Motif ID: Zbtb14

Z-value: 2.071


Transcription factors associated with Zbtb14:

Gene SymbolEntrez IDGene Name
Zbtb14 ENSMUSG00000049672.8 Zbtb14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb14mm10_v2_chr17_+_69383319_69383394-0.057.1e-01Click!


Activity profile for motif Zbtb14.

activity profile for motif Zbtb14


Sorted Z-values histogram for motif Zbtb14

Sorted Z-values for motif Zbtb14



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_115194283 22.849 ENSMUST00000112113.1
 Cabp1
calcium binding protein 1
chr11_+_104231390 22.786 ENSMUST00000106992.3
 Mapt
microtubule-associated protein tau
chr6_-_32588192 22.311 ENSMUST00000115096.2
 Plxna4
plexin A4
chr11_+_104231573 22.297 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr11_+_104231515 20.450 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr1_-_132741750 20.282 ENSMUST00000094569.4
ENSMUST00000163770.1
 Nfasc

neurofascin

chr11_-_6065737 20.092 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
 Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr11_+_104231465 19.257 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr11_-_6065538 18.801 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr10_+_58813359 16.276 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr10_+_13966268 16.274 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_63212514 16.213 ENSMUST00000032738.5
 Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
chr9_-_58201705 14.695 ENSMUST00000163200.1
ENSMUST00000165276.1
 Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr12_-_100725028 13.595 ENSMUST00000043599.6
 Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr7_-_27396542 12.926 ENSMUST00000108363.1
 Sptbn4
spectrin beta, non-erythrocytic 4
chr2_-_104410334 12.913 ENSMUST00000089726.3
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr4_+_42917234 12.844 ENSMUST00000107976.2
ENSMUST00000069184.2
 N28178

expressed sequence N28178

chr19_-_46327121 12.633 ENSMUST00000041391.4
ENSMUST00000096029.5
 Psd

pleckstrin and Sec7 domain containing

chrX_-_73824938 12.566 ENSMUST00000114438.2
ENSMUST00000002080.5
 Pdzd4

PDZ domain containing 4

chr17_-_24689901 12.563 ENSMUST00000007236.4
 Syngr3
synaptogyrin 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 372 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.3 100.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
7.1 42.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
13.0 38.9 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
1.1 35.1 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.8 31.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.1 30.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
7.2 29.0 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
1.7 23.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 19.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
1.2 18.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.9 18.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.9 17.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.2 16.9 GO:0007416 synapse assembly(GO:0007416)
1.1 16.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
5.4 16.2 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
1.3 16.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.4 15.1 GO:0032482 Rab protein signal transduction(GO:0032482)
4.5 13.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.8 13.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.8 12.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 155 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.5 84.8 GO:0045298 tubulin complex(GO:0045298)
0.4 54.2 GO:0055037 recycling endosome(GO:0055037)
0.0 43.1 GO:0016021 integral component of membrane(GO:0016021)
1.3 38.9 GO:0051233 spindle midzone(GO:0051233)
0.6 36.6 GO:0031594 neuromuscular junction(GO:0031594)
0.3 31.3 GO:0043204 perikaryon(GO:0043204)
0.2 27.9 GO:0031225 anchored component of membrane(GO:0031225)
2.4 26.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 22.2 GO:0045211 postsynaptic membrane(GO:0045211)
3.6 21.7 GO:0008091 spectrin(GO:0008091)
5.3 21.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.7 20.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 20.3 GO:0030427 site of polarized growth(GO:0030427)
0.5 17.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.7 16.3 GO:0099738 cell cortex region(GO:0099738)
1.5 16.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.2 16.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 15.7 GO:0042734 presynaptic membrane(GO:0042734)
0.8 15.6 GO:0000421 autophagosome membrane(GO:0000421)
0.2 14.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 233 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 79.0 GO:0034185 apolipoprotein binding(GO:0034185)
1.7 39.9 GO:0043274 phospholipase binding(GO:0043274)
1.5 31.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
3.7 30.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 28.9 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
1.9 26.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 26.6 GO:0005509 calcium ion binding(GO:0005509)
0.1 23.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.5 23.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
4.3 21.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.9 21.7 GO:0030506 ankyrin binding(GO:0030506)
0.9 21.3 GO:0031489 myosin V binding(GO:0031489)
0.6 18.6 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.5 17.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.8 16.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 16.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 16.8 GO:0017124 SH3 domain binding(GO:0017124)
0.4 16.7 GO:0005158 insulin receptor binding(GO:0005158)
1.8 16.2 GO:0015643 toxic substance binding(GO:0015643)
1.8 16.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)