Motif ID: Zbtb3
Z-value: 0.585
Transcription factors associated with Zbtb3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zbtb3 | ENSMUSG00000071661.6 | Zbtb3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb3 | mm10_v2_chr19_+_8802486_8802530 | 0.53 | 1.8e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
| 0.3 | 0.9 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
| 0.3 | 2.9 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.3 | 1.1 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.2 | 0.6 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
| 0.2 | 0.6 | GO:0030070 | insulin processing(GO:0030070) |
| 0.2 | 1.1 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.2 | 0.5 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 0.2 | 1.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 0.4 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.1 | 0.4 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
| 0.1 | 1.8 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) membrane hyperpolarization(GO:0060081) |
| 0.1 | 0.6 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 1.3 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
| 0.1 | 1.5 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.1 | 0.9 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 0.4 | GO:2001015 | negative regulation of skeletal muscle cell differentiation(GO:2001015) |
| 0.1 | 1.8 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 0.4 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 0.9 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.1 | 0.8 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.1 | 0.8 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 0.3 | GO:0032439 | endosome localization(GO:0032439) |
| 0.1 | 0.7 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.1 | 0.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.2 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.1 | 0.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 1.0 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.1 | 0.6 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.0 | 0.7 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.0 | 4.4 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.0 | 0.3 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
| 0.0 | 1.2 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.0 | 0.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.7 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.0 | 0.5 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 1.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.4 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
| 0.0 | 0.2 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.0 | 0.1 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.0 | 0.1 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.0 | 0.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.4 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.0 | 0.2 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.8 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 0.3 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
| 0.0 | 0.2 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.0 | 0.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.7 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.2 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.4 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
| 0.0 | 0.1 | GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030) |
| 0.0 | 0.1 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.1 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 1.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 1.0 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 2.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 4.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 0.9 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.0 | 0.3 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.6 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 2.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 2.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.9 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.9 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.8 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 2.4 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.2 | 1.8 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.2 | 0.6 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
| 0.2 | 0.6 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.2 | 1.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.2 | 0.8 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 0.4 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 0.1 | 1.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.8 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.8 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 0.8 | GO:0045703 | pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703) |
| 0.1 | 0.4 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.1 | 0.9 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 0.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 2.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 1.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.6 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.1 | 0.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.1 | 0.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.5 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.0 | 0.6 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897) |
| 0.0 | 0.1 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.0 | 4.7 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 0.9 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) angiostatin binding(GO:0043532) |
| 0.0 | 0.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.9 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.0 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.0 | 1.2 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.2 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.0 | 0.7 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 2.0 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
| 0.0 | 0.9 | GO:0005262 | calcium channel activity(GO:0005262) |
