Motif ID: Wrnip1_Mta3_Rcor1

Z-value: 3.547

Transcription factors associated with Wrnip1_Mta3_Rcor1:

Gene SymbolEntrez IDGene Name
Mta3 ENSMUSG00000055817.11 Mta3
Rcor1 ENSMUSG00000037896.11 Rcor1
Wrnip1 ENSMUSG00000021400.6 Wrnip1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rcor1mm10_v2_chr12_+_111039334_111039400-0.462.3e-04Click!
Mta3mm10_v2_chr17_+_83706170_837062000.229.3e-02Click!
Wrnip1mm10_v2_chr13_+_32802007_328021520.162.4e-01Click!


Activity profile for motif Wrnip1_Mta3_Rcor1.

activity profile for motif Wrnip1_Mta3_Rcor1


Sorted Z-values histogram for motif Wrnip1_Mta3_Rcor1

Sorted Z-values for motif Wrnip1_Mta3_Rcor1



Network of associatons between targets according to the STRING database.



First level regulatory network of Wrnip1_Mta3_Rcor1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_120202104 24.128 ENSMUST00000033198.5
 Crym
crystallin, mu
chrX_+_73483602 15.273 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr7_-_142657466 14.977 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr7_+_45699843 13.770 ENSMUST00000003360.7
 Car11
carbonic anhydrase 11
chr14_-_29721835 13.766 ENSMUST00000022567.7
 Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr2_+_90885860 12.723 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr13_-_71963713 12.719 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr2_+_145167706 12.396 ENSMUST00000110007.1
 Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr11_+_101246405 12.073 ENSMUST00000122006.1
ENSMUST00000151830.1
 Ramp2

receptor (calcitonin) activity modifying protein 2

chr19_-_42431778 11.828 ENSMUST00000048630.6
 Crtac1
cartilage acidic protein 1
chr2_+_180499893 11.757 ENSMUST00000029084.2
 Ntsr1
neurotensin receptor 1
chr14_-_102982630 11.463 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr4_+_138454305 11.128 ENSMUST00000050918.3
 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr3_-_66981279 11.121 ENSMUST00000162098.2
 Shox2
short stature homeobox 2
chr5_-_108549934 10.913 ENSMUST00000129040.1
ENSMUST00000046892.9
 Cplx1

complexin 1

chr7_+_44428938 10.627 ENSMUST00000127790.1
 Lrrc4b
leucine rich repeat containing 4B
chr11_+_94936224 10.550 ENSMUST00000001547.7
 Col1a1
collagen, type I, alpha 1
chr9_+_44043384 10.547 ENSMUST00000114840.1
 Thy1
thymus cell antigen 1, theta
chr7_-_45103747 10.502 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr6_+_99692679 10.408 ENSMUST00000101122.1
 Gpr27
G protein-coupled receptor 27

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,462 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 54.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
1.7 53.2 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.8 46.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.5 43.8 GO:0007616 long-term memory(GO:0007616)
1.6 41.2 GO:0071625 vocalization behavior(GO:0071625)
1.2 40.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
1.1 39.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.7 35.6 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
3.9 35.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
6.9 34.3 GO:0070327 thyroid hormone transport(GO:0070327)
4.1 32.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.8 32.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.8 31.2 GO:0010507 negative regulation of autophagy(GO:0010507)
3.2 28.6 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
1.4 28.4 GO:0035640 exploration behavior(GO:0035640)
1.2 27.1 GO:0048268 clathrin coat assembly(GO:0048268)
3.0 26.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.2 25.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
4.2 25.3 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.6 25.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 397 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1304.8 GO:0016021 integral component of membrane(GO:0016021)
0.6 178.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.9 168.2 GO:0045211 postsynaptic membrane(GO:0045211)
1.0 164.7 GO:0070382 exocytic vesicle(GO:0070382)
0.9 160.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 116.6 GO:0005615 extracellular space(GO:0005615)
1.5 91.1 GO:0042734 presynaptic membrane(GO:0042734)
0.1 87.6 GO:0005576 extracellular region(GO:0005576)
1.5 87.4 GO:0005581 collagen trimer(GO:0005581)
1.8 75.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.8 72.2 GO:0031225 anchored component of membrane(GO:0031225)
0.7 67.4 GO:0055037 recycling endosome(GO:0055037)
1.6 66.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.1 62.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
1.1 54.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.5 41.8 GO:0033268 node of Ranvier(GO:0033268)
0.9 41.0 GO:0043195 terminal bouton(GO:0043195)
0.8 40.2 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
1.5 38.0 GO:0032590 dendrite membrane(GO:0032590)
0.5 35.6 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 769 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 109.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 75.5 GO:0005509 calcium ion binding(GO:0005509)
1.3 58.5 GO:0050840 extracellular matrix binding(GO:0050840)
1.5 56.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
2.4 56.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.5 55.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.8 52.3 GO:0016247 channel regulator activity(GO:0016247)
0.6 49.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
3.2 48.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.3 47.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 42.9 GO:0003924 GTPase activity(GO:0003924)
1.3 42.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
5.1 40.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 40.0 GO:0017124 SH3 domain binding(GO:0017124)
1.2 38.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 37.7 GO:0008289 lipid binding(GO:0008289)
0.5 37.0 GO:0005125 cytokine activity(GO:0005125)
0.9 36.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.7 36.3 GO:0030507 spectrin binding(GO:0030507)
1.5 35.6 GO:0017075 syntaxin-1 binding(GO:0017075)