Motif ID: Xbp1_Creb3l1
Z-value: 0.828
Transcription factors associated with Xbp1_Creb3l1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Creb3l1 | ENSMUSG00000027230.9 | Creb3l1 |
| Xbp1 | ENSMUSG00000020484.12 | Xbp1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Creb3l1 | mm10_v2_chr2_-_92024502_92024529 | 0.42 | 7.9e-04 | Click! |
| Xbp1 | mm10_v2_chr11_+_5520652_5520659 | -0.14 | 3.0e-01 | Click! |
Top targets:
Showing 1 to 20 of 169 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 64 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 7.0 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.4 | 6.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.5 | 5.0 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.3 | 4.9 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 3.0 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.3 | 2.8 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 0.2 | 2.8 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.1 | 2.6 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.3 | 2.4 | GO:0032596 | protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227) |
| 0.2 | 2.3 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.5 | 2.1 | GO:0035934 | corticosterone secretion(GO:0035934) |
| 0.3 | 2.1 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.1 | 2.1 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.1 | 2.1 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
| 0.1 | 2.1 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.5 | 2.0 | GO:0033128 | negative regulation of histone phosphorylation(GO:0033128) |
| 0.4 | 2.0 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
| 0.1 | 2.0 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.1 | 2.0 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 2.0 | GO:0035567 | non-canonical Wnt signaling pathway(GO:0035567) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 48.0 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.2 | 8.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 4.9 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 3.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 3.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 3.0 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 2.5 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.2 | 2.1 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 2.1 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 2.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.5 | 2.0 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.1 | 2.0 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 1.9 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 1.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 1.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.3 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 1.3 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 0.9 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.1 | 0.8 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 53 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 24.7 | GO:0005509 | calcium ion binding(GO:0005509) |
| 1.7 | 7.0 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.2 | 4.9 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.5 | 3.0 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 2.7 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.1 | 2.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 2.4 | GO:0020037 | heme binding(GO:0020037) |
| 0.1 | 2.3 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.5 | 2.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.2 | 2.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 2.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 2.0 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 2.0 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 1.9 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 1.8 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 1.8 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 1.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.4 | 1.7 | GO:0004096 | catalase activity(GO:0004096) |
| 0.2 | 1.7 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 0.1 | 1.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
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