Motif ID: Zbtb18

Z-value: 1.339


Transcription factors associated with Zbtb18:

Gene SymbolEntrez IDGene Name
Zbtb18 ENSMUSG00000063659.6 Zbtb18

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177445660_177445821-0.759.9e-12Click!


Activity profile for motif Zbtb18.

activity profile for motif Zbtb18


Sorted Z-values histogram for motif Zbtb18

Sorted Z-values for motif Zbtb18



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb18

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_45311538 20.049 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr11_-_102365111 10.836 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr5_-_28467093 9.004 ENSMUST00000002708.3
 Shh
sonic hedgehog
chr6_+_5390387 7.046 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr18_+_50051702 6.781 ENSMUST00000134348.1
ENSMUST00000153873.2
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr10_+_78069351 6.430 ENSMUST00000105393.1
 Icosl
icos ligand
chr9_+_65630552 6.278 ENSMUST00000055844.8
 Rbpms2
RNA binding protein with multiple splicing 2
chrX_-_106485367 6.063 ENSMUST00000140707.1
 Fndc3c1
fibronectin type III domain containing 3C1
chr9_-_20976762 6.004 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr13_+_13437602 5.858 ENSMUST00000005532.7
 Nid1
nidogen 1
chr12_+_109743787 5.695 ENSMUST00000183068.1
 Mirg
miRNA containing gene
chr8_-_107403197 5.595 ENSMUST00000003947.8
 Nqo1
NAD(P)H dehydrogenase, quinone 1
chr7_-_19699008 5.384 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
 Apoe





apolipoprotein E





chr4_+_115088708 5.047 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
 Pdzk1ip1



PDZK1 interacting protein 1



chr3_-_97610156 4.862 ENSMUST00000029730.4
 Chd1l
chromodomain helicase DNA binding protein 1-like
chr17_-_10840285 4.699 ENSMUST00000041463.6
 Pacrg
PARK2 co-regulated
chr3_+_134236483 4.657 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr2_+_165655237 4.586 ENSMUST00000063433.7
 Eya2
eyes absent 2 homolog (Drosophila)
chr1_+_137928100 4.553 ENSMUST00000054333.2
 A130050O07Rik
RIKEN cDNA A130050O07 gene
chr14_-_122913085 4.444 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
 Ggact


gamma-glutamylamine cyclotransferase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 218 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.0 20.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 13.2 GO:0015701 bicarbonate transport(GO:0015701)
3.0 9.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.7 7.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 6.8 GO:0045475 locomotor rhythm(GO:0045475)
0.2 6.8 GO:0032611 interleukin-1 beta production(GO:0032611)
2.1 6.4 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
2.0 6.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.7 5.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.3 5.8 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.1 5.6 GO:0006801 superoxide metabolic process(GO:0006801)
1.8 5.4 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.1 5.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.3 4.9 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 4.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 4.7 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.7 4.6 GO:0016576 histone dephosphorylation(GO:0016576)
1.5 4.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
1.5 4.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.9 4.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 20.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 14.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 11.1 GO:0005884 actin filament(GO:0005884)
0.1 10.7 GO:0014704 intercalated disc(GO:0014704)
0.1 10.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 8.4 GO:0005604 basement membrane(GO:0005604)
0.1 7.4 GO:0005657 replication fork(GO:0005657)
1.8 7.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 5.9 GO:0005605 basal lamina(GO:0005605)
0.0 5.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.8 5.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 5.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 4.5 GO:0019866 organelle inner membrane(GO:0019866)
0.1 4.3 GO:0044306 neuron projection terminus(GO:0044306)
0.1 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.1 GO:0016592 mediator complex(GO:0016592)
0.0 4.0 GO:0005813 centrosome(GO:0005813)
1.3 3.8 GO:0031983 vesicle lumen(GO:0031983)
0.1 3.7 GO:0005882 intermediate filament(GO:0005882)
0.0 3.7 GO:0005819 spindle(GO:0005819)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 20.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
2.1 14.9 GO:0043237 laminin-1 binding(GO:0043237)
0.8 13.2 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 10.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 9.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 7.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 7.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.8 6.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.4 5.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.8 5.4 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 5.0 GO:0030332 cyclin binding(GO:0030332)
0.1 4.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 4.7 GO:0017166 vinculin binding(GO:0017166)
0.2 4.7 GO:0043014 alpha-tubulin binding(GO:0043014)
1.5 4.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.5 4.4 GO:0005534 galactose binding(GO:0005534)
1.5 4.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 4.4 GO:0005522 profilin binding(GO:0005522)
0.9 4.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 4.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)