Motif ID: Zbtb12

Z-value: 0.624


Transcription factors associated with Zbtb12:

Gene SymbolEntrez IDGene Name
Zbtb12 ENSMUSG00000049823.8 Zbtb12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_34894573-0.283.1e-02Click!


Activity profile for motif Zbtb12.

activity profile for motif Zbtb12


Sorted Z-values histogram for motif Zbtb12

Sorted Z-values for motif Zbtb12



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb12

PNG image of the network

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Top targets:


Showing 1 to 20 of 64 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_12027958 4.358 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr9_+_37367354 4.237 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr6_-_124814288 3.895 ENSMUST00000172132.2
 Tpi1
triosephosphate isomerase 1
chr3_-_84155762 3.599 ENSMUST00000047368.6
 Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr14_-_103844173 3.582 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr17_-_27029009 3.462 ENSMUST00000078691.5
 Bak1
BCL2-antagonist/killer 1
chr3_+_88081997 3.295 ENSMUST00000071812.5
 Iqgap3
IQ motif containing GTPase activating protein 3
chr4_-_151057933 3.253 ENSMUST00000030797.3
 Vamp3
vesicle-associated membrane protein 3
chr11_+_54902743 3.219 ENSMUST00000082430.3
 Gpx3
glutathione peroxidase 3
chr17_-_15375969 3.111 ENSMUST00000014917.7
 Dll1
delta-like 1 (Drosophila)
chr19_+_59260878 2.941 ENSMUST00000026084.3
 Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr11_+_54902917 2.916 ENSMUST00000149324.1
 Gpx3
glutathione peroxidase 3
chr18_-_70472429 2.915 ENSMUST00000067556.3
 4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr13_+_104229366 2.881 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr5_+_92603039 2.873 ENSMUST00000050952.3
 Stbd1
starch binding domain 1
chr11_-_88718078 2.536 ENSMUST00000092794.5
 Msi2
musashi RNA-binding protein 2
chr19_-_10240689 2.427 ENSMUST00000088013.5
 Myrf
myelin regulatory factor
chr4_+_32983417 2.317 ENSMUST00000084747.5
 Rragd
Ras-related GTP binding D
chr8_-_45382198 2.122 ENSMUST00000093526.6
 Fam149a
family with sequence similarity 149, member A
chr2_-_28916668 2.021 ENSMUST00000113847.1
 Barhl1
BarH-like 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.5 4.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 4.2 GO:0007050 cell cycle arrest(GO:0007050)
1.3 3.9 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.2 3.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 3.6 GO:0051321 meiotic cell cycle(GO:0051321)
1.2 3.5 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.4 3.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 3.3 GO:0035493 SNARE complex assembly(GO:0035493)
1.0 3.1 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.5 2.9 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 2.9 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 2.5 GO:0048864 stem cell development(GO:0048864)
0.3 2.4 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 2.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.0 GO:0030901 midbrain development(GO:0030901)
0.2 1.9 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.6 1.8 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.4 1.8 GO:0051012 microtubule sliding(GO:0051012)
0.5 1.6 GO:0018094 protein polyglycylation(GO:0018094)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.7 GO:0005615 extracellular space(GO:0005615)
0.0 3.6 GO:0031965 nuclear membrane(GO:0031965)
0.3 3.5 GO:0046930 pore complex(GO:0046930)
0.1 3.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 3.1 GO:0016324 apical plasma membrane(GO:0016324)
0.2 2.9 GO:0031045 dense core granule(GO:0031045)
0.0 2.5 GO:0005844 polysome(GO:0005844)
0.0 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.5 2.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.9 GO:0045178 basal part of cell(GO:0045178)
0.1 1.8 GO:0044447 axoneme part(GO:0044447)
0.0 1.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 1.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.1 GO:0008430 selenium binding(GO:0008430)
0.2 4.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 3.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.2 3.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 3.5 GO:0051400 BH domain binding(GO:0051400)
0.7 3.3 GO:0032027 myosin light chain binding(GO:0032027)
0.1 3.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 3.1 GO:0030957 Tat protein binding(GO:0030957)
1.0 2.9 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.7 2.9 GO:2001069 glycogen binding(GO:2001069)
0.1 2.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.4 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.3 1.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.8 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 0.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)