Motif ID: Zbtb6

Z-value: 0.746


Transcription factors associated with Zbtb6:

Gene SymbolEntrez IDGene Name
Zbtb6 ENSMUSG00000066798.3 Zbtb6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb6mm10_v2_chr2_-_37430835_374309190.211.1e-01Click!


Activity profile for motif Zbtb6.

activity profile for motif Zbtb6


Sorted Z-values histogram for motif Zbtb6

Sorted Z-values for motif Zbtb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102897123 7.174 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr11_-_102897146 5.186 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr6_+_114131229 4.768 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr1_-_133131782 4.720 ENSMUST00000180528.1
 Gm26616
predicted gene, 26616
chr5_+_36796228 4.374 ENSMUST00000181278.1
 Gm26605
predicted gene, 26605
chr14_+_27238018 3.841 ENSMUST00000049206.5
 Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr17_+_47410247 3.796 ENSMUST00000177586.1
 Gm5814
predicted pseudogene 5814
chr12_-_83951355 3.778 ENSMUST00000181399.1
 Gm26571
predicted gene, 26571
chr6_+_124997062 3.049 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein
chr3_+_54156039 3.016 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr11_-_114066174 2.862 ENSMUST00000041627.7
 Sdk2
sidekick homolog 2 (chicken)
chr4_-_120287349 2.856 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr10_-_80260959 2.832 ENSMUST00000020359.6
 Gamt
guanidinoacetate methyltransferase
chr10_-_80261004 2.716 ENSMUST00000105363.1
 Gamt
guanidinoacetate methyltransferase
chr18_+_37504264 2.661 ENSMUST00000052179.6
 Pcdhb20
protocadherin beta 20
chr11_+_101246405 2.548 ENSMUST00000122006.1
ENSMUST00000151830.1
 Ramp2

receptor (calcitonin) activity modifying protein 2

chr5_+_135806859 2.542 ENSMUST00000126232.1
 Srrm3
serine/arginine repetitive matrix 3
chr10_+_7589788 2.508 ENSMUST00000134346.1
ENSMUST00000019931.5
 Lrp11

low density lipoprotein receptor-related protein 11

chr16_-_45158453 2.455 ENSMUST00000181750.1
 Slc35a5
solute carrier family 35, member A5
chr6_+_124996681 2.416 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 12.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.4 8.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 6.5 GO:0008643 carbohydrate transport(GO:0008643)
1.8 5.5 GO:0006601 creatine biosynthetic process(GO:0006601)
1.2 4.8 GO:0009414 response to water deprivation(GO:0009414)
0.4 4.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 3.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.3 3.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 2.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 2.9 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 2.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.4 2.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 2.2 GO:0009404 toxin metabolic process(GO:0009404)
0.2 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.1 GO:0008360 regulation of cell shape(GO:0008360)
0.3 2.0 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.6 1.9 GO:0061743 motor learning(GO:0061743)
0.5 1.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 1.9 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 1.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 12.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 11.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 9.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 7.3 GO:0043235 receptor complex(GO:0043235)
0.0 7.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.1 GO:0030141 secretory granule(GO:0030141)
0.4 1.9 GO:0044301 climbing fiber(GO:0044301)
0.1 1.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.7 GO:0010008 endosome membrane(GO:0010008)
0.5 1.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.2 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.2 GO:0070938 contractile ring(GO:0070938)
0.1 1.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.3 1.0 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 12.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 8.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
1.6 4.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 4.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 4.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 3.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.4 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.3 3.0 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 2.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 2.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 2.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 2.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.6 1.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.6 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 1.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)