Motif ID: Zfp105

Z-value: 0.807


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_122923099-0.211.1e-01Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_99006056 9.595 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr15_-_81843699 9.354 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr8_-_84773381 8.475 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr10_-_96409038 7.394 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr5_+_17574268 6.378 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_109251698 5.388 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr8_+_128359065 5.312 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr5_+_13399309 4.811 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr18_+_69344503 4.642 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr12_-_90738438 4.071 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr4_+_144892813 3.901 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr14_+_11227511 3.559 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr13_-_21501418 3.481 ENSMUST00000044043.2
 Gm11273
predicted gene 11273
chr5_+_19907502 2.313 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_67609667 2.263 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr14_-_36968679 2.016 ENSMUST00000067700.6
 Ccser2
coiled-coil serine rich 2
chr18_+_37484955 1.897 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr4_+_11704439 1.802 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr8_+_93810832 1.740 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr8_-_106573461 1.694 ENSMUST00000073722.5
 Gm10073
predicted pseudogene 10073
chr13_-_67609617 1.530 ENSMUST00000138725.1
 AA987161
expressed sequence AA987161
chr6_-_142964404 1.274 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_-_101466222 1.096 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)
chr6_-_99632376 0.872 ENSMUST00000176255.1
 Gm20696
predicted gene 20696
chr4_+_105157339 0.871 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr9_-_19928282 0.859 ENSMUST00000082002.5
 Gm7808
predicted pseudogene 7808
chr2_-_177267036 0.808 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr18_+_30272747 0.758 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
 Pik3c3


phosphoinositide-3-kinase, class 3


chr18_+_35770318 0.743 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr15_+_78983041 0.730 ENSMUST00000109687.1
ENSMUST00000109688.1
ENSMUST00000130663.2
 Triobp


TRIO and F-actin binding protein


chr11_-_100411874 0.728 ENSMUST00000141840.1
 Leprel4
leprecan-like 4
chr5_-_111761697 0.711 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr1_+_179960472 0.625 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr9_+_78175898 0.598 ENSMUST00000180974.1
 C920006O11Rik
RIKEN cDNA C920006O11 gene
chr8_+_20567716 0.576 ENSMUST00000178995.1
 Gm21092
predicted gene, 21092
chr6_-_127151044 0.537 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr5_+_136953246 0.465 ENSMUST00000111094.1
ENSMUST00000111097.1
 Fis1

fission 1 (mitochondrial outer membrane) homolog (yeast)

chr14_+_31019159 0.400 ENSMUST00000112094.1
ENSMUST00000144009.1
 Pbrm1

polybromo 1

chr17_+_6079928 0.316 ENSMUST00000100955.2
 Gtf2h5
general transcription factor IIH, polypeptide 5
chr2_+_107290590 0.261 ENSMUST00000037012.2
 Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr19_-_53464721 0.244 ENSMUST00000180489.1
 5830416P10Rik
RIKEN cDNA 5830416P10 gene
chr1_+_171419027 0.234 ENSMUST00000171362.1
 Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr6_-_53820764 0.168 ENSMUST00000127748.2
 Tril
TLR4 interactor with leucine-rich repeats
chr8_-_57487801 0.142 ENSMUST00000034022.3
 Sap30
sin3 associated polypeptide
chr11_-_22286795 0.065 ENSMUST00000109563.2
ENSMUST00000180360.1
 Ehbp1

EH domain binding protein 1

chr1_-_63114516 0.058 ENSMUST00000097718.2
 Ino80d
INO80 complex subunit D
chr1_-_184732616 0.049 ENSMUST00000048572.6
 Hlx
H2.0-like homeobox
chr12_-_99393010 0.038 ENSMUST00000177451.1
 Foxn3
forkhead box N3
chr18_+_35829798 0.009 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 16.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.8 4.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.6 8.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 4.6 GO:0042118 endothelial cell activation(GO:0042118)
0.4 3.9 GO:0042572 retinol metabolic process(GO:0042572)
0.3 2.3 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.3 1.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 1.7 GO:0051926 dopamine receptor signaling pathway(GO:0007212) negative regulation of calcium ion transport(GO:0051926)
0.0 1.8 GO:0051310 metaphase plate congression(GO:0051310)
0.0 1.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0097443 sorting endosome(GO:0097443)
0.5 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.8 GO:0051233 spindle midzone(GO:0051233)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 4.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 10.5 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.1 5.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.0 11.2 GO:0038191 neuropilin binding(GO:0038191)
0.6 3.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.7 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.1 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)