Motif ID: Zbtb49

Z-value: 0.338


Transcription factors associated with Zbtb49:

Gene SymbolEntrez IDGene Name
Zbtb49 ENSMUSG00000029127.9 Zbtb49

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb49mm10_v2_chr5_-_38220400_382204590.613.6e-07Click!


Activity profile for motif Zbtb49.

activity profile for motif Zbtb49


Sorted Z-values histogram for motif Zbtb49

Sorted Z-values for motif Zbtb49



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb49

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_140154712 3.426 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr9_+_45430293 3.365 ENSMUST00000034592.8
Dscaml1
Down syndrome cell adhesion molecule like 1
chr18_-_61911783 2.492 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr9_+_40269430 2.420 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40269202 2.164 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b

sodium channel, voltage-gated, type III, beta

chr1_+_32172711 2.112 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr9_+_40269273 2.081 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr12_+_89812467 0.822 ENSMUST00000110133.2
ENSMUST00000110130.2
Nrxn3

neurexin III

chr5_-_108629712 0.820 ENSMUST00000046603.8
Gak
cyclin G associated kinase
chr9_+_50856924 0.761 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chr7_+_4460687 0.757 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr18_+_23753708 0.733 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_+_108629990 0.605 ENSMUST00000078323.6
ENSMUST00000120327.1
Tmem175

transmembrane protein 175

chr5_+_108629791 0.564 ENSMUST00000063272.6
Tmem175
transmembrane protein 175
chr15_-_102257449 0.520 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr15_-_102257306 0.474 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr16_-_70382385 0.458 ENSMUST00000072455.4
4930423O20Rik
RIKEN cDNA 4930423O20 gene
chr1_-_183369529 0.385 ENSMUST00000069922.5
Mia3
melanoma inhibitory activity 3
chr8_+_4493443 0.384 ENSMUST00000175781.2
Cers4
ceramide synthase 4
chr3_-_53017195 0.314 ENSMUST00000036665.4
Cog6
component of oligomeric golgi complex 6
chr17_+_32993123 0.184 ENSMUST00000087666.4
ENSMUST00000157017.1
Zfp952

zinc finger protein 952

chr6_+_59208870 0.133 ENSMUST00000062626.3
Tigd2
tigger transposable element derived 2
chr17_+_24736639 0.004 ENSMUST00000115262.1
Msrb1
methionine sulfoxide reductase B1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4 3.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 1.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.1 1.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.8 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 2.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0002063 chondrocyte development(GO:0002063)
0.0 3.4 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.1 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 1.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)