Motif ID: Zic4

Z-value: 0.899


Transcription factors associated with Zic4:

Gene SymbolEntrez IDGene Name
Zic4 ENSMUSG00000036972.8 Zic4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic4mm10_v2_chr9_+_91378636_91378646-0.104.3e-01Click!


Activity profile for motif Zic4.

activity profile for motif Zic4


Sorted Z-values histogram for motif Zic4

Sorted Z-values for motif Zic4



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_141524379 5.756 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr19_-_57008187 4.810 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr1_+_91179822 4.531 ENSMUST00000097648.4
ENSMUST00000165855.1
Ramp1

receptor (calcitonin) activity modifying protein 1

chr4_-_64046925 4.345 ENSMUST00000107377.3
Tnc
tenascin C
chr11_+_5861886 4.158 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr11_-_102946688 3.748 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr6_-_115251839 3.684 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr19_+_4855129 3.416 ENSMUST00000119694.1
Ctsf
cathepsin F
chr2_+_147187424 3.279 ENSMUST00000144411.1
6430503K07Rik
RIKEN cDNA 6430503K07 gene
chr2_-_152951456 3.265 ENSMUST00000123121.2
Dusp15
dual specificity phosphatase-like 15
chr9_-_29412204 2.834 ENSMUST00000115237.1
Ntm
neurotrimin
chr11_+_121702591 2.757 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr2_+_85136355 2.690 ENSMUST00000057019.7
Aplnr
apelin receptor
chr7_-_16476765 2.690 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr17_-_71310952 2.684 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr2_+_180598219 2.654 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr2_-_152951547 2.653 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr19_+_4099998 2.551 ENSMUST00000049658.7
Pitpnm1
phosphatidylinositol transfer protein, membrane-associated 1
chr14_-_64455903 2.490 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr2_-_152951688 2.414 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chrX_-_49797700 2.380 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr1_-_43163891 2.358 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr17_+_79051906 2.348 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr12_-_56535047 2.238 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr7_+_139834148 2.199 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr5_-_139325616 2.061 ENSMUST00000110865.1
Adap1
ArfGAP with dual PH domains 1
chr2_+_180499893 2.058 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr18_-_80713062 1.981 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr19_+_48206025 1.935 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr4_+_152338887 1.929 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr6_-_35308110 1.925 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr13_-_95223045 1.915 ENSMUST00000162292.1
Pde8b
phosphodiesterase 8B
chr4_+_141368116 1.903 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr7_-_47133395 1.854 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr7_-_47133684 1.849 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr3_-_107986360 1.842 ENSMUST00000066530.6
Gstm2
glutathione S-transferase, mu 2
chr17_-_29237759 1.816 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr3_-_110142996 1.767 ENSMUST00000156177.2
Ntng1
netrin G1
chr3_-_107986408 1.755 ENSMUST00000012348.2
Gstm2
glutathione S-transferase, mu 2
chr4_+_152338619 1.680 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr4_+_130792513 1.608 ENSMUST00000070478.3
Sdc3
syndecan 3
chr3_+_107595031 1.569 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr2_+_32535724 1.538 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr2_+_120977017 1.506 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr2_+_32535315 1.498 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr4_+_117096049 1.463 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr6_+_65671590 1.436 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr17_-_34031644 1.416 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr17_-_34031684 1.398 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr7_+_27591513 1.380 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr14_+_25980039 1.379 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr7_+_27591705 1.275 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr19_-_12501996 1.251 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr14_+_26119811 1.238 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr4_-_57143437 1.230 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr17_-_34031544 1.226 ENSMUST00000025186.8
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr8_-_64693027 1.165 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr16_+_20733104 1.161 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr2_+_164879358 1.159 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr5_-_113310729 1.144 ENSMUST00000112325.1
ENSMUST00000048112.6
Sgsm1

small G protein signaling modulator 1

chr7_+_28766747 1.132 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr2_+_131909928 1.118 ENSMUST00000091288.6
Prnp
prion protein
chr2_+_131909951 1.084 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr17_+_37045963 1.083 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr12_+_24651346 1.071 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr5_-_113310697 1.056 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr19_+_47178820 1.054 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chrX_-_107403295 1.051 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr17_+_46297917 1.028 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr14_-_29721835 1.025 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr17_-_85688252 1.015 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr2_+_91922178 1.001 ENSMUST00000170432.1
Chrm4
cholinergic receptor, muscarinic 4
chr2_+_119325784 0.988 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chr6_-_39118211 0.973 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr9_+_46012810 0.936 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr4_-_11386757 0.935 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr12_-_57546121 0.930 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr11_-_101171302 0.876 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr14_-_54913089 0.863 ENSMUST00000050772.7
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr17_-_26508463 0.852 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr19_-_6235804 0.849 ENSMUST00000025695.9
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr11_-_6475992 0.839 ENSMUST00000179343.1
Purb
purine rich element binding protein B
chr17_+_37045980 0.806 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr14_+_26259109 0.805 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr15_-_33687840 0.790 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr1_+_75546449 0.783 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr2_-_181288016 0.768 ENSMUST00000049032.6
Gmeb2
glucocorticoid modulatory element binding protein 2
chr15_+_74563738 0.765 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr17_-_57059795 0.760 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr9_-_89622986 0.754 ENSMUST00000044491.6
AF529169
cDNA sequence AF529169
chr11_-_69920892 0.743 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chrX_+_73503074 0.741 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr19_-_4477447 0.736 ENSMUST00000059295.3
Syt12
synaptotagmin XII
chr1_-_21961581 0.690 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr7_-_57387172 0.663 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr15_+_7129557 0.659 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr6_-_59426279 0.657 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr12_-_67222549 0.639 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr7_-_70360593 0.635 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr4_-_24851079 0.632 ENSMUST00000084781.5
ENSMUST00000108218.3
Klhl32

kelch-like 32

chr11_+_98741805 0.630 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr9_+_46012822 0.621 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr4_-_156197479 0.620 ENSMUST00000075787.6
ENSMUST00000180572.1
Agrn

agrin

chr13_-_48625571 0.617 ENSMUST00000035824.9
Ptpdc1
protein tyrosine phosphatase domain containing 1
chr4_-_151996113 0.604 ENSMUST00000055688.9
Phf13
PHD finger protein 13
chr7_+_45873127 0.601 ENSMUST00000107718.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr4_+_148130883 0.574 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr7_+_45872772 0.533 ENSMUST00000002855.5
ENSMUST00000107719.1
Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr2_-_130642770 0.518 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr4_-_133602168 0.512 ENSMUST00000057311.3
Sfn
stratifin
chr6_-_83054415 0.506 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr5_+_43233463 0.491 ENSMUST00000169035.1
ENSMUST00000166713.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr11_+_75733037 0.477 ENSMUST00000131398.1
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr4_-_62360436 0.469 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr8_+_72240315 0.467 ENSMUST00000126885.1
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr9_+_108460518 0.451 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr7_-_16286744 0.444 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr17_-_51179249 0.429 ENSMUST00000024717.8
Tbc1d5
TBC1 domain family, member 5
chr2_-_167062607 0.427 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr11_+_57801575 0.426 ENSMUST00000020826.5
Sap30l
SAP30-like
chr11_+_46055973 0.425 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr4_-_62360524 0.425 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr7_-_97579382 0.424 ENSMUST00000151840.1
ENSMUST00000135998.1
ENSMUST00000144858.1
ENSMUST00000146605.1
ENSMUST00000072725.5
ENSMUST00000138060.1
ENSMUST00000154853.1
ENSMUST00000136757.1
ENSMUST00000124552.1
Aamdc








adipogenesis associated Mth938 domain containing








chr8_-_111393810 0.403 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr13_-_37994111 0.397 ENSMUST00000021864.6
Ssr1
signal sequence receptor, alpha
chr11_+_75732869 0.385 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr11_+_61956779 0.361 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_-_71367749 0.353 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr8_+_107031218 0.295 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr3_-_8964037 0.295 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr18_-_24603464 0.295 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr12_+_102128718 0.293 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_+_27653906 0.290 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr10_-_61979073 0.288 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr3_-_95015416 0.284 ENSMUST00000132195.1
Zfp687
zinc finger protein 687
chr8_+_87472838 0.269 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr11_+_97663366 0.264 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr18_-_24603791 0.263 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr5_-_125341043 0.262 ENSMUST00000111390.1
ENSMUST00000086075.6
Scarb1

scavenger receptor class B, member 1

chr7_+_45570342 0.259 ENSMUST00000120864.1
Bcat2
branched chain aminotransferase 2, mitochondrial
chr10_+_45335751 0.259 ENSMUST00000095715.3
Bves
blood vessel epicardial substance
chr4_+_129513581 0.247 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr19_+_5447692 0.242 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr2_-_29253001 0.233 ENSMUST00000071201.4
Ntng2
netrin G2
chr3_+_61002786 0.232 ENSMUST00000029331.1
P2ry1
purinergic receptor P2Y, G-protein coupled 1
chr9_-_63146980 0.229 ENSMUST00000055281.7
ENSMUST00000119146.1
Skor1

SKI family transcriptional corepressor 1

chr11_+_98741871 0.228 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr11_-_85139939 0.220 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr9_+_65346066 0.212 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chr8_+_72240018 0.204 ENSMUST00000003117.8
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr2_+_164960809 0.203 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr17_-_29347902 0.202 ENSMUST00000095427.4
ENSMUST00000118366.1
Mtch1

mitochondrial carrier homolog 1 (C. elegans)

chr2_-_167062981 0.194 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr2_-_167661496 0.187 ENSMUST00000125544.2
ENSMUST00000006587.6
Gm20431
Tmem189
predicted gene 20431
transmembrane protein 189
chr8_-_36613937 0.158 ENSMUST00000033923.7
Dlc1
deleted in liver cancer 1
chr11_+_93996082 0.151 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr16_+_16213318 0.148 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr11_-_115536181 0.147 ENSMUST00000118155.1
ENSMUST00000153892.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)

chr10_-_117845935 0.135 ENSMUST00000064667.7
Rap1b
RAS related protein 1b
chr7_-_100932140 0.133 ENSMUST00000107032.1
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr8_-_45382198 0.132 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr3_+_97658212 0.129 ENSMUST00000045743.6
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr6_+_47877204 0.106 ENSMUST00000061890.7
Zfp282
zinc finger protein 282
chr11_-_70669283 0.103 ENSMUST00000129434.1
ENSMUST00000018431.6
Spag7

sperm associated antigen 7

chr7_+_98703091 0.095 ENSMUST00000033009.9
Prkrir
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr17_-_83631892 0.093 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr11_+_69632927 0.093 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr3_-_95015214 0.092 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
Zfp687


zinc finger protein 687


chr5_-_142509653 0.090 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chr11_-_116335384 0.089 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr2_+_32151074 0.084 ENSMUST00000036691.7
ENSMUST00000069817.8
Prrc2b

proline-rich coiled-coil 2B

chr8_-_64849818 0.079 ENSMUST00000034017.7
Klhl2
kelch-like 2, Mayven
chr4_+_104367549 0.075 ENSMUST00000106830.2
Dab1
disabled 1
chr6_+_99692679 0.074 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr4_+_128883549 0.074 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr16_+_14361552 0.072 ENSMUST00000100167.3
ENSMUST00000154748.1
ENSMUST00000134776.1
Abcc1


ATP-binding cassette, sub-family C (CFTR/MRP), member 1


chr1_+_153665627 0.064 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr7_+_28458658 0.060 ENSMUST00000108288.3
ENSMUST00000055110.9
Lrfn1

leucine rich repeat and fibronectin type III domain containing 1

chr18_+_56707725 0.060 ENSMUST00000025486.8
Lmnb1
lamin B1
chr17_+_83706170 0.051 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr9_-_107710475 0.040 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr11_-_71033462 0.031 ENSMUST00000156068.2
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chrX_+_85574018 0.025 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr17_+_26113286 0.025 ENSMUST00000025010.7
Tmem8
transmembrane protein 8 (five membrane-spanning domains)
chr7_-_34654342 0.024 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr1_+_153665666 0.024 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr8_-_83166170 0.018 ENSMUST00000098605.2
Gm10645
predicted gene 10645
chr5_-_24527276 0.018 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr9_-_58555129 0.011 ENSMUST00000165365.1
Cd276
CD276 antigen

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0061743 motor learning(GO:0061743)
1.1 4.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.0 1.0 GO:0072554 blood vessel lumenization(GO:0072554)
0.9 4.5 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.8 2.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.7 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.7 3.7 GO:2001025 positive regulation of response to drug(GO:2001025)
0.7 3.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.7 3.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.7 2.0 GO:0060854 patterning of lymph vessels(GO:0060854)
0.6 1.9 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.6 1.9 GO:0035106 operant conditioning(GO:0035106)
0.6 5.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 2.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.5 2.1 GO:1903802 positive regulation of arachidonic acid secretion(GO:0090238) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.5 3.6 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.5 2.5 GO:0030091 protein repair(GO:0030091)
0.4 1.2 GO:0030070 insulin processing(GO:0030070)
0.4 1.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4 1.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 0.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.3 0.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.3 1.1 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.3 1.9 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.3 4.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 1.0 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.3 0.8 GO:0097274 urea homeostasis(GO:0097274)
0.2 5.9 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.2 1.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 2.7 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 2.7 GO:0042711 maternal behavior(GO:0042711)
0.2 0.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.2 1.4 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 1.1 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 0.9 GO:1901678 iron coordination entity transport(GO:1901678)
0.2 0.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.6 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.3 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.1 1.9 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.8 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.5 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 1.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.5 GO:0031424 keratinization(GO:0031424) establishment of skin barrier(GO:0061436)
0.1 7.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.7 GO:0032438 melanosome organization(GO:0032438) endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.3 GO:0006549 isoleucine metabolic process(GO:0006549) branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.3 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.9 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.9 GO:0007369 gastrulation(GO:0007369)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 2.9 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.5 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0044301 climbing fiber(GO:0044301)
0.7 2.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.6 3.7 GO:1990635 proximal dendrite(GO:1990635)
0.5 2.1 GO:0032280 symmetric synapse(GO:0032280)
0.4 1.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 4.3 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.1 GO:0033010 paranodal junction(GO:0033010)
0.2 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.9 GO:0005902 microvillus(GO:0005902)
0.1 3.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:0090543 Flemming body(GO:0090543)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.0 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.0 GO:0005581 collagen trimer(GO:0005581)
0.0 2.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 1.1 GO:0097440 apical dendrite(GO:0097440)
0.0 8.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 5.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.1 4.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.9 5.5 GO:0045545 syndecan binding(GO:0045545)
0.5 1.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.4 5.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 4.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 1.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 0.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.3 1.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 3.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.3 2.0 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.3 2.4 GO:0034711 inhibin binding(GO:0034711)
0.2 2.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 2.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 4.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 9.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.6 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 2.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.9 GO:0050815 phosphoserine binding(GO:0050815)
0.1 2.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0043023 GTPase inhibitor activity(GO:0005095) ribosomal large subunit binding(GO:0043023)
0.0 3.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 3.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.9 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 0.7 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 2.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)