Motif ID: Zfp691

Z-value: 0.416


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.094.9e-01Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_128601106 2.324 ENSMUST00000117102.2
 Fzd10
frizzled homolog 10 (Drosophila)
chr13_+_53525703 1.947 ENSMUST00000081132.4
 Gm5449
predicted pseudogene 5449
chr10_+_81183263 1.281 ENSMUST00000047665.6
 Dapk3
death-associated protein kinase 3
chr8_+_72319033 1.206 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr2_-_10130638 1.165 ENSMUST00000042290.7
 Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr10_-_86732409 1.100 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr9_+_62858085 0.957 ENSMUST00000034777.6
ENSMUST00000163820.1
 Calml4

calmodulin-like 4

chr9_-_58202281 0.859 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_+_28863831 0.819 ENSMUST00000138272.1
 Lgals7
lectin, galactose binding, soluble 7
chr4_-_129623870 0.730 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
 Ccdc28b


coiled coil domain containing 28B


chr6_+_134640940 0.728 ENSMUST00000062755.8
 Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr2_+_181715005 0.704 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
 Oprl1


opioid receptor-like 1


chr10_+_81183000 0.694 ENSMUST00000178422.1
 Dapk3
death-associated protein kinase 3
chr9_-_106887000 0.678 ENSMUST00000055843.7
 Rbm15b
RNA binding motif protein 15B
chr2_+_29802626 0.670 ENSMUST00000080065.2
 Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr10_-_81183849 0.667 ENSMUST00000056086.4
 4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr19_+_11516473 0.663 ENSMUST00000163078.1
 Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr13_-_60897439 0.626 ENSMUST00000171347.1
ENSMUST00000021884.8
 Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr3_-_92429403 0.559 ENSMUST00000047300.7
 Gm9774
predicted pseudogene 9774
chr9_-_108452377 0.551 ENSMUST00000035232.7
 Klhdc8b
kelch domain containing 8B
chr11_-_75422586 0.546 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr10_+_115569986 0.528 ENSMUST00000173620.1
 A930009A15Rik
RIKEN cDNA A930009A15 gene
chr7_+_143069249 0.516 ENSMUST00000060433.3
ENSMUST00000133410.2
ENSMUST00000105920.1
ENSMUST00000177841.1
ENSMUST00000147995.1
ENSMUST00000137856.1
 Tssc4





tumor-suppressing subchromosomal transferable fragment 4





chr1_+_51289106 0.509 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr1_-_138856819 0.509 ENSMUST00000112025.1
 2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr2_+_26591423 0.493 ENSMUST00000152988.2
ENSMUST00000149789.1
 Egfl7

EGF-like domain 7

chr10_+_60003321 0.491 ENSMUST00000164083.2
 Ascc1
activating signal cointegrator 1 complex subunit 1
chr2_-_155729359 0.486 ENSMUST00000040833.4
 Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr8_+_88521344 0.484 ENSMUST00000034086.5
 Nkd1
naked cuticle 1 homolog (Drosophila)
chr10_-_112928974 0.472 ENSMUST00000099276.2
 Atxn7l3b
ataxin 7-like 3B
chr13_-_34130345 0.448 ENSMUST00000075774.3
 Tubb2b
tubulin, beta 2B class IIB
chr8_+_69808672 0.440 ENSMUST00000036074.8
ENSMUST00000123453.1
 Gmip

Gem-interacting protein

chr7_-_45061706 0.439 ENSMUST00000107832.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr1_+_134193432 0.422 ENSMUST00000038445.6
 Mybph
myosin binding protein H
chr9_+_50603892 0.415 ENSMUST00000044051.4
 Timm8b
translocase of inner mitochondrial membrane 8B
chr15_+_82252397 0.406 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr6_+_28475101 0.404 ENSMUST00000168362.1
 Snd1
staphylococcal nuclease and tudor domain containing 1
chr8_-_22805596 0.404 ENSMUST00000163739.1
 Ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr7_-_45061651 0.395 ENSMUST00000007981.3
ENSMUST00000107831.1
 Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

chrX_-_101268218 0.394 ENSMUST00000033664.7
 Il2rg
interleukin 2 receptor, gamma chain
chr8_+_3621529 0.375 ENSMUST00000156380.2
 Pet100
PET100 homolog (S. cerevisiae)
chr13_+_55622999 0.370 ENSMUST00000021963.4
 Caml
calcium modulating ligand
chr5_+_37050854 0.366 ENSMUST00000043794.4
 Jakmip1
janus kinase and microtubule interacting protein 1
chr15_-_83555681 0.359 ENSMUST00000061882.8
 Mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr3_+_133338936 0.349 ENSMUST00000150386.1
ENSMUST00000125858.1
 Ppa2

pyrophosphatase (inorganic) 2

chr3_-_62605140 0.324 ENSMUST00000058535.5
 Gpr149
G protein-coupled receptor 149
chr3_-_33143025 0.313 ENSMUST00000108226.1
 Pex5l
peroxisomal biogenesis factor 5-like
chr2_+_24962400 0.313 ENSMUST00000028351.3
 Dph7
diphthamine biosynethesis 7
chr5_+_35893319 0.313 ENSMUST00000064571.4
 Afap1
actin filament associated protein 1
chr10_-_60002993 0.312 ENSMUST00000182116.1
 Anapc16
anaphase promoting complex subunit 16
chr3_-_67515487 0.310 ENSMUST00000178314.1
ENSMUST00000054825.4
 Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr4_+_126046903 0.309 ENSMUST00000030675.7
 Mrps15
mitochondrial ribosomal protein S15
chr4_+_129189760 0.308 ENSMUST00000106054.2
ENSMUST00000001365.2
 Yars

tyrosyl-tRNA synthetase

chr6_+_145934113 0.301 ENSMUST00000032383.7
 Sspn
sarcospan
chr4_+_132535542 0.295 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
 Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr14_+_119138415 0.295 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr8_-_124569696 0.290 ENSMUST00000063278.6
 Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr15_-_76723814 0.288 ENSMUST00000036247.8
 C030006K11Rik
RIKEN cDNA C030006K11 gene
chr2_+_91265252 0.280 ENSMUST00000028691.6
 Arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr2_-_130664565 0.263 ENSMUST00000089559.4
 Ddrgk1
DDRGK domain containing 1
chr10_-_60003056 0.248 ENSMUST00000182912.1
ENSMUST00000020307.4
ENSMUST00000182898.1
 Anapc16


anaphase promoting complex subunit 16


chr8_+_91313529 0.228 ENSMUST00000069718.7
 Fto
fat mass and obesity associated
chr8_+_123235086 0.219 ENSMUST00000181432.1
 4933417D19Rik
RIKEN cDNA 4933417D19 gene
chr12_+_86678685 0.219 ENSMUST00000021681.3
 Vash1
vasohibin 1
chr10_-_77166545 0.216 ENSMUST00000081654.6
 Col18a1
collagen, type XVIII, alpha 1
chr13_-_54468805 0.202 ENSMUST00000026990.5
 Thoc3
THO complex 3
chr9_-_21067093 0.198 ENSMUST00000115494.2
 Zglp1
zinc finger, GATA-like protein 1
chr11_-_120467414 0.187 ENSMUST00000076921.6
 Arl16
ADP-ribosylation factor-like 16
chr6_+_88465409 0.177 ENSMUST00000032165.9
 Ruvbl1
RuvB-like protein 1
chr11_+_120467635 0.171 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
 Hgs



HGF-regulated tyrosine kinase substrate



chr9_-_50603792 0.168 ENSMUST00000000175.4
 Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr5_+_95956916 0.160 ENSMUST00000023840.5
 Cxcl13
chemokine (C-X-C motif) ligand 13
chr15_+_97784355 0.158 ENSMUST00000117892.1
 Slc48a1
solute carrier family 48 (heme transporter), member 1
chr6_+_115544664 0.146 ENSMUST00000040234.7
 Tsen2
tRNA splicing endonuclease 2 homolog (S. cerevisiae)
chr15_-_76351008 0.144 ENSMUST00000023211.9
 Sharpin
SHANK-associated RH domain interacting protein
chr14_-_20348040 0.132 ENSMUST00000022344.2
 Ecd
ecdysoneless homolog (Drosophila)
chr17_-_65772686 0.131 ENSMUST00000070673.7
 Rab31
RAB31, member RAS oncogene family
chr3_+_96635840 0.128 ENSMUST00000165842.1
 Pex11b
peroxisomal biogenesis factor 11 beta
chr3_-_33143227 0.120 ENSMUST00000108219.1
 Pex5l
peroxisomal biogenesis factor 5-like
chr15_-_12592556 0.113 ENSMUST00000075317.5
 Pdzd2
PDZ domain containing 2
chr6_-_34878006 0.105 ENSMUST00000115006.1
ENSMUST00000055097.4
ENSMUST00000115007.2
 3110062M04Rik


RIKEN cDNA 3110062M04 gene


chr2_-_130284422 0.100 ENSMUST00000028892.4
 Idh3b
isocitrate dehydrogenase 3 (NAD+) beta
chr11_-_6626030 0.099 ENSMUST00000000394.7
ENSMUST00000136682.1
 Tbrg4

transforming growth factor beta regulated gene 4

chr2_-_170194033 0.086 ENSMUST00000180625.1
 Gm17619
predicted gene, 17619
chr12_-_71136611 0.086 ENSMUST00000021486.8
ENSMUST00000166120.1
 Timm9

translocase of inner mitochondrial membrane 9

chr5_-_130003000 0.070 ENSMUST00000026613.7
 Gusb
glucuronidase, beta
chr9_-_103761820 0.070 ENSMUST00000049452.8
 Tmem108
transmembrane protein 108
chr10_+_94576254 0.068 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr3_+_98280427 0.057 ENSMUST00000090746.2
ENSMUST00000120541.1
 Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr16_-_32165454 0.053 ENSMUST00000115163.3
ENSMUST00000144345.1
ENSMUST00000143682.1
ENSMUST00000115165.3
ENSMUST00000099991.4
ENSMUST00000130410.1
 Nrros





negative regulator of reactive oxygen species





chr4_+_124714776 0.050 ENSMUST00000030734.4
 Sf3a3
splicing factor 3a, subunit 3
chr2_+_181497223 0.046 ENSMUST00000108799.3
 Tpd52l2
tumor protein D52-like 2
chr7_-_105737376 0.028 ENSMUST00000098148.4
 Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr17_-_23684019 0.023 ENSMUST00000085989.5
 Cldn9
claudin 9
chr11_-_116694802 0.022 ENSMUST00000079545.5
 St6galnac2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_+_58963790 0.020 ENSMUST00000075141.6
 Trim17
tripartite motif-containing 17
chr16_+_90386382 0.013 ENSMUST00000065856.6
 Hunk
hormonally upregulated Neu-associated kinase
chrX_+_136666375 0.004 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
 Tceal3


transcription elongation factor A (SII)-like 3


chr15_+_44196135 0.003 ENSMUST00000038856.6
ENSMUST00000110289.3
 Trhr

thyrotropin releasing hormone receptor


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.4 2.8 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 0.7 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.2 1.2 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.2 0.5 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.4 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:2000348 protein linear polyubiquitination(GO:0097039) regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.0 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.7 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)