Motif ID: Zbtb7b

Z-value: 1.035


Transcription factors associated with Zbtb7b:

Gene SymbolEntrez IDGene Name
Zbtb7b ENSMUSG00000028042.9 Zbtb7b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7bmm10_v2_chr3_-_89393294_893933780.401.7e-03Click!


Activity profile for motif Zbtb7b.

activity profile for motif Zbtb7b


Sorted Z-values histogram for motif Zbtb7b

Sorted Z-values for motif Zbtb7b



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7b

PNG image of the network

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Top targets:


Showing 1 to 20 of 195 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_105471481 9.650 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr10_+_84756055 8.575 ENSMUST00000060397.6
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr17_+_85620816 7.527 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr7_-_127122226 6.350 ENSMUST00000032912.5
 Qprt
quinolinate phosphoribosyltransferase
chr5_+_137350371 6.290 ENSMUST00000166239.1
ENSMUST00000111054.1
 Ephb4

Eph receptor B4

chr11_+_120948480 6.190 ENSMUST00000070653.6
 Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr17_+_34592248 6.060 ENSMUST00000038149.6
 Pbx2
pre B cell leukemia homeobox 2
chr11_+_108920800 6.051 ENSMUST00000140821.1
 Axin2
axin2
chr8_-_87959560 5.978 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr13_-_53473074 5.289 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr11_-_75422586 5.282 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr17_+_23679363 5.068 ENSMUST00000024699.2
 Cldn6
claudin 6
chr14_-_70642268 4.976 ENSMUST00000022697.5
 Fgf17
fibroblast growth factor 17
chr5_+_139543889 4.960 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr7_-_142657466 4.831 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr19_+_55742242 4.776 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
 Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr2_-_117342709 4.765 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
 Rasgrp1


RAS guanyl releasing protein 1


chr2_-_117342949 4.609 ENSMUST00000102534.4
 Rasgrp1
RAS guanyl releasing protein 1
chr3_+_34649987 4.598 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr7_-_126799163 4.572 ENSMUST00000032934.5
 Aldoa
aldolase A, fructose-bisphosphate

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 13.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
2.8 11.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 9.7 GO:0046785 microtubule polymerization(GO:0046785)
1.1 9.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.9 9.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.7 8.6 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.4 8.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
2.5 7.5 GO:0097402 neuroblast migration(GO:0097402)
0.9 7.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.6 6.3 GO:0046874 quinolinate metabolic process(GO:0046874)
1.6 6.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 6.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 5.9 GO:0008360 regulation of cell shape(GO:0008360)
0.3 5.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 5.7 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
1.8 5.3 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.7 5.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 5.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.6 4.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.7 4.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 15.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.5 11.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 9.6 GO:0043203 axon hillock(GO:0043203)
0.6 9.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 6.4 GO:0005871 kinesin complex(GO:0005871)
0.5 4.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 4.5 GO:0030061 mitochondrial crista(GO:0030061)
0.8 4.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 4.0 GO:0097542 ciliary tip(GO:0097542)
0.1 4.0 GO:0034451 centriolar satellite(GO:0034451)
0.6 3.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 3.9 GO:0005901 caveola(GO:0005901)
0.2 3.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 3.2 GO:0042587 glycogen granule(GO:0042587)
0.0 3.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.9 GO:0051233 spindle midzone(GO:0051233)
0.1 2.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 2.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.2 13.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 11.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 9.7 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 9.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.5 9.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.5 8.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 7.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 7.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 6.4 GO:0003777 microtubule motor activity(GO:0003777)
0.3 6.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 6.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 5.9 GO:0016791 phosphatase activity(GO:0016791)
1.7 5.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 4.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 4.6 GO:0035198 miRNA binding(GO:0035198)
0.2 4.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 4.5 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 4.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.0 4.1 GO:0008142 oxysterol binding(GO:0008142)