GO:0006270 DNA replication initiation(GO:0006270)
0.4 1.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) ventricular compact myocardium morphogenesis(GO:0003223)
0.4 1.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.4 1.9 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.4 2.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.4 6.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 1.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139)
0.3 2.8 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.3 5.7 GO:0021542 dentate gyrus development(GO:0021542)
0.3 8.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 2.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 1.0 GO:0043586 tongue development(GO:0043586)
0.3 0.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.3 0.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 2.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.3 2.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 3.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 1.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.7 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 4.1 GO:0007530 sex determination(GO:0007530)
0.3 1.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.9 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 1.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 6.4 GO:0097352 autophagosome maturation(GO:0097352)
0.2 1.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 5.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 3.3 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 2.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 0.7 GO:0050748 negative regulation of receptor biosynthetic process(GO:0010871) negative regulation of lipoprotein metabolic process(GO:0050748)
0.2 3.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 0.9 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 11.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.2 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.2 1.5 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 10.6 GO:0051693 actin filament capping(GO:0051693)
0.2 0.7 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 3.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.6 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.2 1.9 GO:0051764 actin crosslink formation(GO:0051764)
0.2 1.0 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 1.2 GO:0060539 diaphragm development(GO:0060539)
0.2 1.4 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.2 5.6 GO:0018345 protein palmitoylation(GO:0018345)
0.2 0.4 GO:1903977 positive regulation of Schwann cell migration(GO:1900149) positive regulation of glial cell migration(GO:1903977)
0.2 3.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.0 GO:0016078 tRNA catabolic process(GO:0016078)
0.2 0.3 GO:0060023 soft palate development(GO:0060023)
0.2 1.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 1.0 GO:0021756 striatum development(GO:0021756)
0.2 0.8 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 3.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 5.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.7 GO:0019985 translesion synthesis(GO:0019985)
0.1 3.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 3.6 GO:0030901 midbrain development(GO:0030901)
0.1 0.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032) hair follicle placode formation(GO:0060789)
0.1 1.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 3.5 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.9 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 1.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 1.0 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 1.7 GO:0006999 nuclear pore organization(GO:0006999)
0.1 1.1 GO:0099625 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 3.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 1.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.6 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 5.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.7 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 1.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 7.8 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 0.2 GO:2000822 regulation of fear response(GO:1903365) positive regulation of fear response(GO:1903367) regulation of behavioral fear response(GO:2000822) positive regulation of behavioral fear response(GO:2000987)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphate ion transmembrane transport(GO:0035435)
0.1 0.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 4.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.4 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 2.5 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.7 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 0.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 2.7 GO:0030168 platelet activation(GO:0030168)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 2.6 GO:0007601 visual perception(GO:0007601)
0.0 0.9 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 2.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0032225 regulation of synaptic transmission, dopaminergic(GO:0032225)
0.0 1.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.6 GO:0006101 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.0 9.7 GO:0007067 mitotic nuclear division(GO:0007067)
0.0 2.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 3.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 6.7 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.9 GO:0071383 cellular response to steroid hormone stimulus(GO:0071383)
0.0 2.3 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 1.0 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.3 GO:0000154 rRNA modification(GO:0000154)
0.0 0.3 GO:0032922 circadian regulation of gene expression(GO:0032922)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.1 GO:0001674 female germ cell nucleus(GO:0001674)
1.8 5.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.3 7.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.0 4.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.9 4.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.9 4.4 GO:0031523 Myb complex(GO:0031523)
0.6 16.2 GO:0002102 podosome(GO:0002102)
0.6 7.1 GO:0005915 zonula adherens(GO:0005915)
0.6 20.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.6 1.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.5 4.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.5 0.5 GO:0044301 climbing fiber(GO:0044301)
0.4 3.5 GO:0033269 internode region of axon(GO:0033269)
0.4 2.2 GO:0072487 MSL complex(GO:0072487)
0.4 1.9 GO:0070826 paraferritin complex(GO:0070826)
0.4 1.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 43.4 GO:0000792 heterochromatin(GO:0000792)
0.3 7.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 1.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 9.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 3.8 GO:0042555 MCM complex(GO:0042555)
0.2 0.7 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.2 1.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 3.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.2 1.9 GO:0071439 clathrin complex(GO:0071439)
0.2 3.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.5 GO:0061700 GATOR2 complex(GO:0061700)
0.1 49.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.1 6.0 GO:0016459 myosin complex(GO:0016459)
0.1 5.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 21.0 GO:0030427 site of polarized growth(GO:0030427)
0.1 0.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 4.4 GO:0005902 microvillus(GO:0005902)
0.1 0.7 GO:0000124 SAGA complex(GO:0000124)
0.1 2.6 GO:0043034 costamere(GO:0043034)
0.1 1.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 4.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.9 GO:0045120 pronucleus(GO:0045120)
0.1 4.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 6.2 GO:0000776 kinetochore(GO:0000776)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 5.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.4 GO:0070469 respiratory chain(GO:0070469)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 7.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0000178 cytoplasmic exosome (RNase complex)(GO:0000177) exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 2.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 15.1 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.3 GO:0045177 apical part of cell(GO:0045177)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 13.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.6 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 23.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.6 25.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
2.5 17.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.8 5.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.6 14.2 GO:0039706 co-receptor binding(GO:0039706)
1.5 4.4 GO:0005118 sevenless binding(GO:0005118)
1.2 17.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.2 4.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
1.1 3.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.0 9.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.8 4.8 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.8 4.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.8 3.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.6 5.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.6 7.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.6 5.0 GO:0050693 LBD domain binding(GO:0050693)
0.6 10.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 7.1 GO:0070097 delta-catenin binding(GO:0070097)
0.6 7.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 3.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.5 1.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 7.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5 2.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.4 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 9.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.4 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 1.9 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 3.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 4.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 2.4 GO:0031419 cobalamin binding(GO:0031419)
0.3 2.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 11.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 3.5 GO:0048185 activin binding(GO:0048185)
0.3 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 2.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 5.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 2.8 GO:1990405 protein antigen binding(GO:1990405)
0.3 1.5 GO:0070728 leucine binding(GO:0070728)
0.2 1.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.7 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 1.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 1.4 GO:0015265 urea channel activity(GO:0015265)
0.2 3.2 GO:0005537 mannose binding(GO:0005537)
0.2 5.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2 4.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.5 GO:0034056 estrogen response element binding(GO:0034056)
0.2 4.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 67.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 4.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 31.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 4.7 GO:0042605 peptide antigen binding(GO:0042605)
0.2 6.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 101.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 26.2 GO:0000287 magnesium ion binding(GO:0000287)
0.1 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 3.7 GO:0016749 N-succinyltransferase activity(GO:0016749)
0.1 0.9 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 3.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.1 GO:0051378 serotonin binding(GO:0051378)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 4.4 GO:0030507 spectrin binding(GO:0030507)
0.1 3.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.5 GO:0008483 transaminase activity(GO:0008483)
0.1 24.7 GO:0003779 actin binding(GO:0003779)
0.1 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.6 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 1.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 5.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 2.8 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 8.6 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.1 GO:0004386 helicase activity(GO:0004386)
0.0 4.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 3.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0 9.6 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)