Motif ID: Zkscan1

Z-value: 0.691


Transcription factors associated with Zkscan1:

Gene SymbolEntrez IDGene Name
Zkscan1 ENSMUSG00000029729.6 Zkscan1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan1mm10_v2_chr5_+_138085083_138085147-0.247.3e-02Click!


Activity profile for motif Zkscan1.

activity profile for motif Zkscan1


Sorted Z-values histogram for motif Zkscan1

Sorted Z-values for motif Zkscan1



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 114 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_79164477 8.761 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr4_-_42168603 5.194 ENSMUST00000098121.3
 Gm13305
predicted gene 13305
chr8_+_72646679 5.159 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1

chr8_+_72646728 5.003 ENSMUST00000161254.1
 Nwd1
NACHT and WD repeat domain containing 1
chr10_+_86300372 2.913 ENSMUST00000020234.7
 Timp3
tissue inhibitor of metalloproteinase 3
chr4_+_129960760 2.874 ENSMUST00000139884.1
 1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr2_-_27248335 2.817 ENSMUST00000139312.1
 Sardh
sarcosine dehydrogenase
chr5_-_70842617 2.802 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chrX_-_49797700 2.796 ENSMUST00000033442.7
ENSMUST00000114891.1
 Igsf1

immunoglobulin superfamily, member 1

chr3_+_62338344 2.663 ENSMUST00000079300.6
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr13_-_53473074 2.661 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr4_+_138972885 2.565 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
 Tmco4


transmembrane and coiled-coil domains 4


chr14_-_8309770 2.462 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr10_+_90829538 2.007 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_+_24370255 1.995 ENSMUST00000171904.1
 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_-_109722214 1.896 ENSMUST00000020938.7
 Fam20a
family with sequence similarity 20, member A
chrX_+_20870166 1.874 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr19_-_45742873 1.872 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr12_-_72664759 1.833 ENSMUST00000021512.9
 Dhrs7
dehydrogenase/reductase (SDR family) member 7
chr16_+_43762221 1.811 ENSMUST00000023390.4
 Drd3
dopamine receptor D3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.8 GO:0048484 enteric nervous system development(GO:0048484)
0.6 6.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.0 4.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 2.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.9 2.7 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 2.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 2.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.6 1.9 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.4 1.9 GO:0070166 enamel mineralization(GO:0070166)
0.9 1.8 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 1.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 1.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.5 1.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.5 GO:1903975 regulation of glial cell migration(GO:1903975)
0.1 1.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 1.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.3 GO:0046033 AMP metabolic process(GO:0046033)
0.0 1.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 6.3 GO:0005604 basement membrane(GO:0005604)
0.0 4.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 2.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.8 GO:0030139 endocytic vesicle(GO:0030139)
0.1 1.6 GO:0031143 pseudopodium(GO:0031143)
0.2 1.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 1.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.9 GO:0001527 microfibril(GO:0001527)
0.0 0.9 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.1 0.2 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 6.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 4.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.9 2.8 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 2.8 GO:0034711 inhibin binding(GO:0034711)
0.2 2.8 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.5 2.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 1.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.6 1.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.3 1.8 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.6 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 1.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 1.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.4 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)