Motif ID: Zfhx3

Z-value: 0.960


Transcription factors associated with Zfhx3:

Gene SymbolEntrez IDGene Name
Zfhx3 ENSMUSG00000038872.8 Zfhx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfhx3mm10_v2_chr8_+_108714644_108714644-0.123.8e-01Click!


Activity profile for motif Zfhx3.

activity profile for motif Zfhx3


Sorted Z-values histogram for motif Zfhx3

Sorted Z-values for motif Zfhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfhx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 87 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_143933204 13.714 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr13_-_110280103 13.477 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chrX_-_143933089 12.037 ENSMUST00000087313.3
 Dcx
doublecortin
chr10_-_110000219 9.854 ENSMUST00000032719.7
 Nav3
neuron navigator 3
chr1_-_126830632 7.365 ENSMUST00000112583.1
ENSMUST00000094609.3
 Nckap5

NCK-associated protein 5

chr3_+_28263205 7.206 ENSMUST00000159236.2
 Tnik
TRAF2 and NCK interacting kinase
chr14_+_64588112 7.108 ENSMUST00000181808.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chr17_+_35076902 6.863 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr4_+_13743424 6.822 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_101507947 6.524 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr6_-_101377897 6.040 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr16_-_74411776 5.806 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr1_-_158814469 5.788 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr18_+_37518341 5.678 ENSMUST00000097609.1
 Pcdhb22
protocadherin beta 22
chr11_+_24078173 5.662 ENSMUST00000109514.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr9_+_86485407 5.647 ENSMUST00000034987.8
 Dopey1
dopey family member 1
chr2_+_82053222 5.163 ENSMUST00000047527.7
 Zfp804a
zinc finger protein 804A
chr3_+_136670076 4.838 ENSMUST00000070198.7
 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr5_+_107497718 4.674 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr11_+_24078022 4.517 ENSMUST00000000881.6
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 25.8 GO:0021860 pyramidal neuron development(GO:0021860)
1.1 14.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 12.1 GO:0019882 antigen processing and presentation(GO:0019882)
1.4 7.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 6.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 6.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
1.1 6.5 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 6.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 6.0 GO:0007528 neuromuscular junction development(GO:0007528)
1.9 5.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 5.7 GO:0007097 nuclear migration(GO:0007097)
1.6 4.8 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.6 4.7 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.3 4.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 3.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 3.6 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 3.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.5 3.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 2.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 2.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 24.1 GO:0005874 microtubule(GO:0005874)
0.1 13.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 10.5 GO:0016604 nuclear body(GO:0016604)
0.0 9.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 7.2 GO:0055037 recycling endosome(GO:0055037)
0.1 6.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 6.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 6.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 6.0 GO:0005635 nuclear envelope(GO:0005635)
0.2 5.8 GO:0030673 axolemma(GO:0030673)
0.1 5.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 5.7 GO:0042641 actomyosin(GO:0042641)
0.8 4.8 GO:0005955 calcineurin complex(GO:0005955)
0.1 4.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 3.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 3.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.3 GO:0005814 centriole(GO:0005814)
1.0 3.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 2.3 GO:0045275 respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 25.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 14.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.6 13.5 GO:0031489 myosin V binding(GO:0031489)
0.1 7.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
2.3 6.9 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 6.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 6.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 6.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 6.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.6 5.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 5.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.8 4.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 4.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 4.5 GO:0008565 protein transporter activity(GO:0008565)
0.4 4.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 3.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 2.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 2.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.6 2.4 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)