Motif ID: Zfp219_Zfp740

Z-value: 0.945

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp740mm10_v2_chr15_+_102203639_1022037090.364.8e-03Click!
Zfp219mm10_v2_chr14_-_52020698_520207370.133.4e-01Click!


Activity profile for motif Zfp219_Zfp740.

activity profile for motif Zfp219_Zfp740


Sorted Z-values histogram for motif Zfp219_Zfp740

Sorted Z-values for motif Zfp219_Zfp740



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_29984219 5.277 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr2_+_48949495 4.613 ENSMUST00000112745.1
 Mbd5
methyl-CpG binding domain protein 5
chr16_+_44173271 3.634 ENSMUST00000088356.4
ENSMUST00000169582.1
 Gm608

predicted gene 608

chr7_+_127777095 3.388 ENSMUST00000144406.1
 Setd1a
SET domain containing 1A
chr12_-_27342696 3.287 ENSMUST00000079063.5
 Sox11
SRY-box containing gene 11
chr6_+_120666388 2.957 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr16_+_44173239 2.767 ENSMUST00000119746.1
 Gm608
predicted gene 608
chrX_-_94123087 2.589 ENSMUST00000113925.1
 Zfx
zinc finger protein X-linked
chr12_-_118301429 2.428 ENSMUST00000026367.9
 Sp4
trans-acting transcription factor 4
chr2_-_116065798 2.345 ENSMUST00000110907.1
ENSMUST00000110908.2
 Meis2

Meis homeobox 2

chr2_+_31640037 2.287 ENSMUST00000113470.2
 Prdm12
PR domain containing 12
chr3_+_41564880 2.283 ENSMUST00000168086.1
 Phf17
PHD finger protein 17
chr1_-_64121389 2.223 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr19_+_41482632 2.215 ENSMUST00000067795.5
 Lcor
ligand dependent nuclear receptor corepressor
chr7_+_127511976 2.180 ENSMUST00000098025.4
 Srcap
Snf2-related CREBBP activator protein
chr14_+_21500879 2.139 ENSMUST00000182964.1
 Kat6b
K(lysine) acetyltransferase 6B
chr19_-_59170978 2.135 ENSMUST00000172821.2
 Vax1
ventral anterior homeobox containing gene 1
chr6_+_4903350 2.061 ENSMUST00000175962.1
 Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr4_-_3938354 2.060 ENSMUST00000003369.3
 Plag1
pleiomorphic adenoma gene 1
chr9_-_44881274 2.021 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
 Kmt2a


lysine (K)-specific methyltransferase 2A



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 217 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.5 4.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 4.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 4.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 4.1 GO:1990403 embryonic brain development(GO:1990403)
0.3 4.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 4.0 GO:0006334 nucleosome assembly(GO:0006334)
0.3 3.8 GO:0060746 parental behavior(GO:0060746)
1.1 3.3 GO:0060023 soft palate development(GO:0060023)
0.4 3.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
1.1 3.2 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.5 3.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.6 2.8 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.3 2.8 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 2.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.7 2.7 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.5 2.7 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 2.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 2.5 GO:0001842 neural fold formation(GO:0001842)
0.2 2.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.9 GO:0005667 transcription factor complex(GO:0005667)
0.3 5.6 GO:0010369 chromocenter(GO:0010369)
0.0 4.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
1.1 4.4 GO:0090537 CERF complex(GO:0090537)
0.0 4.3 GO:0032993 protein-DNA complex(GO:0032993)
0.3 4.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 4.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 3.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 3.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 2.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.8 GO:1990391 DNA repair complex(GO:1990391)
0.5 2.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 2.7 GO:0032584 growth cone membrane(GO:0032584)
0.8 2.5 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 2.2 GO:0005844 polysome(GO:0005844)
0.1 2.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.0 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 137 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 39.4 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 4.9 GO:0003682 chromatin binding(GO:0003682)
0.6 4.2 GO:1990188 euchromatin binding(GO:1990188)
0.2 4.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 4.0 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.3 3.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 3.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 3.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 3.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 2.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 2.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 2.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 2.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 2.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.7 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) DNA-methyltransferase activity(GO:0009008) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.3 2.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 2.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.5 GO:0001222 transcription corepressor binding(GO:0001222)