Motif ID: Zbtb7c

Z-value: 1.048


Transcription factors associated with Zbtb7c:

Gene SymbolEntrez IDGene Name
Zbtb7c ENSMUSG00000044646.8 Zbtb7c

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7cmm10_v2_chr18_+_76059458_760595010.162.2e-01Click!


Activity profile for motif Zbtb7c.

activity profile for motif Zbtb7c


Sorted Z-values histogram for motif Zbtb7c

Sorted Z-values for motif Zbtb7c



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7c

PNG image of the network

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Top targets:


Showing 1 to 20 of 122 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_127263346 15.067 ENSMUST00000099172.3
 Kif5a
kinesin family member 5A
chr11_+_104231573 13.718 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr11_+_104231515 12.229 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr2_-_29253001 12.020 ENSMUST00000071201.4
 Ntng2
netrin G2
chr11_+_104231465 11.845 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr18_+_32938955 11.431 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr4_-_120287349 9.072 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr10_+_93589413 8.054 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr16_+_11984581 6.761 ENSMUST00000170672.2
ENSMUST00000023138.7
 Shisa9

shisa homolog 9 (Xenopus laevis)

chr11_+_75531690 6.175 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
 Slc43a2



solute carrier family 43, member 2



chr6_+_51432678 5.982 ENSMUST00000160133.1
 Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr11_-_26210553 5.939 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr3_+_107036156 5.574 ENSMUST00000052718.3
 Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr1_-_21961581 5.437 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
 Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr6_+_51432663 5.308 ENSMUST00000005103.5
 Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr10_-_79874211 5.258 ENSMUST00000167897.1
 BC005764
cDNA sequence BC005764
chr8_+_25911670 5.054 ENSMUST00000120653.1
ENSMUST00000126226.1
 Kcnu1

potassium channel, subfamily U, member 1

chr12_-_109068173 4.926 ENSMUST00000073156.7
 Begain
brain-enriched guanylate kinase-associated
chr12_+_31265279 4.767 ENSMUST00000002979.8
ENSMUST00000170495.1
 Lamb1

laminin B1

chr9_-_108190352 4.732 ENSMUST00000035208.7
 Bsn
bassoon

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 37.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 16.0 GO:0007409 axonogenesis(GO:0007409)
0.1 15.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 14.5 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.2 12.9 GO:0015807 L-amino acid transport(GO:0015807)
0.7 11.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
2.3 9.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 9.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 7.1 GO:0035418 protein localization to synapse(GO:0035418)
0.4 6.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 4.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 4.4 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3 4.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 4.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.5 3.8 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.9 3.7 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.7 3.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
1.1 3.4 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 3.3 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.4 3.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.8 37.8 GO:0045298 tubulin complex(GO:0045298)
0.0 24.2 GO:0005730 nucleolus(GO:0005730)
1.0 15.1 GO:0035253 ciliary rootlet(GO:0035253)
0.2 15.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 14.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 12.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.4 12.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.7 6.8 GO:0032591 dendritic spine membrane(GO:0032591)
1.6 6.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.3 4.7 GO:0097470 ribbon synapse(GO:0097470)
0.3 3.8 GO:0043196 varicosity(GO:0043196)
0.7 3.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 3.1 GO:0043034 costamere(GO:0043034)
0.0 2.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.6 2.6 GO:0045098 type III intermediate filament(GO:0045098)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 2.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 2.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.0 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 37.8 GO:0034185 apolipoprotein binding(GO:0034185)
1.0 15.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 12.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 12.4 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.5 11.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 7.8 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 7.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.8 6.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 6.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 5.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.5 5.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 5.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.7 5.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 4.5 GO:0070412 R-SMAD binding(GO:0070412)
0.2 4.2 GO:0071837 HMG box domain binding(GO:0071837)
0.3 3.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 3.8 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 3.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 3.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 3.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)